Diuretic Ap-Es

What is hydralazine/hydrochlorothiazide/reserpine?

• have an allergy to sulfa-based drugs such as sulfa antibiotics;
• have coronary heart disease or mitral valvular rheumatic heart disease;
• have peptic ulcer disease (stomach ulcers);
• have ulcerative colitis;
• are suffering from depression (especially if you have suicidal thoughts);
• are receiving electroconvulsive shock therapy; or
• have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days.

• have gallstones,
• have kidney or liver disease,
• have diabetes,
• have gout,
• have a collagen vascular disease such as systemic lupus erythematosus,
• have pancreatitis,
• have asthma,
• have any type of heart disease,
• have had a stroke or a transient ischemic attack (mini-stroke),
• have high cholesterol or high levels of fat in your blood, or
• have pulmonary hypertension (a type of lung disease).

• an allergic reaction (difficulty breathing, closing of your throat, swelling of your lips, tongue or face, hives);
• irregular or fast heartbeats or a fluttering feeling in your chest;
• new or worsening chest pain;
• heart failure (shortness of breath, swelling of ankles or legs, sudden weight gain of 2 pounds in one day or 5 pounds in one week);
• unusual fatigue or confusion;
• abnormal bleeding or bruising;
• yellow skin or eyes;
• blood in your urine or stools;
• little or no urine;
• numbness, tingling, pain, or weakness of your arms or legs; or
• fainting.

• mild fatigue, drowsiness, or dizziness;
• headache;
• water retention (swelling of the hands, feet, or ankles);
• anxiety, depression, or nightmares;
• diarrhea, nausea, vomiting , abdominal pain;
• stuffy nose or a dry mouth;
• muscle weakness or cramps;
• increased hunger, thirst, or urination;
• a rash;
• sensitivity to sunlight; or
• impotence or difficulty ejaculating.

• digoxin (Lanoxin, Lanoxicaps);
• quinidine (Cardioquin, others);
• lithium (Lithobid, Eskalith, others);
• a tricyclic antidepressant such as amitriptyline (Elavil, Endep), imipramine (Tofranil), nortriptyline (Pamelor), doxepin (Sinequan), and others;
• a nonsteroidal anti-inflammatory drug (NSAID) such as ibuprofen (Motrin, Advil), ketoprofen (Orudis, Orudis KT, Oruvail), naproxen (Naprosyn, Anaprox, Aleve), and others;
• an antidiabetic medicine such as glipizide (Glucotrol), glyburide (Micronase, Glynase, Diabeta), and others; or
• a steroid medicine such as prednisone (Orasone, Deltasone), prednisolone (Delta Cortef, Prelone), methylprednisolone (Medrol), and others.