What is nitazoxanide?
Nitazoxanide is an antiprotozoal agent.
Nitazoxanide is used to treat diarrhea in adults and children caused by the protozoa Giardia
lamblia. Nitazoxanide is also used to treat diarrhea caused by the protozoa Cryptosporidium parvum.
These conditions are also sometimes referred to as travelers' diarrhea.
Nitazoxanide may also be used for purposes other than those listed in this medication guide.
What should I discuss with my healthcare provider before taking nitazoxanide?
Talk to your doctor before taking nitazoxanide if you have
You may not be able to take nitazoxanide, or you may require a dosage
adjustment or special monitoring during treatment if you have any of the conditions listed above.
The nitazoxanide oral suspension contains 1.48 grams of sucrose per 5 mL (teaspoon).
Individuals with diabetes may need to monitor their intake of sucrose.
Nitazoxanide is in the FDA pregnancy category B. This means that it is not expected to be
harmful to an unborn baby. Do not take nitazoxanide without first talking to your doctor if you are
pregnant or could become pregnant during treatment.
It is not known whether nitazoxanide passes into breast milk. Do not take nitazoxanide
without first talking to your doctor if you are breast-feeding a baby.
How should I take nitazoxanide?
Take nitazoxanide exactly as directed by your doctor. If you do not understand these
instructions, ask your pharmacist, nurse, or doctor to explain them to you.
Take nitazoxanide with food.
Shake the suspension well before measuring a dose. To ensure that you get the correct
dose, measure the suspension with a dose-measuring spoon, dropper, or cup, not with a regular table
spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.
Store the suspension at room temperature. The suspension may be stored for 7 days, after
which any unused portion must be discarded.
What happens if I miss a dose of nitazoxanide?
Take the missed dose as soon as you remember. If you do not remember until it is time for the
next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double
dose of the medication.
Where can I get more information about nitazoxanide?
Your pharmacist has information about nitazoxanide written for health professionals that you may read.
What are the possible side effects of nitazoxanide?
Stop taking nitazoxanide and seek emergency medical attention if you experience a rare
allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives).
Other, less serious side effects may be more likely to occur. Continue to take the medication
and talk to your doctor if you experience
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abdominal pain;
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nausea;
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diarrhea;
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vomiting; or
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headache.
Side effects other than those listed here may also occur. Talk to your doctor
about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about nitazoxanide?
Take nitazoxanide with food.
Talk to your doctor before taking other prescription or over-the-counter medications, including
vitamins, minerals, and herbal products during treatment with nitazoxanide.
What should I avoid while taking nitazoxanide?
There are no restrictions on food, beverages, or activity during treatment with nitazoxanide
unless otherwise directed by your doctor.
What other drugs will affect nitazoxanide?
Many drugs may affect the way that nitazoxanide is metabolized ("broken down") in the body,
leading to higher or lower than expected levels of the medication in the blood. Talk to your doctor
before taking any other medicines during treatment with nitazoxanide.
Talk to your doctor before taking other prescription or over-the-counter medications including
vitamins, minerals, and herbal products during treatment with nitazoxanide.
What happens if I have an overdose of nitazoxanide?