What is acetaminophen and phenyltoloxamine?
Acetaminophen is a pain reliever and a fever reducer.
Phenyltoloxamine is an antihistamine that reduces the natural chemical histamine in the body.
Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.
Acetaminophen and phenyltoloxamine is used to treat runny nose, sneezing, and pain or fever
caused by the common cold, flu, or seasonal allergies.
Acetaminophen and phenyltoloxamine may also be used for other purposes not listed in this
medication guide.
What should I discuss with my healthcare provider before taking acetaminophen and phenyltoloxamine?
You should not take this medication if you are allergic to acetaminophen or
phenyltoloxamine.
Do not use acetaminophen and phenyltoloxamine if you have used an MAO inhibitor such
as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or
tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if
you take acetaminophen and phenyltoloxamine before the MAO inhibitor has cleared from your body.
Ask a doctor or pharmacist about taking acetaminophen and phenyltoloxamine if you have:
Tell your doctor if you drink more than three alcoholic beverages per day or
if you have ever had alcoholic liver disease (cirrhosis). You may not be able to take medication that
contains acetaminophen.
It is not known whether acetaminophen and phenyltoloxamine is harmful to an unborn baby.
Do not take this medication without telling your doctor if you are pregnant.
Acetaminophen and phenyltoloxamine can pass into breast milk and may harm a nursing
baby. Do not take this medication without telling your doctor if you are breast-feeding a baby.
How should I take acetaminophen and phenyltoloxamine?
Use this medication exactly as directed on the label, or as prescribed by your doctor. Do not
use it in larger amounts or for longer than recommended.
Do not take more than 1 gram (1000 mg) of acetaminophen per dose or 4 grams (4000
mg) per day. An acetaminophen overdose can damage your liver. Know the amount of
acetaminophen in the product you are taking.
Call your doctor if your symptoms do not improve, or if you have a fever for longer than 3
days.
This medication can cause you to have unusual results with certain medical tests. Tell any
doctor who treats you that you are taking acetaminophen and phenyltoloxamine.
Store this medication at room temperature away from moisture and heat.
What happens if I miss a dose of acetaminophen and phenyltoloxamine?
Take the missed dose as soon as you remember. If it is almost time for your next dose, wait
until then to take the medicine and skip the missed dose.
Do not
take extra medicine
to make up the missed dose.
Where can I get more information about acetaminophen and phenyltoloxamine?
Your pharmacist has information about acetaminophen and phenyltoloxamine written for health professionals that you may read.
What are the possible side effects of acetaminophen and phenyltoloxamine?
Get emergency medical help if you have any of these
signs of an allergic
reaction:
hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using this medication and call your doctor at once if you have a serious side effect
such as:
-
fast, pounding, or uneven heartbeat;
-
nausea, stomach pain, low fever, loss of appetite, dark
urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or
-
easy bruising or bleeding, unusual weakness, fever, chills,
body aches, flu symptoms.
Less serious side effects may include:
-
dry eyes, nose, and mouth;
-
drowsiness or dizziness;
-
blurred vision;
-
urinating less than usual; or
-
feeling restless or excited (especially in children).
This is not a complete list of side effects and others may occur. Call your
doctor for medical advice about side effects. You may report side effects to FDA at
1-800-FDA-1088.
What is the most important information I should know about acetaminophen and phenyltoloxamine?
Do not use acetaminophen and phenyltoloxamine if you have used an MAO inhibitor such
as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or
tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if
you take acetaminophen and phenyltoloxamine before the MAO inhibitor has cleared from your body.
Acetaminophen and phenyltoloxamine can cause side effects that may impair your thinking
or reactions. Be careful if you drive or do anything that requires you to be awake and alert.
Do not take more of this medication than is recommended. An overdose of acetaminophen
can cause damage to your liver. If you drink more than three alcoholic beverages per day, do not take
acetaminophen without your doctor's advice, and never take more than 2 grams (2000 mg) of
acetaminophen per day.
Do not take this medication without your doctor's advice if you have ever had alcoholic
liver disease (cirrhosis). You may not be able to take acetaminophen.
What should I avoid while taking acetaminophen and phenyltoloxamine?
Acetaminophen and phenyltoloxamine can cause side effects that may impair your thinking
or reactions. Be careful if you drive or do anything that requires you to be awake and alert.
Avoid drinking alcohol while you are taking acetaminophen and phenyltoloxamine. It can
increase your risk of liver damage while taking acetaminophen.
Do not use any other cold, allergy, pain, or sleep medication without first asking your
doctor or pharmacist. Acetaminophen (sometimes abbreviated as "APAP") and antihistamines are
contained in many combination medicines. If you take certain products together you may accidentally
take too much of a certain drug. Read the label of any other medicine you are using to see if it contains
acetaminophen, APAP, or an antihistamine.
What other drugs will affect acetaminophen and phenyltoloxamine?
Tell your doctor if you regularly use other medicines that make you sleepy (such as cold or
allergy medicine, other pain medicines, sleeping pills, muscle relaxers, and medicine for seizures,
depression, or anxiety). They can add to sleepiness caused by phenyltoloxamine.
There may be other drugs that can interact with acetaminophen and phenyltoloxamine. Tell
your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal
products, and drugs prescribed by other doctors. Do not start a new medication without telling your
doctor.
What happens if I have an overdose of acetaminophen and phenyltoloxamine?