What is naproxen?
Naproxen is in a group of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs).
Naproxen works by reducing hormones that cause inflammation and pain in the body.
Naproxen is used to treat pain or inflammation caused by conditions such as arthritis,
ankylosing spondylitis, tendinitis, bursitis, gout, or menstrual cramps.
Naproxen may also be used for other purposes not listed in this medication guide.
What should I discuss with my healthcare provider before taking naproxen?
Taking an NSAID can increase your risk of life-threatening heart or circulation problems,
including heart attack or stroke. This risk will increase the longer you use an NSAID. Do not
use this medicine just before or after having heart bypass surgery (also called coronary artery
bypass graft, or CABG).
NSAIDs can also increase your risk of serious effects on the stomach or intestines,
including bleeding or perforation (forming of a hole). These conditions can be fatal and
gastrointestinal effects can occur without warning at any time while you are taking an NSAID.
Older adults may have an even greater risk of these serious gastrointestinal side effects.
Do not use this medication if you are allergic to naproxen, or if you have a history of
allergic reaction to aspirin or other NSAIDs.
Before taking naproxen, tell your doctor if you are allergic to any drugs, or if you have:
-
a history of heart attack, stroke, or blood clot;
-
heart disease, congestive heart failure, high blood
pressure;
-
a history of stomach ulcers or bleeding;
-
liver or kidney disease;
-
asthma;
-
polyps in your nose;
-
a bleeding or blood clotting disorder; or
-
if you smoke.
If you have any of these conditions, you may not be able to use
naproxen, or you may need a dosage adjustment or special tests during treatment.
FDA pregnancy category C. This medication may be harmful to an unborn baby.
Tell your doctor if you are pregnant or plan to become pregnant during treatment.
Taking naproxen during the last 3 months of pregnancy may result in birth defects.
Do not take naproxen during pregnancy unless your doctor has told you to.
Naproxen can pass into breast milk and may harm a nursing baby. Do not use this
medication without telling your doctor if you are breast-feeding a baby.
Do not give this medicine to a child younger than 2 years old without the advice of a
doctor.
How should I take naproxen?
Take this medication exactly as directed on the label, or as it has been prescribed by your
doctor. Do not use the medication in larger amounts, or use it for longer than recommended.
EC-Naprosyn is a slower-acting form of naproxen and this brand should be used only for
treating arthritis or ankylosing spondylitis. Follow your doctor's instructions.
Do not crush, chew, or break an
extended-release
or
enteric-coated
tablet. Swallow the pill whole. The extended-release pill is specially
made to release medicine slowly in the body. Breaking the pill would cause too much of the drug
to be released at one time. The enteric-coated pill has a special coating to protect your stomach.
Breaking the pill could damage this coating.
Shake the oral suspension (liquid) well just before you measure a dose. To be sure
you get the correct dose, measure the liquid with a marked measuring spoon or medicine cup, not
with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for
one.
If you take naproxen for a long period of time, your doctor may want to check you on a
regular basis to make sure this medication is not causing harmful effects. Do not miss any
scheduled visits to your doctor.
Store naproxen at room temperature away from moisture and heat.
What happens if I miss a dose of naproxen?
Since naproxen is sometimes taken as needed, you may not be on a dosing schedule. If
you are taking the medication regularly, take the missed dose as soon as you remember. If it is
almost time for your next dose, skip the missed dose and take the medicine at your next regularly
scheduled time.
Do not
take extra medicine to make up the missed dose.
Where can I get more information about naproxen?
Your pharmacist has information about naproxen written for health professionals that you may read.
What are the possible side effects of naproxen?
Get emergency medical help if you have any of these
signs of an allergic
reaction:
hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop taking naproxen and seek medical attention or call your doctor at once if you
have any of these serious side effects:
-
chest pain, weakness, shortness of breath, slurred speech, problems
with vision or balance;
-
black, bloody, or tarry stools;
-
coughing up blood or vomit that looks like coffee grounds;
-
swelling or rapid weight gain;
-
urinating less than usual or not at all;
-
nausea, stomach pain, low fever, loss of appetite, dark
urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
-
fever, sore throat, and headache with a severe blistering,
peeling, and red skin rash;
-
bruising, severe tingling, numbness, pain, muscle weakness;
or
-
fever, headache, neck stiffness, chills, increased sensitivity
to light, purple spots on the skin, and/or seizure (convulsions).
