Norethindrone is a form of progesterone, a female hormone. Norethindrone prevents
ovulation (the release of an egg from an ovary). This medication also causes changes in your
cervical mucus and uterine lining, making it harder for sperm to reach the uterus and harder for a
fertilized egg to attach to the uterus.
Norethindrone is used for birth control (contraception) to prevent pregnancy.
Norethindrone is also used to treat menstrual disorders, endometriosis, or abnormal vaginal
bleeding caused by a hormone imbalance.
Norethindrone may also be used for other purposes not listed in this medication guide.
What should I discuss with my healthcare provider before taking norethindrone?
This medication can cause birth defects.
Do not use if you are pregnant.
Tell your doctor right away if you become pregnant.
Do not use this medication if you are allergic to norethindrone, or if you have:
a history of a stroke, blood clot, or circulation problems;
breast cancer;
abnormal vaginal bleeding; or
if you have recently had an incomplete miscarriage or
abortion.
Before using norethindrone, tell your doctor if you have any of the
following conditions. You may need a dose adjustment or special tests to safely take
norethindrone.
high blood pressure or a history of heart disease;
migraines;
kidney disease;
liver disease or liver cancer;
a history of depression or mental illness;
high cholesterol or triglycide (fatty acid) levels in your
blood;
asthma; or
seizures or epilepsy.
Norethindrone can pass into breast milk. Make sure your doctor
knows if you are breast-feeding a baby while taking this medication.
Taking hormones can increase your risk of blood clots, stroke, or heart attack,
especially if you smoke and are older than 35.
How should I take norethindrone?
Take this medication exactly as it was prescribed for you. Do not take the medication in
larger amounts, or take it for longer than recommended by your doctor. Follow the directions on
your prescription label.
You may need to use back-up birth control, such as condoms or a spermicide, when you
first start using this medication. Follow your doctor's instructions.
If you need to have any type of medical tests or surgery, or if you will be on bed rest, you
may need to stop using this medication for a short time. Any doctor or surgeon who treats you
should know that you are using norethindrone.
Your doctor will need to see you on a regular basis while you are using this medication.
Do not miss any appointments.
Store this medication at room temperature away from moisture and heat.
What happens if I miss a dose of norethindrone?
Take the missed dose as soon as you remember. If it is almost time for your next dose,
skip the missed dose and take the medicine at the next regularly scheduled time.
Do not
take extra medicine to make up the missed dose.
Missing a pill increases your risk of becoming pregnant. If you are more than 3 hours late
in taking your dose, use back-up birth control such as condoms or a spermicide for at least the
next 48 hours.
If you miss a period for two months in a row, call your doctor because
you might be pregnant.
Where can I get more information about norethindrone?
Your pharmacist has information about norethindrone written for health professionals that you may read.
What are the possible side effects of norethindrone?
Get emergency medical help if you have any of these
signs of an allergic
reaction:
hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using this medication and call your doctor at once if you have any of these
serious side effects:
sudden numbness or weakness, especially on one side of the body;
sudden headache, confusion, pain behind the eyes,
problems with vision, speech, or balance;
pain or swelling in one or both legs;
migraine headache;
swelling in your hands or feet, rapid weight gain;
symptoms of depression (sleep problems, weakness, mood
changes);
severe pelvic pain;
chest pain or heavy feeling, pain spreading to the arm or
shoulder, nausea, sweating, general ill feeling; or
nausea, stomach pain, low fever, loss of appetite, dark
urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Less serious side effects may include:
mild nausea, vomiting, bloating, stomach cramps;
breast pain, swelling, or tenderness;
dizziness;
freckles or darkening of facial skin;
increased acne or hair growth;
changes in weight;
vaginal itching or discharge;
skin itching or rash;
changes in your menstrual periods, decreased sex drive; or
mild headache.
This is not a complete list of side effects and others may occur. Tell
your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about norethindrone?
This medication can cause birth defects in an unborn baby. Do not use
if you are pregnant.
Use an effective form of birth control, and tell your doctor if you
become pregnant during treatment.
Do not use this medication if you have any of the following conditions: a history of
stroke or blood clot, circulation problems, breast cancer, abnormal vaginal bleeding, liver
disease, or if you have recently had an incomplete miscarriage or abortion.
You may need to use back-up birth control, such as condoms or a spermicide, when you
first start using this medication. Follow your doctor's instructions.
Taking hormones can increase your risk of blood clots, stroke, or heart attack,
especially if you smoke and are older than 35.
Norethindrone does not protect you from sexually transmitted diseases--including HIV
and AIDS. Using a condom is the only way to help protect yourself from these diseases.
What should I avoid while taking norethindrone?
Do not smoke while using norethindrone, especially if you are older than 35.
Smoking can increase your risk of blood clots, stroke, or heart attack caused by norethindrone.
Norethindrone
will not
protect you from sexually transmitted
diseases--including HIV and AIDS. Using a condom is the only way to protect yourself from
these diseases.
What other drugs will affect norethindrone?
Some drugs can make norethindrone less effective, which may result in pregnancy. Before
using norethindrone, tell your doctor if you are using any of the following drugs:
griseofulvin (Fulvicin, Grisactin);
rifampin (Rifadin, Rifater, Rifamate, Rimactane);
St. John's wort;
ketoconazole (Nizoral) or itraconazole (Sporanox);
a barbiturate such as amobarbital (Amytal), butabarbital
(Butisol), mephobarbital (Mebaral), secobarbital (Seconal), or phenobarbital (Luminal,
Solfoton); or
HIV medicines such as amprenavir (Agenerase), atazanavir
(Reyataz), tipranavir (Aptivus), indinavir (Crixivan), saquinavir (Invirase), lopinavir/ritonavir
(Kaletra), fosamprenavir (Lexiva), ritonavir (Norvir), or nelfinavir (Viracept).
There may be other drugs that can interact with norethindrone. Tell
your doctor about all the prescription and over-the-counter medications you use. This includes
vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a
new medication without telling your doctor.
What happens if I have an overdose of norethindrone?
Remember, keep this and all other medicines out of the reach of children, never share
your medicines with others, and use this medication only for the indication prescribed.
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up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum
information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not
warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does
not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist
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a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or
drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any
given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information
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interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse
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Content provided by Multum - Last Updated 11/10/2009