SOMATROPIN - INJECTION
Common Brand Name(s): Genotropin, Humatrope, Norditropin, Nutropin, Serostim, Zorbtive
Phonetic Pronunciation: (so-mah-TROW-pin)
Information last revised November 2010
What does SOMATROPIN-INJ look like?
Humatrope 5 mg (15 unit) Solution for Injection
Genotropin Miniquick 0.4 mg/0.25 mL Sub-Q Syringe
Genotropin 5 mg/mL (15 unit/mL) SubQ Cartridge
Norditropin Nordiflex 10 mg/1.5 mL (6.7 mg/mL) Sub-Q Pen Injector
Saizen 5 mg Sub-Q Soln
Saizen 8.8 mg Sub-Q Soln
Norditropin FlexPro 10 mg/1.5 mL (6.7 mg/mL) Sub-Q Pen Injector
Norditropin Cartridge 5 mg/1.5 mL (3.3 mg/mL) SubQ Cartridge
Genotropin Miniquick 0.6 mg/0.25 mL Sub-Q Syringe
Humatrope 6 mg (18 unit) Injection, Cartridge
Norditropin Nordiflex 15 mg/1.5 mL (10 mg/mL) Sub-Q Pen Injector
Omnitrope 10 mg/1.5 mL SubQ Cartridge
Omnitrope 5.8 mg Sub-Q Soln
Norditropin Cartridge 15 mg/1.5 mL (10 mg/mL) SubQ Cartridge
Genotropin Miniquick 0.8 mg/0.25 mL Sub-Q Syringe
Humatrope 12 mg (36 unit) Injection, Cartridge
Norditropin Nordiflex 5 mg/1.5 mL (3.3 mg/mL) Sub-Q Pen Injector
Omnitrope 5 mg/1.5 mL (3.3 mg/mL) SubQ Cartridge
Norditropin FlexPro 5 mg/1.5 mL (3.3 mg/mL) Sub-Q Pen Injector
Genotropin Miniquick 0.2 mg/0.25 mL Sub-Q Syringe
Genotropin Miniquick 1.2 mg/0.25 mL Sub-Q Syringe
Humatrope 24 mg (72 unit) Injection, Cartridge
Norditropin Nordiflex 30 mg/3 mL (10 mg/mL) Sub-Q Pen Injector
Saizen click.easy 8.8 mg/1.5 mL (Final Conc.) SubQ Cartridge
Norditropin FlexPro 15 mg/1.5 mL (10 mg/mL) Sub-Q Pen Injector
Uses:
Various brands of this medication are used for the treatment of one of the following medical conditions: growth failure, growth hormone deficiency, intestinal disorder (short bowel syndrome) or HIV-related weight loss or wasting. Somatropin is also used to increase height in children with a certain genetic disorder (Noonan syndrome).
Missed Dose
For the best possible benefit, it is important to receive each scheduled dose of this medication as directed. If you miss a dose, contact your doctor or pharmacist immediately to establish a new dosing schedule.
How To Use
Read the Patient Information Leaflet that may come with your brand of this medication provided by your pharmacist before you start using somatropin and each time you get a refill. If you have any questions, consult your doctor or pharmacist. Some brands of this medication are given by injection into a muscle or under the skin. Some brands may only be injected under the skin. The way you inject this medicine will depend on the brand that you are using. Check with your pharmacist to ensure that the way you are injecting your medicine is correct. It is important to change the location of the injection site to avoid problem areas under the skin. For best results, this medication must be used exactly as prescribed by your doctor. It is important to understand your therapy and to follow your doctor's instructions closely. If you are giving this medication to yourself at home, learn all preparation and usage instructions from your health care professional. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Learn how to store and discard medical supplies safely. If this medicine is used for short bowel syndrome, consult your doctor if a special diet (high carbohydrate/lowfat) or the use of nutritional supplements may be helpful. If this medicine is used for weight loss/muscle wasting, it may take up to 2 weeks to notice the effects of the drug. Do not use more of this medication than prescribed or use it more often since the risk of side effects will be increased.
Drug Interactions
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Some products that may interact with this drug include: drugs to treat diabetes (e.g., insulin, sulfonylureas such as glyburide), estrogen hormone replacement, glucocorticoids (e.g., prednisone, hydrocortisone).
Notes
Laboratory and/or medical tests (e.g., eye exams, thyroid function tests, glucose levels, growth hormone antibody levels) will be done routinely to monitor your response to the medication or check for side effects. Keep all medical appointments and laboratory visits so your therapy can be monitored closely. Consult your doctor for more details.
Overdose
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include severe headache, nausea, or vomiting; sudden onset of sweating, fatigue, shakiness, confusion (hypoglycemia); or persistent swelling of hands and feet.
Precautions
Before using somatropin, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients (such as benzyl alcohol found in some brands), which can cause allergic reactions or other problems. Talk to your pharmacist for more details. This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: eye problems (e.g., diabetic retinopathy), major surgery or trauma, severe breathing problems (acute respiratory failure), undergoing therapy for tumors (cancer), Prader-Willi syndrome (see Side Effects section above), normal growth has stopped (closed epiphyses). Before using this medication, tell your doctor or pharmacist your medical history, especially of: adrenal gland problems, diabetes or family history of diabetes, obesity, kidney disease, tumors (cancer), thyroid problems, back problems (scoliosis), a certain genetic condition (Turner syndrome). When this medication is given to newborns, mix with sterile water for injection that does not contain a preservative. A preservative (benzyl alcohol) which may be found in the liquid used to mix this product can infrequently cause serious problems (sometimes death), if given by injection to an infant during the first months of life. The risk is greater with lower birth weight infants and is greater with increased amounts of benzyl alcohol. Symptoms include sudden gasping, low blood pressure, or a very slow heartbeat. Report these symptoms to the doctor immediately should they occur. Caution is advised when using in the elderly because elderly patients may be more sensitive to its effects. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known if this drug passes into breast milk. Consult your doctor before breast-feeding.
Storage
Consult the product instructions and your pharmacist for storage details. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
Side Effects
Headache, nausea, vomiting, fatigue, muscle pain, or weakness may occur. If these symptoms continue or become bothersome, inform your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: development of a limp, persistent fatigue, unusual/unexplained weight gain, persistent cold intolerance, persistent slow heartbeat, fast heartbeat, ear pain/itching, hearing problems, joint/hip/knee pain, numbness/tingling, unusual increase in thirst or urination, swelling hands/ankles/feet, change in the appearance or size of any mole, severe headache, persistent nausea/vomiting, severe stomach/abdominal pain, vision problems or changes, seizure. Rare (possibly fatal) lung/breathing problems may be caused by this medication in children with Prader-Willi syndrome. Those at higher risk include males, severely overweight children, or those with serious lung/breathing problems ( e.g., sleep apnea, lung infections, lung disease). Children should be checked for certain breathing problems (upper airway obstruction) before and during treatment. Heavy snoring or irregular breathing during sleep (sleep apnea) are signs of airway obstruction. Tell the doctor immediately if these signs occur. Also report any signs of lung infection, such as fever, persistent cough, or trouble breathing. A serious allergic reaction to this drug in unlikely, but get medical help right away if it occurs. Symptoms of a serious allergic reaction include: rash, itching/severe swelling (especially of the face/tongue/throat), dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
