What is choline magnesium trisalicylate?
Choline magnesium trisalicylate is in a class of drugs called salicylates. It works by
reducing substances in the body that cause pain and inflammation.
Choline magnesium trisalicylate is used to reduce pain and inflammation caused by
conditions such as osteoarthritis, rheumatoid arthritis, other arthritic conditions, and acute painful
shoulder.
Choline magnesium trisalicylate may also be used for purposes other than those listed in
this medication guide.
What should I discuss with my healthcare provider before taking choline magnesium trisalicylate?
Before taking this medication, tell your doctor if you
-
have an allergy to aspirin or any other nonsteroidal
anti-inflammatory drugs (NSAIDs) such as ibuprofen (Motrin, Advil, others), naproxen (Aleve,
Naprosyn, Anaprox, others), indomethacin (Indocin), ketoprofen (Orudis KT, Orudis, Oruvail),
nabumetone (Relafen), oxaprozin (Daypro), and others;
-
have an ulcer or bleeding in your stomach;
-
drink more than three alcoholic beverages a day;
-
have liver disease;
-
have kidney disease;
-
have gout;
-
have a coagulation (bleeding) disorder;
-
have congestive heart failure;
-
have fluid retention;
-
have heart disease; or
-
have high blood pressure.
You may not be able to take choline magnesium trisalicylate, or you
may require a dosage adjustment or special monitoring during treatment if you have any of the
conditions listed above.
Choline magnesium trisalicylate is in the FDA pregnancy category C. This means
that it is not known whether choline magnesium trisalicylate will harm an unborn baby.
Do not
take this medication without first talking to your doctor if you are pregnant.
Choline magnesium trisalicylate passes into breast milk and may harm a nursing
infant. Do not take this medication without first talking to your doctor if you are breast-feeding a
baby.
Do not use choline magnesium trisalicylate to treat a child or teenager who has a
fever, flu symptoms, or chicken pox without first talking to a doctor. In children younger than 18
years of age, this medication may increase the risk of Reye's syndrome, a rare but often fatal
condition.
How should I take choline magnesium trisalicylate?
Take choline magnesium trisalicylate exactly as directed by your doctor or follow the
instructions that accompany the package if you are using an over-the-counter medicine. If you do
not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.
Take each dose with a full glass of water.
Take choline magnesium trisalicylate with milk, food, or an antacid to lessen
stomach upset. Enteric-coated choline magnesium trisalicylate is specially formulated to be
gentle on your stomach. Enteric-coated a choline magnesium trisalicylate can be, but does not
have to be, taken with milk or food and should not be taken with an antacid.
Do not break, chew, or crush the enteric-coated tablets. These have a special coating
to protect your stomach. Swallow them whole.
Do not take choline magnesium trisalicylate more often than every 4 hours, and do not
take more than is recommended. If your condition does not improve within 3 to 4 days, seek
medical attention.
Be aware of the salicylate (aspirin) content of other prescription and over-the-counter
medications to avoid taking too much.
Store choline magnesium trisalicylate at room temperature away from moisture and
heat.
What happens if I miss a dose of choline magnesium trisalicylate?
If you are taking choline magnesium trisalicylate regularly--for example, to treat
arthritis--take the missed dose up to 2 hours late. If more than 2 hours have passed since the
missed dose, skip the missed dose and take only your next regularly scheduled dose.
Do
not
take a double dose.
If you are taking choline magnesium trisalicylate on an as-needed basis and you miss a
dose, take it as soon as you remember. Do not take another dose for at least 4 hours.
Where can I get more information about choline magnesium trisalicylate?
Your pharmacist has information about choline magnesium trisalicylate written for health professionals that you may read.
What are the possible side effects of choline magnesium trisalicylate?
