What should I avoid while taking aspirin and hydrocodone?
This medication can cause side effects that may impair your thinking or reactions. Be
careful if you drive or do anything that requires you to be awake and alert.
Do not use any other over-the-counter medication without first asking your doctor or
pharmacist. Aspirin is contained in many medicines available over the counter. If you take certain
products together you may accidentally take too much aspirin. Read the label of any other medicine
you are using to see if it contains aspirin.
Avoid taking acetaminophen (Tylenol) or an NSAID (non-steroidal anti-inflammatory drug)
while you are taking aspirin and hydrocodone, unless your doctor tells you to. NSAIDs include
diclofenac (Voltaren), etodolac (Lodine), ibuprofen (Advil, Motrin), indomethacin (Indocin), meloxicam
(Mobic), nabumetone (Relafen), naproxen (Aleve, Naprosyn), piroxicam (Feldene), and others.
Avoid drinking alcohol while you are taking this medication. Alcohol may increase your
risk of drowsiness or stomach bleeding while taking aspirin and hydrocodone.
What other drugs will affect aspirin and hydrocodone?
Tell your doctor if you are taking an antidepressant such as citalopram (Celexa), duloxetine
(Cymbalta), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, Symbyax), fluvoxamine (Luvox),
paroxetine (Paxil), sertraline (Zoloft), or venlafaxine (Effexor). Taking any of these drugs with aspirin
may cause you to bruise or bleed easily.
Cold or allergy medicine, sedatives, sleeping pills, muscle relaxers, and medicine for
seizures, depression or anxiety can add to sleepiness caused by aspirin and hydrocodone. Tell your
doctor if you regularly use any of these medicines, or any other narcotic pain medicine.
Tell your doctor about all other medications you use, especially:
-
methotrexate (Rheumatrex, Trexall);
-
naltrexone (Vivitrol);
-
plicamycin (Mithracin);
-
valproic acid (Depakene, Stavzor);
-
vancomycin (Vancocin);
-
zidovudine (Retrovir);
-
a blood thinner such as warfarin (Coumadin); or
-
diabetes medications you take by mouth;
-
gout medications such as probenecid (Benemid) or
sulfinpyrazone (Anturane);
-
aspirin or other salicylates such as Backache Relief Extra
Strength, Novasal, Nuprin Backache Caplet, Doan's Pills Extra Strength, Tricosal, and others;
-
an MAO inhibitor such as isocarboxazid (Marplan),
phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine
(Parnate);
-
medication used to prevent blood clots, such as alteplase
(Activase), anistreplase (Eminase), clopidogrel (Plavix), dipyridamole (Persantine),
streptokinase (Kabikinase, Streptase), ticlopidine (Ticlid), and urokinase (Abbokinase); or
-
medication to decrease the acidity of urine, such as sodium
bicarbonate, potassium citrate (K-Lyte, Urocit-K), sodium citrate and citric acid (Bicitra,
Oracit), or sodium citrate and potassium (Citrolith, Polycitra).
This list is not complete and there may be other drugs that can interact with
aspirin and hydrocodone. Tell your doctor about all the prescription and over-the-counter medications
you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do
not start using a new medication without telling your doctor.