Aldoclor-150

What is chlorothiazide and methyldopa?

• have any type of liver disease;
• have an allergy to sulfa-based drugs such as sulfa antibiotics (you may have an allergic reaction to chlorothiazide); or
• are taking a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate).

• have any type of heart disease,
• have had a heart attack or a stroke,
• have kidney disease,
• have high levels of cholesterol or triglycerides (types of fat) in your blood,
• have diabetes,
• have gout,
• have a collagen vascular disease such as systemic lupus erythematosus, or
• have pancreatitis.

• an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
• a very slow heart rate (less than 60 beats per minute);
• unusually high or low blood pressure (fainting, a severe headache, flushing of your face);
• chest pain;
• uncontrollable movements of your arms, legs, or facial muscles;
• yellowing of your skin or eyes;
• unusual bleeding or bruising; or
• little or no urine.

• fatigue, dizziness, tiredness;
• tingling or numbness in your arms, legs, hands, or feet;
• headache;
• constipation, nausea, vomiting, abdominal pain, or diarrhea;
• insomnia;
• increased hunger or thirst or a dry mouth (sucking on ice chips or sugarless hard candy may relieve this side effect);
• excessive urination;
• muscle weakness or cramps;
• blurred vision;
• impotence; or
• sensitivity to sunlight.

• barbiturates such as phenobarbital (Luminal, Solfoton), amobarbital (Amytal), or secobarbital (Seconal), which may cause extreme sleepiness or dizziness if taken with chlorothiazide and methyldopa;
• narcotic pain relievers such as codeine (Tylenol #3, Tylenol #4, others), propoxyphene (Darvon, Darvocet, Wygesic), oxycodone (Percodan, Percocet, Tylox), meperidine (Demerol), morphine (MS Contin, Duramorph, others), and others also may cause extreme sleepiness or dizziness if taken with chlorothiazide and methyldopa;
• steroid medications such as hydrocortisone (Hydrocortone, Cortef), prednisone (Deltasone, Orasone), prednisolone (Delta Cortef, Prelone), methylprednisolone (Medrol), betamethasone (Celestone), dexamethasone (Decadron, Hexadrol), and others, which may increase the side effects of chlorothiazide;
• prescription and over-the-counter cough, cold, allergy, diet, and sleeping pills, which may affect your condition or your treatment with chlorothiazide and methyldopa;
• the cholesterol-lowering drugs cholestyramine (Questran) and colestipol (Colestid), which may decrease the effects of chlorothiazide;
• nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Motrin, Advil), ketoprofen (Orudis, Orudis KT, Oruvail), and naproxen (Naprosyn, Anaprox, Aleve), which may decrease the effects of chlorothiazide and also may increase the risk of damage to your kidneys;
• other commonly used NSAIDs, including diclofenac (Cataflam, Voltaren), etodolac (Lodine), fenoprofen (Nalfon), flurbiprofen (Ansaid), indomethacin (Indocin), ketorolac (Toradol), mefenamic acid (Ponstel), nabumetone (Relafen), oxaprozin (Daypro), piroxicam (Feldene), sulindac (Clinoril), and tolmetin (Tolectin);
• oral antidiabetic drugs such as glipizide (Glucotrol), glyburide (Micronase, Glynase, Diabeta), chlorpropamide (Diabinese), tolazamide (Tolinase), and tolbutamide (Orinase), which may not lower your blood sugar as well during therapy with chlorothiazide and methyldopa (your diabetes therapy may have to be adjusted);
• lithium (Lithobid, Eskalith, others), which should not be taken with chlorothiazide because serious side effects may result; or
• other drugs that also lower blood pressure, including acebutolol (Sectral), atenolol (Tenormin), bisoprolol (Zebeta), carteolol (Cartrol), labetolol (Trandate, Normodyne), propranolol (Inderal), pindolol (Visken), timolol (Blocadren), benazepril (Lotensin), enalapril (Vasotec), captopril (Capoten), fosinopril (Monopril), lisinopril (Prinivil, Zestril), moexipril (Univasc), quinapril (Accupril), ramipril (Altace), amlodipine (Norvasc), bepridil (Vascor), diltiazem (Cardizem, Dilacor), felodipine (Plendil), isradipine (Dynacirc), nicardipine (Cardene), nifedipine (Adalat, Procardia), nimodipine (Nimotop), and verapamil (Calan, Veralan, Isoptin).