What is escitalopram?
Escitalopram is an antidepressant in a group of drugs called selective serotonin reuptake
inhibitors (SSRIs). Escitalopram affects chemicals in the brain that may become unbalanced and cause
depression or anxiety.
Escitalopram is used to treat anxiety in adults and major depressive disorder in adults and
adolescents who are at least 12 years old.
Escitalopram may also be used for other purposes not listed in this medication guide.
What should I discuss with my healthcare provider before taking escitalopram?
It is dangerous to try and purchase escitalopram on the Internet or from vendors outside of the
United States. Medications distributed from Internet sales may contain dangerous ingredients, or may
not be distributed by a licensed pharmacy. Samples of escitalopram purchased on the Internet have
been found to contain haloperidol (Haldol), a potent antipsychotic drug with dangerous side effects. For
more information, contact the U.S. Food and Drug Administration (FDA) or visit
www.fda.gov/buyonlineguide.
Do not use escitalopram if you are using an MAO inhibitor such as isocarboxazid
(Marplan), tranylcypromine (Parnate), phenelzine (Nardil), rasagiline (Azilect), or selegiline (Eldepryl,
Emsam). Serious and sometimes fatal reactions can occur when these medicines are taken with
escitalopram. You must wait at least 14 days after stopping an MAO inhibitor before you can take
escitalopram. After you stop taking escitalopram, you must wait at least 14 days before you start
taking an MAOI.
Before taking escitalopram, tell your doctor if you are allergic to any drugs, or if you have:
If you have any of these conditions, you may need a dose adjustment or
special tests to safely take escitalopram.
You may have thoughts about suicide when you first start taking an antidepressant, especially if
you are younger than 24 years old. Tell your doctor if you have worsening symptoms of depression or
suicidal thoughts during the first several weeks of treatment, or whenever your dose is changed.
Your family or other caregivers should also be alert to changes in your mood or symptoms.
Your doctor will need to check you at regular visits for at least the first 12 weeks of treatment.
FDA pregnancy category C. SSRI antidepressants may cause serious or life-threatening
lung problems in newborn babies whose mothers take the medication during pregnancy. However, you
may have a relapse of depression if you stop taking your antidepressant during pregnancy. If you are
planning a pregnancy, or if you become pregnant while taking escitalopram, do not stop taking the
medication without first talking to your doctor.
Escitalopram can pass into breast milk and may harm a nursing baby. Do not use this
medication without telling your doctor if you are breast-feeding a baby.
Do not give escitalopram to anyone younger than 12 years old without the advice of a
doctor.
How should I take escitalopram?
Take this medication exactly as it was prescribed for you. Do not take the medication in larger
amounts, or take it for longer than recommended by your doctor. Your doctor may occasionally
change your dose to make sure you get the best results from the medication.
Take each dose with a full glass of water.
Try to take the medicine at the same time each day. Follow the directions on your prescription
label.
To be sure you get the correct dose of liquid escitalopram, measure the liquid with a marked
measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring
device, ask your pharmacist for one.
It may take 4 weeks or longer before you start feeling better. Do not stop using
escitalopram without first talking to your doctor. You may have unpleasant side effects if you stop
taking this medication suddenly.
Store escitalopram at room temperature away from moisture and heat.
What happens if I miss a dose of escitalopram?
Take the missed dose as soon as you remember. However, if it is almost time for the next
regularly scheduled dose, skip the missed dose and take the next one as directed.
Do not
take extra medicine to make up the missed dose.
Where can I get more information about escitalopram?
Your pharmacist has information about escitalopram written for health professionals that you may read.
What are the possible side effects of escitalopram?
Get emergency medical help if you have any of these
signs of an allergic
reaction:
skin rash or hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any new or worsening symptoms such as: mood or
behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated,
hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts
about suicide or hurting yourself.
Call your doctor at once if you have any of these serious side effects:
-
very stiff (rigid) muscles, high fever, sweating, fast or uneven
heartbeats, tremors, overactive reflexes;
-
nausea, vomiting, diarrhea, loss of appetite, feeling
unsteady, loss of coordination; or
-
headache, trouble concentrating, memory problems,
weakness, confusion, hallucinations, fainting, seizure, shallow breathing or breathing that stops.
