Klippel-Trenaunay Syndrome (KTS)
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What is Klippel-Trenaunay Syndrome (KTS)?Is there any treatment?What is the prognosis?What research is being done?OrganizationsWhat is Klippel-Trenaunay Syndrome (KTS)?
Klippel-Trenaunay syndrome (KTS) is a congenital circulatory disorder characterized by hemiangiomas (abnormal benign growths
on the skin consisting of masses of blood vessels), arteriovenous abscesses, and varicose veins, usually on the limbs. The
affected limbs may be enlarged and warmer than normal. Fused toes or fingers, or extra toes or fingers, may be present. Bleeding
may occur, often as a result of a rectal or vaginal tumor. The cause of the disorder is unknown. A similar port-wine stain
disorder in which individuals have vascular anomalies and limb enlargement is Sturge-Weber syndrome. These patients may experience
seizures and mental deficiency.
Is there any treatment?
There is no cure for KTS. Treatment is symptomatic. Laser surgery can diminish or erase some skin lesions. Surgery may correct
discrepancies in limb size, but orthopedic devices may be more appropriate.
What is the prognosis?
KTS is a progressive disorder, and complications may be life-threatening.
What research is being done?
The NINDS supports research on congenital disorders such as KTS with the goal of finding new means to treat and prevent them.
Select this link
to view a list of studies currently seeking patients.
Organizations
Prepared by:
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National Institute of Neurological Disorders and Stroke
National Institutes of Health
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Last updated February 13, 2007
