What is nifedipine?
Nifedipine is in a class of drugs called calcium channel blockers. Nifedipine relaxes (widens)
your blood vessels (veins and arteries), which makes it easier for the heart to pump and reduces its
workload.
Nifedipine is used to lower hypertension (high blood pressure) and to treat angina (chest pain).
Nifedipine may also be used for purposes other than those listed in this medication guide.
What should I discuss with my healthcare provider before taking nifedipine?
Before taking nifedipine, tell your doctor if you have
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kidney disease;
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liver disease;
-
another disease of the heart or blood vessels such as sick
sinus syndrome, aortic stenosis, heart failure, low blood pressure, or coronary artery disease.
You may not be able to take nifedipine, or you may require a dosage
adjustment or special monitoring during treatment if you have any of the conditions listed above.
Nifedipine is in the FDA pregnancy category C. This means that it is not known whether
nifedipine will be harmful to an unborn baby. Do not take nifedipine without first talking to your doctor
if you are pregnant or could become pregnant during treatment.
Nifedipine passes into breast milk. Do not take nifedipine without first talking to your doctor
if you are breast-feeding a baby.
If you are over 65 years of age, you may be more likely to experience side effects from
nifedipine. Your doctor may prescribe a lower dose of this medication.
How should I take nifedipine?
Take nifedipine exactly as directed by your doctor. If you do not understand these directions,
ask your pharmacist, nurse, or doctor to explain them to you.
Take each dose with a full glass of water.
Adalat CC should be taken on an empty stomach.
Do not crush, chew, or break any form of nifedipine. Swallow the pills whole.
Do not consume grapefruit or grapefruit juice during treatment with nifedipine. Nifedipine
can interact with grapefruit and grapefruit juice, and the interaction may have dangerous effects. You
should discuss the use of grapefruit and grapefruit juice with your doctor.
Occasionally, the Procardia XL tablet shell may be seen in the stool. This is not harmful. The
medicine has been absorbed by the body and the tablet shell is designed to be eliminated in the stool.
Do not stop taking nifedipine without first talking to your doctor, even if you begin to feel
better. If you stop taking the medication, your condition could become worse.
Store nifedipine at room temperature away from moisture and heat.
What happens if I miss a dose of nifedipine?
Take the missed dose as soon as you remember. However, if it is almost time for the next dose,
skip the missed dose and take only the next regularly scheduled dose.
Do not
take a
double dose of this medication.
Where can I get more information about nifedipine?
Your pharmacist has information about nifedipine written for health professionals that you may read.
What are the possible side effects of nifedipine?
If you experience any of the following serious side effects, stop taking nifedipine and
contact your doctor immediately or seek emergency medical treatment:
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an allergic reaction (difficulty breathing; closing of the throat;
swelling of the lips, tongue, or face; or hives);
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unusually fast or slow heartbeats;
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severe dizziness or fainting;
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psychosis;
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yellowing of the skin or eyes (jaundice); or
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swelling of the legs or ankles.
Other, less serious side effects may be more likely to occur. Continue to
take nifedipine and talk to your doctor if you experience
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headache, fatigue, or tiredness;
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flushing;
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insomnia;
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vivid or abnormal dreams;
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nausea or constipation; or
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increased urination.
Side effects other than those listed here may also occur. Talk to your doctor
about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about nifedipine?
Do not stop taking nifedipine without first talking to your doctor, even if you begin to feel
better. If you stop taking the medication, your condition could become worse.
Do not crush, chew, or break any form of nifedipine. Swallow the pills whole.
Do not consume grapefruit or grapefruit juice during treatment with nifedipine. Nifedipine
can interact with grapefruit and grapefruit juice, and the interaction may have dangerous effects. You
should discuss the use of grapefruit and grapefruit juice with your doctor.
What should I avoid while taking nifedipine?
Do not consume grapefruit or grapefruit juice during treatment with nifedipine. Nifedipine
can interact with grapefruit and grapefruit juice, and the interaction may have dangerous effects. You
should discuss the use of grapefruit and grapefruit juice with your doctor.
Follow any recommendations your doctor makes about diet or exercise.
Use caution when you stand or sit up from a lying position, especially if you wake up during
the night. You may become dizzy when changing positions.
Use alcohol cautiously. Alcohol may further lower blood pressure and increase drowsiness
or dizziness while taking nifedipine.
What other drugs will affect nifedipine?
Before taking nifedipine, tell your doctor if you are taking any of the following drugs:
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another heart medication to treat the same or another condition;
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cimetidine (Tagamet, Tagamet HB);
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erythromycin (E-Mycin, E.E.S., Eryc, Ery-Tab, others);
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itraconazole (Sporanox) or ketoconazole (Nizoral);
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carbamazepine (Tegretol);
-
phenytoin (Dilantin); or
-
rifampin (Rifadin, Rimactane) or rifabutin (Mycobutin).
You may not be able to take nifedipine, or you may require a dosage
adjustment or special monitoring if you are taking any of the medicines listed above.
Drugs other than those listed here may also interact with nifedipine or affect your condition. Talk
to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including
herbal products.
What happens if I have an overdose of nifedipine?