MEGESTROL CONCENTRATED SUSPENSION - ORAL
Common Brand Name(s): Megace ES
Phonetic Pronunciation: (meh-JESS-troll)
Information last revised September 2010
What does MEGESTROL CONC SUSP - ORAL look like?

Megace ES 625 mg/5 mL Oral Susp
Uses:
Megestrol is used to increase your appetite and to prevent or reverse unintended or significant weight loss (e.g., muscle wasting). Improving your appetite and gaining weight may increase your ability to fight disease. It can also increase your sense of well-being and your physical ability. Megestrol is similar to a natural substance made by the body called progesterone.
Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.
How To Use
Take this medication by mouth with or without food, usually once daily or as directed by your doctor. Measure the medication with a dose-measuring spoon or device, not a regular teaspoon, to make sure you have the correct dose. The dosage is based on your medical condition and response to therapy. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. It may take several weeks of continued use to see a benefit. Tell your doctor if your condition does not improve or if it worsens. Shake the bottle well before each dose. Do not switch between different forms of megestrol because they may not have the same amount of medication.
Drug Interactions
Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop or change the dosage of any medicine before checking with them first. This drug should not be used with the following medication because very serious interactions may occur. dofetilide. If you are currently using the medication listed above, tell your doctor or pharmacist before starting megestrol. Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: indinavir, diabetes medicine (e.g., glipizide, glyburide, insulin). This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.
Medical Alert
Your condition can cause complications in a medical emergency. For enrollment information call MedicAlert at 1-800-854-1166 (USA), or 1-800-668-1507 (Canada).
Notes
Do not share this medication with others. It is important to keep all doctor appointments so your progress can be monitored and to check for any side effects including high blood pressure.
Overdose
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.
Precautions
Before taking megestrol, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: adrenal gland problems (e.g., Cushing's syndrome), blood clotting problems, diabetes, heart disease (e.g., high blood pressure, congestive heart failure), kidney disease, stomach or abdominal problems, unusual vaginal bleeding. High blood sugar (hyperglycemia) and worsening of diabetes may occur. Symptoms of high blood sugar include thirst, increased urination, confusion, drowsiness, flushing, rapid breathing or fruity breath odor. If these symptoms occur, tell your doctor immediately. People with diabetes should monitor their blood sugar levels more frequently when they start taking this medication and whenever the dose changes since they may need to change their doses of diabetic medications. This drug may decrease adrenal gland activity. Therefore, tell your doctor or dentist that you are currently using megestrol or the date you stopped using it. After stopping this drug, additional corticosteroids (e.g., hydrocortisone) may be necessary during stress situations such as trauma, major surgery, or serious infection. Consult your doctor or pharmacist for details. Symptoms of adrenal problems include unusual weakness, dizziness, nausea, and weight loss. Kidney function declines as you grow older. This medication is removed by the kidneys. Therefore, elderly people may be more sensitive to this drug and to its side effects. This medication must not be used during pregnancy. Megestrol may cause harm to your baby. If you become pregnant or think you may be pregnant, inform your doctor immediately. Women of childbearing age should use an effective form of birth control while using this medication. Consult your doctor for more details. It is unknown if this medication passes into breast milk. Breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.
Storage
Store at room temperature between 59 and 77 degrees F (15 to 25 degrees C), and keep away from moisture and sunlight. Do not store in the bathroom. Keep out of the reach of children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.
Side Effects
This medication may cause trouble sleeping, fever, gas, decreased sexual ability/desire, or upset stomach. Women may experience changes in their menstrual periods, including unpredictable bleeding. If any of these effects persist or worsen, inform your doctor. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor immediately if any of these unlikely but serious side effects occur: fast/pounding heartbeat, fatigue, headache, swelling of the hands/feet. Seek immediate medical attention if any of these rare but very serious side effects occur: chest pain, confusion, difficulty breathing, mental/mood changes, weakness/numbness on one side of the body, pain/redness/swelling of arms or legs, slurred speech, vision changes. A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.
The information contained in the First DataBank databases is intended to supplement the knowledge of physicians, pharmacists, and other healthcare professionals regarding drug therapy problems and patient counselling information. This information is advisory only and is not intended to replace sound clinical judgment in the delivery of healthcare services. First DataBank disclaims all warranties, whether expressed or implied, including any warranty as to the quality, accuracy, and suitability of this information for any purpose.
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