What is aspirin and oxycodone?
Aspirin is in a group of drugs called salicylates (sa-LIS-il-ates). It works by reducing
substances in the body that cause pain, fever, and inflammation.
Oxycodone is in a group of drugs called narcotic pain relievers.
The combination of aspirin and oxycodone is used to relieve moderate to severe pain.
Aspirin and oxycodone may also be used for other purposes not listed in this medication
guide.
What should I discuss with my healthcare provider before taking aspirin and oxycodone?
Aspirin should not be given to a child or teenager who has a fever, especially if the
child also has flu symptoms or chicken pox.
Aspirin can cause a serious and
sometimes fatal condition called Reye's syndrome in children.
Do not use aspirin and oxycodone if you have a bleeding or blood clotting disorder
such as hemophilia. Do not use this medication if you are allergic to aspirin or oxycodone or to a
non-steroidal anti-inflammatory drug (NSAID) such as Aleve, Advil, Motrin, Orudis, Indocin,
Lodine, Voltaren, Toradol, Mobic, Relafen, Feldene, and others.
Oxycodone may be habit-forming and
should be used only by the person
this medicine was prescribed for
. Never give this medication to another person,
especially someone who has a history of drug abuse or addiction. Keep the medication in a
secure place where others cannot get to it.
Before using aspirin and oxycodone, tell your doctor if you have:
-
asthma or other breathing disorders;
-
liver or kidney disease;
-
a history of head injury or brain tumor;
-
epilepsy or other seizure disorder;
-
stomach or intestinal disorder, history of stomach ulcer or
bleeding;
-
a pancreas disorder;
-
curvature of the spine; or
-
mental illness or a history of drug or alcohol addiction.
If you have any of these conditions, you may need a dose adjustment
or special tests to safely take aspirin and oxycodone.
FDA pregnancy category D. This medication can cause harm to an unborn baby, and
breathing problems or addiction/withdrawal symptoms in a newborn.
Taking aspirin
during late pregnancy may cause bleeding in the mother or the baby during delivery.
Do not take aspirin and oxycodone during pregnancy unless your doctor has told you
to. Use an effective form of birth control, and tell your doctor if you become pregnant during
treatment.
Aspirin and oxycodone can pass into breast milk and may harm a nursing baby. Do
not use this medication without telling your doctor if you are breast-feeding a baby.
Older adults may be more sensitive to the effects of this medicine.
How should I take aspirin and oxycodone?
Take this medication exactly as it was prescribed for you. Do not take it in larger
amounts, or use it for longer than recommended by your doctor. Follow the directions on your
prescription label. Tell your doctor if the medicine seems to stop working as well in relieving
your pain.
Drink 6 to 8 full glasses of water daily to help prevent constipation while you are
taking aspirin and oxycodone. Ask your doctor about ways to increase the fiber in your diet. Do
not use a stool softener (laxative) without first asking your doctor.
You may have withdrawal symptoms when you stop using this medication after using
it over a long period of time. Do not stop using the medication suddenly without first talking to
your doctor. You may need to use less and less before you stop the medication completely.
If you need to have any type of surgery, tell the surgeon ahead of time that you are using
aspirin and oxycodone.
Store aspirin and oxycodone at room temperature away from moisture, heat, and
light.
Keep track of how many tablets have been used from each new bottle of this medicine.
Oxycodone is a drug of abuse and you should be aware if any person in the household is using
this medicine improperly or without a prescription.
What happens if I miss a dose of aspirin and oxycodone?
Since aspirin and oxycodone is taken as needed, you may not be on a dosing schedule. If
you are taking the medication regularly, take the missed dose as soon as you remember. If it is
almost time for the next dose, skip the missed dose and wait until your next regularly scheduled
dose.
Do not
use extra medicine to make up the missed dose.
Where can I get more information about aspirin and oxycodone?
Your pharmacist has information about aspirin and oxycodone written for health professionals that you may read.
What are the possible side effects of aspirin and oxycodone?