Less serious side effects may include:
-
drowsiness, dizziness;
-
sleep problems (insomnia);
-
mild nausea, gas, heartburn, upset stomach, constipation;
-
weight changes;
-
decreased sex drive, impotence, or difficulty having an
orgasm; or
-
dry mouth, yawning, ringing in your ears.
This is not a complete list of side effects and others may occur. Call your
doctor for medical advice about side effects. You may report side effects to FDA at
1-800-FDA-1088.
What is the most important information I should know about escitalopram?
Do not take escitalopram together with a monoamine oxidase inhibitor (MAOI) such as
isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or
tranylcypromine (Parnate). You must wait at least 14 days after stopping an MAOI before you can
take escitalopram. After you stop taking escitalopram, you must wait at least 14 days before you start
taking an MAOI.
You may have thoughts about suicide when you first start taking an antidepressant, especially if
you are younger than 24 years old. Your doctor will need to check you at regular visits for at least the
first 12 weeks of treatment.
Call your doctor at once if you have any new or worsening symptoms such as: mood or
behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated,
hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts
about suicide or hurting yourself.
SSRI antidepressants may cause serious or life-threatening lung problems in newborn
babies whose mothers take the medication during pregnancy. However, you may have a relapse of
depression if you stop taking your antidepressant during pregnancy. If you are planning a pregnancy, or
if you become pregnant while taking escitalopram, do not stop taking the medication without first talking
to your doctor.
It is dangerous to try and purchase escitalopram on the Internet or from vendors outside of the
United States. Medications distributed from Internet sales may contain dangerous ingredients, or may
not be distributed by a licensed pharmacy. Samples of escitalopram purchased on the Internet have
been found to contain haloperidol (Haldol), a potent antipsychotic drug with dangerous side effects. For
more information, contact the U.S. Food and Drug Administration (FDA) or visit
www.fda.gov/buyonlineguide.
What should I avoid while taking escitalopram?
Talk to your doctor before taking any medicine for pain, arthritis, fever, or swelling. This
includes aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn), diclofenac (Voltaren),
indomethacin, piroxicam (Feldene), nabumetone (Relafen), etodolac (Lodine), and others.
Taking any of these drugs with escitalopram may cause you to bruise or bleed easily.
Avoid drinking alcohol, which can increase some of the side effects of escitalopram.
Escitalopram can cause side effects that may impair your thinking or reactions. Be careful if
you drive or do anything that requires you to be awake and alert.
Tell your doctor if you regularly use other medicines that make you sleepy (such as cold or
allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures or
anxiety). They can add to sleepiness caused by escitalopram.
What other drugs will affect escitalopram?
Talk to your doctor before taking any medicine for pain, arthritis, fever, or swelling. This
includes aspirin and NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen (Advil, Motrin),
naproxen (Aleve, Naprosyn), diclofenac (Voltaren), indomethacin, piroxicam (Feldene), nabumetone
(Relafen), etodolac (Lodine), and others. Taking any of these drugs with escitalopram may cause you
to bruise or bleed easily.
The following drugs can interact with escitalopram. Tell your doctor if you are using any of
these:
-
carbamazepine (Carbatrol, Tegretol);
-
cimetidine (Tagamet);
-
lithium (Lithobid, Eskalith);
-
a blood thinner such as warfarin (Coumadin);
-
any other antidepressants such as amitriptyline (Elavil),
citalopram (Celexa), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), imipramine (Tofranil),
nortriptyline (Pamelor), paroxetine (Paxil), or sertraline (Zoloft); or
-
almotriptan (Axert), frovatriptan (Frova), sumatriptan
(Imitrex), naratriptan (Amerge), rizatriptan (Maxalt), or zolmitriptan (Zomig).
This list is not complete and there may be other drugs that can interact with
escitalopram. Tell your doctor about all the prescription and over-the-counter medications you use.
This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start
using a new medication without telling your doctor.
What happens if I have an overdose of escitalopram?