Acetazolamide is a carbonic anhydrase inhibitor. Carbonic anhydrase is a protein in your body.
Acetazolamide reduces the activity of this protein.
Acetazolamide is used to treat glaucoma and to treat and to prevent acute mountain sickness
(altitude sickness). It is also used as a part of some treatment plans for congestive heart failure and
seizure disorders.
Acetazolamide may also be used for purposes other than those listed in this medication guide.
What should I discuss with my healthcare provider before taking acetazolamide?
Tell your doctor if you have ever had an allergic reaction to a sulfa-based drug such as
sulfamethoxazole (e.g., Bactrim, Septra, Gantanol). Acetazolamide is also a sulfa-based drug, and you
may have a similar reaction to it.
Before taking acetazolamide, tell your doctor if you
are on aspirin therapy,
have liver disease,
have kidney disease,
have heart disease,
have lung disease, or
have a hormonal disease.
You may not be able to take acetazolamide, or you may require a lower
dose or special monitoring during treatment if you have any of the conditions listed above.
Acetazolamide is in the FDA pregnancy category C. This means that it is not known
whether acetazolamide will harm an unborn baby. Do not take acetazolamide without first talking to
your doctor if you are pregnant.
Acetazolamide passes into breast milk. It is not known whether acetazolamide will affect a
nursing infant. Do not take acetazolamide without first talking to your doctor if you are breast-feeding a
baby.
How should I take acetazolamide?
Take acetazolamide exactly as directed by your doctor. If you do not understand these
directions, ask your pharmacist, nurse, or doctor to explain them to you.
Take each dose with a full glass of water.
Take acetazolamide with food if it upsets your stomach.
Store acetazolamide at room temperature away from moisture and heat.
What happens if I miss a dose of acetazolamide?
Take the missed dose as soon as you remember. However, if it is almost time for your next
dose, skip the missed dose and take only your next regularly scheduled dose.
Do not
take a double dose of this medication.
Where can I get more information about acetazolamide?
Your pharmacist has information about acetazolamide written for health professionals that you may read.
What are the possible side effects of acetazolamide?
If you experience any of the following serious side effects, stop taking acetazolamide and
seek emergency medical attention:
an allergic reaction (difficulty breathing; closing of your throat;
swelling of your lips, tongue, or face; or hives);
a sore throat or a fever;
unusual bleeding or bruising;
side or groin pain;
tingling or tremors in your hands or feet; or
a rash.
Other, less serious side effects may be more likely to occur. Continue to
take acetazolamide and talk to your doctor if you experience
decreased appetite, nausea, vomiting, constipation, diarrhea, or
changes in taste;
drowsiness, dizziness, fatigue, or weakness;
nervousness or mild tremor;
headache or confusion;
increased sensitivity of the skin to sunlight;
worsening gout;
loss of blood sugar control (if you are diabetic);
ringing in your ears or hearing problems; or
changes in your vision.
This is not a complete list of side effects and others may occur. Call your
doctor for medical advice about side effects. You may report side effects to FDA at
1-800-FDA-1088. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about acetazolamide?
Call your doctor immediately if you experience a sore throat, fever, unusual bleeding or bruising,
tingling or tremors in your hands or feet, pain in your side or groin, or a rash. These symptoms could be
early signs of a serious side effect.
Use caution when driving, operating machinery, or performing other hazardous activities.
Acetazolamide may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid
these activities.
Avoid prolonged exposure to sunlight. Acetazolamide may increase the sensitivity of your
skin to sunlight. Use a sunscreen and wear protective clothing when exposure to the sun is unavoidable.
What should I avoid while taking acetazolamide?
Use caution when driving, operating machinery, or performing other hazardous activities.
Acetazolamide may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid
these activities.
Avoid prolonged exposure to sunlight. Acetazolamide may increase the sensitivity of your
skin to sunlight. Use a sunscreen and wear protective clothing when exposure to the sun is unavoidable.
What other drugs will affect acetazolamide?
Before taking this medication, tell your doctor if you are taking any of the following medicines:
cyclosporine (Sandimmune). Cyclosporine may have more side
effects if it is taken with acetazolamide.
primidone (Mysoline). Primidone may not be as effective if
it is taken with acetazolamide, and seizure control may be reduced.
diflunisal (Dolobid). Diflunisal may increase both the
activity and the side effects of acetazolamide.
aspirin, salsalate (Disalcid, Salflex, Salsitab, others),
choline salicylate (Arthropan), magnesium salicylate (Doan's, Magan, Mobidin), and other
aspirin-like products (salicylates). These medicines may also interact with acetazolamide, and
special monitoring of your therapy may be necessary.
lithium (Lithobid, Eskalith, others). Acetazolamide may
decrease the level of lithium in your blood. Special monitoring or a dosage adjustment may be
necessary.
Drugs other than those listed here may also interact with acetazolamide. Talk
to your doctor and pharmacist before taking any prescription or over-the-counter medicines.
What happens if I have an overdose of acetazolamide?
Remember, keep this and all other medicines out of the reach of children, never share
your medicines with others, and use this medication only for the indication prescribed.
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up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum
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Content provided by Multum - Last Updated 11/10/2009