Get emergency medical help if you have any of these
signs of an allergic
reaction:
hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:
-
black, bloody, or tarry stools, coughing up blood or vomit that
looks like coffee ground;
-
shallow breathing, slow heartbeat;
-
fast heart rate;
-
feeling light-headed, fainting;
-
confusion, hallucinations;
-
easy bruising or bleeding; or
-
problems with urination.
Less serious side effects may include:
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headache, dizziness, drowsiness;
-
heartburn, nausea, vomiting, upset stomach, bloating, gas,
constipation, diarrhea;
-
feeling dizzy or drowsy;
-
headache;
-
sweating;
-
ringing in your ears; or
-
dry mouth.
This is not a complete list of side effects and others may occur. Tell
your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about aspirin and oxycodone?
Aspirin should not be given to a child or teenager who has a fever, especially if the
child also has flu symptoms or chicken pox.
Aspirin can cause a serious and
sometimes fatal condition called Reye's syndrome in children.
Stop using this medication and call your doctor at once if you have any symptoms of
bleeding in your stomach or intestines. Symptoms include black, bloody, or tarry stools, and
coughing up blood or vomit that looks like coffee grounds.
Oxycodone may be habit-forming and
should be used only by the person
this medicine was prescribed for
. Keep the medication in a secure place where others
cannot get to it.
Avoid drinking alcohol while taking aspirin and oxycodone. Alcohol may increase
your risk of stomach bleeding while taking aspirin.
Tell your doctor if the medicine seems to stop working as well in relieving your pain.
What should I avoid while taking aspirin and oxycodone?
This medication can cause side effects that may impair your thinking or reactions.
Be careful if you drive or do anything that requires you to be awake and alert.
Do not use any other over-the-counter cold, allergy, or pain medication without first
asking your doctor or pharmacist. Aspirin is contained in many medicines available over the
counter. If you take certain products together you may accidentally take too much aspirin. Read
the label of any other medicine you are using to see if it contains aspirin.
Avoid drinking alcohol while taking aspirin and oxycodone. Alcohol can increase
the risk of stomach bleeding caused by aspirin.
Cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers,
antidepressants, or seizure medication can add to sleepiness caused by oxycodone, or could slow
your breathing. Tell your doctor if you need to use any of these other medicines while you are
taking aspirin and oxycodone.
What other drugs will affect aspirin and oxycodone?
Before taking this medication, tell your doctor if you are using any of the following drugs:
-
acetazolamide (Diamox);
-
a diuretic (water pill);
-
a blood thinner such as warfarin (Coumadin);
-
insulin or diabetes medications that you take by mouth;
-
an NSAID (non-steroidal anti-inflammatory drug) such as
diclofenac (Voltaren), etodolac (Lodine), indomethacin (Indocin), naproxen (Aleve, Naprosyn),
and others;
-
an ACE inhibitor such as benazepril (Lotensin), captopril
(Capoten), fosinopril (Monopril), enalapril (Vasotec), lisinopril (Prinivil, Zestril), quinapril
(Accupril), and others;
-
a beta-blocker such as atenolol (Tenormin), labetalol
(Normodyne, Trandate), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol
(Inderal, InnoPran), sotalol (Betapace), timolol (Blocadren), and others;
-
a bronchodilator (such as Atrovent, Spiriva), diuretics
(water pills), steroid medicines, or blood thinners;
-
methotrexate (Rheumatrex, Trexall);
-
atropine (Donnatal), dimenhydrinate (Dramamine), or
scopolamine (Transderm-Scop); or
-
bowel or bladder medications such as dicyclomine (Bentyl),
hyoscyamine (Anaspaz, Cystospaz, Levsin), tolterodine (Detrol) and others;
This list is not complete and there may be other drugs that can interact
with aspirin and oxycodone. Tell your doctor about all the prescription and over-the-counter
medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by
other doctors. Do not start using a new medication without telling your doctor.
What happens if I have an overdose of aspirin and oxycodone?
