What is esomeprazole?
Esomeprazole decreases the amount of acid produced in the stomach.
Esomeprazole is used to treat symptoms of gastroesophageal reflux disease (GERD) and other
conditions involving excessive stomach acid such as Zollinger-Ellison syndrome. Esomeprazole is also
used to promote healing of erosive esophagitis (damage to your esophagus caused by stomach acid).
Esomeprazole may also be given to prevent gastric ulcer caused by infection with helicobacter
pylori (H. pylori), or by the use of nonsteroidal anti-inflammatory drugs (NSAIDs).
Esomeprazole may also be used for other purposes not listed in this medication guide.
What should I discuss with my healthcare provider before taking esomeprazole?
Do not use this medication if you are allergic to esomeprazole or to any other benzimidazole
medication such as albendazole (Albenza), or mebendazole (Vermox).
Before taking this medication, tell your doctor if you have ever had liver disease or any type
of heart disease. You may need a dose adjustment or special tests during treatment.
Some conditions are treated with a combination of esomeprazole and antibiotics. To best treat
your condition, use all of your medications as directed by your doctor.
Be sure to read the
medication guide or patient instructions provided with each of your medications.
Do
not change your doses or medication schedule without advice from your doctor.
FDA pregnancy category B. This medication is not expected to be harmful to an unborn
baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
It is not known whether esomeprazole passes into breast milk or if it could harm a nursing
baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
How should I take esomeprazole?
Take this medication exactly as it was prescribed for you. Do not take the medication in larger
amounts, or take it for longer than recommended by your doctor. Follow the directions on your
prescription label.
This medicine is usually given for 4 to 8 weeks only. Your doctor may recommend a second
course of treatment if you need additional healing time.
Take each dose with a full glass (8 ounces) of water.
Esomeprazole should be taken at least one hour before a meal.
Do not crush, break, or open a delayed-release capsule. Swallow the pill whole. It is
specially made to release medicine slowly in the body. Breaking or opening the pill would cause too
much of the drug to be released at one time.
You may open the delayed-release capsule and sprinkle the medicine into a spoonful of pudding
or applesauce to make swallowing easier. Swallow this mixture right away without chewing. Do not
save the mixture for later use. Discard the empty capsule.
Esomeprazole can be given through a nasogastric (NG) feeding tube. Open the capsule and
sprinkle the medicine into a 60-milliliter syringe. Mix in 50 milliliters of water. Place the plunger into
the syringe and shake the mixture well. Make sure there are no medicine granules stuck in the tip of the
syringe. Attach the syringe to the NG tube and push the plunger down to empty the syringe into the
tube. Then flush the tube with more water to wash the contents down.
It is important to use esomeprazole regularly to get the most benefit. Get your prescription
refilled before you run out of medicine completely.
Take this medication for the entire length of time prescribed by your doctor. Your
symptoms may get better before your treatment is completed.
Store esomeprazole at room temperature away from moisture and heat.
What happens if I miss a dose of esomeprazole?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the
missed dose and take the medicine at the next regularly scheduled time.
Do not
take
extra medicine to make up the missed dose.
Where can I get more information about esomeprazole?
Your pharmacist has information about esomeprazole written for health professionals that you may read.
What are the possible side effects of esomeprazole?
Get emergency medical help if you have any of these
signs of an allergic
reaction:
hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Less serious side effects may include:
This is not a complete list of side effects and others may occur. Call your
doctor for medical advice about side effects. You may report side effects to FDA at
1-800-FDA-1088. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about esomeprazole?
Do not use this medication if you are allergic to esomeprazole or to any other benzimidazole
medication such as albendazole (Albenza), or mebendazole (Vermox).
Before taking this medication, tell your doctor if you have ever had liver disease or any type
of heart disease. You may need a dose adjustment or special tests during treatment.
Some conditions are treated with a combination of esomeprazole and antibiotics. To best treat
your condition, use all of your medications as directed by your doctor.
Be sure to read the
medication guide or patient instructions provided with each of your medications.
Do
not change your doses or medication schedule without advice from your doctor.
Take this medication for the entire length of time prescribed by your doctor. Your
symptoms may get better before your treatment is completed.
Do not crush, break, or open a delayed-release capsule. Swallow the pill whole. It is
specially made to release medicine slowly in the body. Breaking or opening the pill would cause too
much of the drug to be released at one time.
What should I avoid while taking esomeprazole?
Follow your doctor's instructions about any restrictions on food, beverages, or activity while
you are using esomeprazole.
What other drugs will affect esomeprazole?
Before taking esomeprazole, tell your doctor if you are using any of the following drugs:
-
clopidogrel (Plavix);
-
digoxin (Lanoxin, Lanoxicaps);
-
diazepam (Valium);
-
ketoconazole (Nizoral);
-
HIV or AIDS medication such as atazanavir (Reyataz),
nelfinavir (Viracept), saquinavir (Invirase), and others;
-
iron (Feosol, Mol-Iron, Fergon, Femiron, others); or
-
a blood thinner such as warfarin (Coumadin).
This list is not complete and there may be other drugs that can interact with
esomeprazole. Tell your doctor about all the prescription and over-the-counter medications you use.
This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start
using a new medication without telling your doctor.
What happens if I have an overdose of esomeprazole?