Less serious side effects may include:
-
upset stomach, mild heartburn or stomach pain, diarrhea,
constipation;
-
bloating, gas;
-
dizziness, headache, nervousness;
-
skin itching or rash;
-
blurred vision; or
-
ringing in your ears.
This is not a complete list of side effects and others may occur. Tell
your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about naproxen?
This medicine can increase your risk of life-threatening heart or circulation problems,
including heart attack or stroke. This risk will increase the longer you use naproxen. Do not use
this medicine just before or after having heart bypass surgery (also called coronary artery bypass
graft, or CABG).
Seek emergency medical help if you have symptoms of heart or circulation problems,
such as chest pain, weakness, shortness of breath, slurred speech, or problems with vision or
balance.
This medicine can also increase your risk of serious effects on the stomach or intestines,
including bleeding or perforation (forming of a hole). These conditions can be fatal and
gastrointestinal effects can occur without warning at any time while you are taking naproxen.
Older adults may have an even greater risk of these serious gastrointestinal side effects.
Call your doctor at once if you have symptoms of bleeding in your stomach or intestines.
This includes black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee
grounds.
Do not use any other over-the-counter cold, allergy, or pain medication without first
asking your doctor or pharmacist. Many medicines available over the counter contain aspirin or
other medicines similar to naproxen (such as ibuprofen or ketoprofen). If you take certain
products together you may accidentally take too much of this type of medication. Read the label
of any other medicine you are using to see if it contains aspirin, ibuprofen, or ketoprofen.
Do not drink alcohol while taking naproxen. Alcohol can increase the risk of stomach
bleeding caused by naproxen.
Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds).
Naproxen can make your skin more sensitive to sunlight and sunburn may result.
What should I avoid while taking naproxen?
Do not use any other over-the-counter cold, allergy, or pain medication without first
asking your doctor or pharmacist. Many medicines available over the counter contain aspirin or
other medicines similar to naproxen (such as ibuprofen or ketoprofen). If you take certain
products together you may accidentally take too much of this type of medication. Read the label
of any other medicine you are using to see if it contains aspirin, ibuprofen, or ketoprofen.
Do not drink alcohol while taking naproxen. Alcohol can increase the risk of stomach
bleeding caused by naproxen.
Avoid prolonged exposure to sunlight. Naproxen may increase the sensitivity of the
skin to sunlight. Use a sunscreen and wear protective clothing when exposure to the sun is
unavoidable.
What other drugs will affect naproxen?
Tell your doctor if you are taking an antidepressant such as citalopram (Celexa),
duloxetine (Cymbalta), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, Symbyax),
fluvoxamine (Luvox), paroxetine (Paxil), sertraline (Zoloft), or venlafaxine (Effexor). Taking
any of these drugs with naproxen may cause you to bruise or bleed easily.
Before taking naproxen, tell your doctor if you are taking any of the following drugs:
-
a blood thinner such as warfarin (Coumadin);
-
lithium (Eskalith, Lithobid);
-
methotrexate (Rheumatrex, Trexall);
-
diuretics (water pills) such as furosemide (Lasix);
-
steroids (prednisone and others);
-
aspirin or other NSAIDs (non-steroidal anti-inflammatory
drugs) such as diclofenac (Cataflam, Voltaren), etodolac (Lodine), flurbiprofen (Ansaid),
indomethacin (Indocin), ketoprofen (Orudis), ketorolac (Toradol), mefenamic acid (Ponstel),
meloxicam (Mobic), nabumetone (Relafen), piroxicam (Feldene), and others; or
-
an ACE inhibitor such as benazepril (Lotensin), captopril
(Capoten), fosinopril (Monopril), enalapril (Vasotec), lisinopril (Prinivil, Zestril), ramipril
(Altace), and others.
If you are using any of these drugs, you may not be able to use
naproxen or you may need dosage adjustments or special tests during treatment.
There may be other drugs not listed that can affect naproxen. Tell your doctor about all
the prescription and over-the-counter medications you use. This includes vitamins, minerals,
herbal products, and drugs prescribed by other doctors. Do not start using a new medication
without telling your doctor.
What happens if I have an overdose of naproxen?
