Axert Information - Drugs and Treatments

What is almotriptan?

Almotriptan is a headache medicine. It is believed to work by narrowing the blood vessels around the brain. Almotriptan also reduces substances in the body that can trigger headache pain, nausea, sensitivity to light and sound, and other migraine symptoms.

Almotriptan is used to treat migraine headaches in adults and in adolescents who are at least 12 years old.

Almotriptan

will only treat

a headache that has already begun. It

will not prevent

headaches or reduce the number of attacks.

Almotriptan should not be used to treat common tension headaches or any headache that seems to be different from your ususal migraine headaches. Use this medication only if your condition has been confirmed by a doctor as migraine headaches.

Almotriptan may also be used for purposes other than those listed in this medication guide.

What should I discuss with my healthcare provider before taking almotriptan?

You should not use this medication if you are allergic to almotriptan, or if you have:

a history of heart disease, angina (chest pain), blood circulation problems, heart attack, or stroke, including "mini-stroke";
severe or uncontrolled high blood pressure; or
a headache that is not like other headaches you have had.

If you have any of these other conditions, you may need a dose adjustment or special tests to safely take almotriptan:

liver disease;
kidney disease;
ischemic bowel disease;
heart disease, high blood pressure, a heart rhythm disorder;
coronary artery disease (or risk factors that include diabetes, menopause, smoking, being overweight, having high blood pressure or high cholesterol, having a family history of coronary artery disease, being older than 40 and a man, or being a woman who has had a hysterectomy).

FDA pregnancy category C. It is not known whether this medication is harmful to an unborn baby. Before taking almotriptan, tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether almotriptan passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Do not give this medicine to anyone under 18 years old.

How should I take almotriptan?

Take this medication exactly as it was prescribed for you. Never take the medication in larger amounts, or take it for longer than recommended by your doctor. Overuse of migraine headache medicine can actually make your headaches worse. Follow the instructions on your prescription label.

Take almotriptan as soon as you notice headache symptoms, or after an attack has already begun.

Your doctor may want to give your first dose of this medicine in a hospital or clinic setting to see if you have any serious side effects.

Take one almotriptan tablet whole with a full glass of water.

After taking a tablet:

If your headache does not completely go away, or goes away and comes back, take a second tablet two (2) hours after the first.

Do not take more than two (2) almotriptan tablets in 24 hours.

If your symptoms have not improved, contact your doctor before taking any more tablets.

Contact your doctor if you have more than four headaches in one month (30 days).

If you use almotriptan long-term, your doctor may want to check your heart function periodically using an electrocardiograph or ECG (sometimes called an EKG), a machine that measures electrical activity of the heart. This will help your doctor determine if it is still safe for you to use this medication. Do not miss any scheduled visits to your doctor.

Store almotriptan at room temperature away from moisture, heat, and light.

What happens if I miss a dose of almotriptan?

Since almotriptan is used as needed, it does not have a daily dosing schedule. Call your doctor promptly if your symptoms do not improve after using almotriptan.

After taking a almotriptan tablet, you must wait two (2) hours before taking a second tablet.

Do not take more than two (2) almotriptan tablets in 24 hours.

Where can I get more information about almotriptan?

Your pharmacist has information about almotriptan written for health professionals that you may read.

What should I avoid while taking almotriptan?

Do not take almotriptan within 24 hours before or after using another migraine headache medicine,

including:

eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt, Maxalt-MLT), sumatriptan (Imitrex, Treximet), or zolmitriptan (Zomig); or
ergot medicine such as dihydroergotamine (D.H.E. 45, Migranal), ergotamine (Ergomar, Ergostat, Cafergot, Ercaf, Wigraine), ergonovine (Ergotrate), methylergonovine (Methergine), or methysergide (Sansert).

What other drugs will affect almotriptan?

Before taking almotriptan, tell your doctor if you are using any of the following drugs:

diclofenac (Arthrotec, Cataflam, Voltaren, Flector Patch, Solareze);
isoniazid (for treating tuberculosis);
an antidepressant such as citalopram (Celexa), duloxetine (Cymbalta), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil), sertraline (Zoloft), or venlafaxine (Effexor);
an antibiotic such as clarithromycin (Biaxin), dalfopristin/quinupristin (Synercid), or erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin);
an antifungal medication such as itraconazole (Sporanox), ketoconazole (Nizoral), or voriconazole (Vfend);
heart or blood pressure medication such as diltiazem (Cardizem, Dilacor, Tiazac), nicardipine (Cardene), quinidine (Quinaglute, Quinidex, Quin-Release), or verapamil (Calan, Covera, Isoptin, Verelan); or
HIV/AIDS medicine such as atazanavir (Reyataz), delavirdine (Rescriptor), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), saquinavir (Invirase, Fortovase), or ritonavir (Norvir).

This list is not complete and there may be other drugs that can interact with almotriptan. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

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Information, Symptoms, Treatments and Resources

What is almotriptan?



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