Centers for Disease Control and Prevention

CDC answers your questions about ST. LOUIS ENCEPHALITIS

Q. How do people get St. Louis encephalitis?
A. By the bite of a mosquito (primarily the Culex species) that become infected with St. Louis encephalitis virus (a flavivirus antigenically related to Japanese encephalitis virus).

Q. What is the basic transmission cycle?
A. Mosquitoes become infected by feeding on birds infected with the St. Louis encephalitis virus. Infected mosquitoes then transmit the St. Louis encephalitis virus to humans and animacially in the aged).

Q. How many cases of St. Louis encephalitis occur in the U.S.?
A. Since 1964 there have been 4,478 reported human cases of St. Louis encephalitis, with an average of 128 cases reported annually.

Q. How is St. Louis encephalitis treated?
A. There is no specific therapy. Intensive supportive therapy is indicated.

Q. Is the disease seasonal in its occurrence?
A. In temperate areas of the United States, St. Louis encephalitis cases occur primarily in the late summer or early fall. In the southern United States where the climate is milder St. Louis encephalitis can occur year round.

Q. Who is at risk for getting St. Louis encephalitis?
A. All residents of areas where active cases have been identified are at risk of getting St. Louis encephalitis.

Q. Where does St. Louis encephalitis occur?
A. See map:

St. Louis encephalitis outbreaks can occur throughout most of the United States. The last major epidemic of St. Louis encephalitis occurred inHuman St. Louis Encephalitis Cases by State, 1964-98 the Midwest from 1974-1977. During that outbreak, over 2,500 cases in 35 states were reported to the CDC. Currently, outbreaks of St. Louis encephalitis have been limited in size (usually <30 cases), although the potential still exists for epidemic St. Louis encephalitis. The most recent outbreak of St. Louis encephalitis occurred in New Orleans, Louisiana in 1999, with 20 reported cases.

Q. Is there a vaccine against St. Louis encephalitis?
A. No.

Q. Where can I get more information on St. Louis encephalitis?
A. Visit the CDC website on St. Louis encephalitis: http://www.cdc.gov/ncidod/dvbid/arbor/arboinfo.htm


Division of Vector-Borne Infectious Diseases
National Center for Infectious Diseases
Centers for Disease Control and Prevention
Revised August 2000

Return to top of page Return to top of page

DVBID Home Page DVBID Home Page