What is MAC?
Many people with HIV get sick with a disease called MAC. This booklet explains what MAC is. It also talks about medicines to help prevent and treat MAC disease -- and how you can help yourself stay healthy.

MAC is short for Mycobacterium avium complex, the germs that cause MAC disease. People get MAC disease when their immune systems are weakened.

MAC germs are all around us -- in the air, water, and soil. People with healthy immune systems don't get sick from MAC germs. People with HIV have weakened immune systems and can become very ill from this infection. Doctors can test for MAC germs in samples of your blood, urine, sputum (spit), or affected body tissues.

Symptoms of MAC
MAC can cause many different problems, but it is most serious when it spreads to organs like the bone marrow, liver, and spleen. These organs keep our blood healthy and in good supply. When MAC spreads through the body, it can cause the symptoms that are listed below:

Symptoms of MAC

  • fever
  • night sweats
  • weight loss
  • tiredness
  • stomach pain
  • diarrhea
Medicines Can Help
Medicines can be used to:
  • Keep your immune system strong. Yo as your doctor prescribes (at the right times and in the right amounts). If you have any questions, ask the clinic staff or your doctor. Write down your doctor's instructions for taking the medicine in the spaces below:

    Name of medicine: ____________________

    Time of day to take: ____________________

    How much to take: ____________________

    How long to keep taking: ____________________

  • Tell you doctor or clinic nurse about any new symptoms or problems. This will help the doctor or nurse decide which tests you need and which medicines are best for you. Most people taking medicine for MAC disease begin to feel better within 4-6 weeks.

    Your medicines may also cause side effects. Your doctor may have to change the amount or type of medicine to reduce your side effects.

    Remember:

    • Take you medicines as your doctor prescribes.
    • Have regular checkups.
    • Report any new symptoms or side effects from your medicines.
Research: Hope for the Future
Many drugs can be used to treat MAC disease, but scientists are still looking for better ways to prevent and treat this disease. Today, many drugs are being tested in research studies. You may be able to help test one of these drugs. If you take part in research, you may help yourself -- and others with HIV.
To Find Out More About MAC
Here are some numbers to call to learn more about MAC disease and how to help yourself.
  • 1-800-342-AIDS
    (1-800-342-2437)

    You can get more information about MAC disease. You can also find out about treatment centers and other help.

  • 1-800-TRIALS-A
    (1-800-874-2572)

    You can find out about testing new drugs. There may be a center near you where you can volunteer for studies that are taking place.

  • 1-800-AIDS-NIH
    (1-800-243-7644)

    Call Monday through Friday from 12:00 p.m. to 3:00 p.m. (Eastern Time) to find out about studies being done at the National Institutes of Health (NIH) Clinical Center.

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