What is ceftriaxone?
Ceftriaxone is in a group of drugs called cephalosporin (SEF a low spor in) antibiotics. It
works by fighting bacteria in your body.
Ceftriaxone injection is used to treat many kinds of bacterial infections, including severe or
life-threatening forms such as meningitis.
Ceftriaxone may also be used for purposes other than those listed in this medication guide.
What should I discuss with my healthcare provider before taking ceftriaxone?
Do not use this medication if you are allergic to ceftriaxone, or to other cephalosporin
antibiotics, such as:
-
cefaclor (Raniclor);
-
cefadroxil (Duricef);
-
cefazolin (Ancef);
-
cefdinir (Omnicef);
-
cefditoren (Spectracef);
-
cefpodoxime (Vantin);
-
cefprozil (Cefzil);
-
ceftibuten (Cedax);
-
cefuroxime (Ceftin);
-
cephalexin (Keflex); or
-
cephradine (Velosef).
If you have certain conditions, you may need a dose adjustment or special
tests to safely use this medication. Before using ceftriaxone, tell your doctor if you are allergic to any
drugs (especially penicillins), or if you have:
FDA pregnancy category B. This medication is not expected to be
harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during
treatment.
Ceftriaxone can pass into breast milk and may harm a nursing baby. Do not use this
medication without telling your doctor if you are breast-feeding a baby.
Do not use ceftriaxone in a child without a doctor's advice, and never give more than the
child's prescribed dose.
How should I take ceftriaxone?
Ceftriaxone is given as an injection into a muscle or a vein. Your doctor, nurse, or other
healthcare provider will give you this injection. You may be given instructions on how to use your
injections at home. Do not use this medicine at home if you do not fully understand how to give the
injection and properly dispose of needles, syringes, and other items used in giving the medicine.
Use the medication exactly as it was prescribed for you. Do not use it in larger amounts or use
it for longer than recommended by your doctor. Follow the instructions on your prescription label.
You will need to mix ceftriaxone with a liquid (diluent) before using it. If you are using the
injections at home, be sure you understand how to properly mix and store the medication. Use only the
diluent your doctor has recommended.
Do not mix ceftriaxone with any diluent that contains calcium, including a TPN (total
parenteral nutrition) solution.
Use this medication for the entire length of time prescribed by your doctor. Your symptoms
may get better before the infection is completely treated. Ceftriaxone is usually continued for at least 2
days after symptoms disappear.
Ceftriaxone will not treat a viral infection such as the common cold or flu.
Store this medicine at room temperature, away from moisture, heat, and light.
If your medicine was provided in a frozen form or was frozen after mixing, thaw it in a
refrigerator or at room temperature. Do not warm in a microwave or boiling water. Use the medicine
as soon as possible after thawing it. Do not refreeze.
What happens if I miss a dose of ceftriaxone?
Use the medication as soon as you remember the missed dose. If it is almost time for your next
dose, skip the missed dose and use the medicine at your next regularly scheduled time.
Do not
use extra medicine to make up the missed dose.
Where can I get more information about ceftriaxone?
Your pharmacist has information about ceftriaxone written for health professionals that you may read.
What are the possible side effects of ceftriaxone?
Get emergency medical help if you have any of these
signs of an allergic
reaction:
hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:
-
diarrhea that is watery or bloody;
-
fever or chills;
-
skin rash, bruising, severe tingling, numbness, pain, muscle
weakness;
-
blistering, peeling, and red skin rash;
-
white patches or sores inside your mouth or on your lips;
-
pale or yellowed skin, dark colored urine, confusion or
weakness;
-
urinating less than usual or not at all;
-
swelling, pain, or irritation where the injection was given;
or
-
chalky-colored stools, stomach pain just after eating a
meal, nausea, heartburn, bloating, and severe upper stomach pain that may spread to your back.
Less serious side effects may include:
-
nausea, vomiting, stomach pain;
-
headache, dizziness;
-
pain or swelling in your tongue;
-
sweating; or
-
vaginal itching or discharge.
This is not a complete list of side effects and others may occur. Call your
doctor for medical advice about side effects. You may report side effects to FDA at
1-800-FDA-1088.
What is the most important information I should know about ceftriaxone?
Do not use this medication if you are allergic to ceftriaxone, or to similar antibiotics, such as
Ceftin, Cefzil, Keflex, Omnicef, and others.
Before using this medication, tell your doctor if you are allergic to any drugs (especially
penicillin). Also tell your doctor if you have liver or kidney disease, gallbladder problems, a stomach or
intestinal disorder, or if you are malnourished.
Use this medication for the entire length of time prescribed by your doctor. Your symptoms
may get better before the infection is completely treated. Ceftriaxone is usually continued for at least 2
days after symptoms disappear.
Ceftriaxone will not treat a viral infection such as the common cold or flu.
Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have
diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the
diarrhea unless your doctor has told you to.
What should I avoid while taking ceftriaxone?
Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have
diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the
diarrhea unless your doctor has told you to.
What other drugs will affect ceftriaxone?
There may be other drugs that can interact with ceftriaxone. Tell your doctor about all the
prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal
products, and drugs prescribed by other doctors. Do not start using a new medication without telling
your doctor.
What happens if I have an overdose of ceftriaxone?