Stop taking choline magnesium trisalicylate and seek emergency medical attention or
contact your doctor immediately if you experience any of the following serious side effects:
-
an allergic reaction (difficulty breathing; closing of your throat;
swelling of your lips, tongue, or face; or hives);
-
black, bloody, or tarry stools;
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nausea, vomiting, or abdominal pain;
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uncontrolled fever;
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blood in your urine or vomit;
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decreased hearing or ringing in the ears;
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seizures; or
-
dizziness, confusion, or hallucinations.
If you experience any of the following less serious side effects, notify
your doctor:
-
heartburn or indigestion,
-
faint ringing in the ears,
-
drowsiness, or
-
headache.
Side effects other than those listed here may also occur. Talk to your
doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about choline magnesium trisalicylate?
Take choline magnesium trisalicylate with milk, food, or an antacid to lessen
stomach upset. Enteric-coated choline magnesium trisalicylate is specially formulated to be
gentle on your stomach. Enteric-coated a choline magnesium trisalicylate can be, but does not
have to be, taken with milk or food and should not be taken with an antacid.
Do not break, chew, or crush the enteric-coated tablets. These have a special coating
to protect your stomach. Swallow them whole.
Avoid alcohol or use it in moderation while taking choline magnesium trisalicylate.
If you drink more than three alcoholic beverages a day, the risk of stomach bleeding may
increase.
What should I avoid while taking choline magnesium trisalicylate?
Avoid taking other over-the-counter or prescription medications containing aspirin or
another salicylate and nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen
(Motrin, Advil, Nuprin, others), naproxen (Aleve, Naprosyn, Anaprox, others), indomethacin
(Indocin), ketoprofen (Orudis KT, Orudis, Oruvail), nabumetone (Relafen), oxaprozin (Daypro),
and others during treatment with choline magnesium trisalicylate. Taking too much of these
medicines can be dangerous.
Avoid alcohol or use it in moderation while taking choline magnesium trisalicylate.
If you drink more than three alcoholic beverages a day, the risk of stomach bleeding may
increase.
Tell your doctor and dentist that you are taking choline magnesium trisalicylate,
especially if you need to undergo a surgical procedure. Choline magnesium trisalicylate may
prolong bleeding.
What other drugs will affect choline magnesium trisalicylate?
Do not take choline magnesium trisalicylate without first talking to your doctor if
you are taking any of the following medicines:
-
an anticoagulant such as warfarin (Coumadin), heparin,
enoxaparin (Lovenox), dalteparin (Fragmin), danaparoid (Orgaran), ardeparin (Normiflo), or
tinzaparin (Innohep);
-
a nonsteroidal anti-inflammatory drug (NSAID) such
as ibuprofen (Motrin, Advil, Nuprin, others), ketoprofen (Orudis, Orudis KT, Oruvail), naproxen
(Naprosyn, Anaprox, Aleve), diclofenac (Voltaren, Cataflam), nabumetone (Relafen), oxaprozin
(Daypro), piroxicam (Feldene), etodolac (Lodine), fenoprofen (Nalfon), flurbiprofen (Ansaid),
indomethacin (Indocin), ketorolac (Toradol), sulindac (Clinoril), or tolmetin (Tolectin); or
-
another salicylate such as aspirin (Acuprin, Ecotrin,
Ascriptin, Bayer, others), magnesium salicylate (Magan, Doan's, Bayer Select Backache Pain
Formula, Mobidin, Arthropan), or salsalate (Disalcid).
You may not be able to take choline magnesium trisalicylate, or you
may require a dosage adjustment or special monitoring if you are taking any of the medicines
listed above.
If you have diabetes, moderate to large doses of choline magnesium trisalicylate may
produce false urine glucose test results.
Many drugs, including those not listed here, can interact with choline magnesium
trisalicylate, resulting in side effects and/or decreased effectiveness of the medications. Do not
take any other prescription or over-the-counter medicines or herbal products without first talking
to your doctor during treatment with choline magnesium trisalicylate.
What happens if I have an overdose of choline magnesium trisalicylate?
