Bumetanide is a loop diuretic (water pill) that prevents your body from absorbing too
much salt, allowing the salt to instead be passed in your urine.
Bumetanide treats fluid retention (edema) in people with congestive heart failure, liver
disease, or a kidney disorder such as nephrotic syndrome.
Bumetanide may also be used for other purposes not listed in this medication guide.
What should I discuss with my healthcare provider before taking bumetanide?
Do not use this medication if you have:
severe kidney disease or are unable to urinate;
severe liver disease; or
if you are severely dehydrated.
Before using bumetanide, tell your doctor if you have:
kidney disease;
liver disease;
gout;
lupus;
diabetes; or
an allergy to sulfa drugs.
If you have any of these conditions, you may need a dose adjustment
or special tests to safely take bumetanide.
FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell
your doctor if you are pregnant or plan to become pregnant during treatment.
It is not known whether bumetanide passes into breast milk or if it could harm a
nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a
baby.
How should I take bumetanide?
Take this medication exactly as it was prescribed for you. Do not take the medication in
larger amounts, or take it for longer than recommended by your doctor. Follow the directions on
your prescription label.
Your doctor may occasionally change your dose to make sure you get the best results from
this medication.
Bumetanide will make you urinate more often and you may get dehydrated easily. Follow
your doctor's instructions about using potassium supplements or getting enough salt and
potassium in your diet.
To be sure this medication is not causing harmful effects, your blood will need to be
tested on a regular basis. Your kidney or liver function may also need to be tested. Do not miss
any scheduled appointments.
Store this medication at room temperature away from heat, light, and moisture.
What happens if I miss a dose of bumetanide?
Bumetanide is sometimes used only once, so you may not be on a dosing schedule. If you
are using the medication regularly, take the missed dose as soon as you remember. If it is almost
time for the next dose, skip the missed dose and wait until your next regularly scheduled dose.
Do not
take extra medicine to make up the missed dose.
Where can I get more information about bumetanide?
Your pharmacist has information about bumetanide written for health professionals that you may read.
What are the possible side effects of bumetanide?
Get emergency medical help if you have any of these
signs of an allergic
reaction:
hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using bumetanide and call your doctor at once if you have any of these serious
side effects:
dry mouth, thirst, nausea, vomiting;
feeling weak, drowsy, restless, or light-headed;
fast or uneven heartbeat;
muscle pain or weakness;
easy bruising or bleeding, unusual weakness; or
hearing loss.
Less serious side effects may include:
mild nausea or stomach pain;
headache;
dizziness; or
mild itching or skin rash.
This is not a complete list of side effects and others may occur. Tell
your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about bumetanide?
Do not use this medication if you are unable to urinate, if you have severe liver
disease, or if you are severely dehydrated.
Before using this medication, tell your doctor if you have kidney disease, liver disease,
gout, lupus, diabetes, or an allergy to sulfa drugs.
To be sure this medication is not causing harmful effects, your blood will need to be
tested on a regular basis. Your kidney or liver function may also need to be tested. Do not miss
any scheduled appointments.
Bumetanide will make you urinate more often and you may get dehydrated easily. Follow
your doctor's instructions about using potassium supplements or getting enough salt and
potassium in your diet.
Avoid becoming dehydrated. Follow your doctor's instructions about the type and
amount of liquids you should drink while you are taking bumetanide.
There are many other medicines that can interact with bumetanide. Tell your doctor about
all the prescription and over-the-counter medications you use. This includes vitamins, minerals,
herbal products, and drugs prescribed by other doctors. Do not start using a new medication
without telling your doctor. Keep a list with you of all the medicines you use and show this list
to any doctor or other healthcare provider who treats you.
What should I avoid while taking bumetanide?
Avoid becoming dehydrated. Follow your doctor's instructions about the type and
amount of liquids you should drink while you are taking bumetanide.
What other drugs will affect bumetanide?
Before taking this medication, tell your doctor if you are using any of the following drugs:
lithium;
digoxin (Lanoxin);
cyclosporine (Neoral, Sandimmune, Gengraf);
pentamidine (Nebupent, Pentam);
probenecid (Benemid);
tacrolimus (Prograf);
other diuretics;
blood pressure medications;
amphotericin B (Fungizone, AmBisome, Amphotec,
Abelcet);
antibiotics such as capreomycin (Capastat), rifampin
(Rifadin, Rimactane, Rifater), vancomycin (Vancocin, Vancoled);
antiviral medicines such as acyclovir (Zovirax), adefovir
(Hepsera), cidofovir (Vistide), or foscarnet (Foscavir);
indomethacin or other NSAIDs (non-steroidal
anti-inflammatory drugs) such as aspirin, ibuprofen (Motrin, Advil), diclofenac (Voltaren),
naproxen (Aleve, Naprosyn), piroxicam (Feldene), nabumetone (Relafen), etodolac (Lodine), and
others; or
cancer medicine such as aldesleukin (Proleukin),
carmustine (BiCNU, Gliadel), cisplatin (Platinol), ifosfamide (Ifex), oxaliplatin (Eloxatin),
plicamycin (Mithracin), streptozocin (Zanosar), or tretinoin (Vesanoid).
This list is not complete and there may be other drugs that can interact
with bumetanide. Tell your doctor about all the prescription and over-the-counter medications
you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other
doctors. Do not start using a new medication without telling your doctor.
Remember, keep this and all other medicines out of the reach of children, never share
your medicines with others, and use this medication only for the indication prescribed.
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up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum
information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not
warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does
not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist
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a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or
drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any
given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information
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interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse
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Content provided by Multum - Last Updated 11/10/2009