PANTOPRAZOLE DELAYED-RELEASE - ORAL PANTOPRAZOLE DELAYED-RELEASE - ORAL
Common Brand Name(s): Protonix Protonix
Phonetic Pronunciation: (pan-TOE-pruh-zole) (pan-TOE-pruh-zole)
Information last revised September 2010 Information last revised September 2010
What does PANTOPRAZOLE DR TAB look like?
Protonix 40 mg Tab
pantoprazole 40 mg Tab, Delayed Release
Protonix 20 mg Tab
pantoprazole 40 mg Tab, Delayed Release
pantoprazole 20 mg Tab, Delayed Release
pantoprazole 20 mg Tab, Delayed Release
pantoprazole 40 mg Tab, Delayed Release
pantoprazole 20 mg Tab, Delayed Release
Uses:
Pantoprazole is used to treat certain stomach and Pantoprazole is used to treat certain stomach and esophagus problems (such as acid reflux). It works by decreasing esophagus problems (such as acid reflux). It works by decreasing the amount of acid your stomach makes. This medication relieves the amount of acid your stomach makes. This medication relieves symptoms such as heartburn, difficulty swallowing, and persistent symptoms such as heartburn, difficulty swallowing, and persistent cough. It helps heal acid damage to the stomach and esophagus, cough. It helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the helps prevent ulcers, and may help prevent cancer of the esophagus. Pantoprazole belongs to a class of drugs known as esophagus. Pantoprazole belongs to a class of drugs known as proton pump inhibitors (PPIs). proton pump inhibitors (PPIs).
Missed Dose
If you miss a dose, take it as soon as you If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double missed dose and resume your usual dosing schedule. Do not double the dose to catch up. the dose to catch up.
How To Use
Read the Patient Information Leaflet if available Read the Patient Information Leaflet if available from your pharmacist before you start taking pantoprazole and from your pharmacist before you start taking pantoprazole and each time you get a refill. If you have any questions, ask your each time you get a refill. If you have any questions, ask your doctor or pharmacist. doctor or pharmacist. Take this medication by mouth as directed by your doctor, Take this medication by mouth as directed by your doctor, usually once daily. Dosage and length of treatment are based on usually once daily. Dosage and length of treatment are based on your medical condition and response to treatment. your medical condition and response to treatment. If you are taking the tablets, you may take them with or If you are taking the tablets, you may take them with or without food. Swallow the tablets whole. Do not split, crush, or without food. Swallow the tablets whole. Do not split, crush, or chew the medication. Doing so may destroy the drug. chew the medication. Doing so may destroy the drug. If you are taking the granules, take your dose 30 minutes If you are taking the granules, take your dose 30 minutes before a meal. To take it by mouth, open the packet and mix the before a meal. To take it by mouth, open the packet and mix the granules in applesauce or apple juice. Do not mix with other granules in applesauce or apple juice. Do not mix with other foods or liquids. Do not crush or chew the granules. Sprinkle the foods or liquids. Do not crush or chew the granules. Sprinkle the granules on 1 teaspoon (5 milliliters) of applesauce and swallow granules on 1 teaspoon (5 milliliters) of applesauce and swallow all of the mixture right away (within 10 minutes). Follow with all of the mixture right away (within 10 minutes). Follow with sips of water. Or you can mix the granules with 1 teaspoon (5 sips of water. Or you can mix the granules with 1 teaspoon (5 milliliters) of apple juice in a small cup, stir for 5 seconds, milliliters) of apple juice in a small cup, stir for 5 seconds, and swallow all of the mixture right away. To make sure you take and swallow all of the mixture right away. To make sure you take the entire dose, rinse the cup once or twice with apple juice to the entire dose, rinse the cup once or twice with apple juice to mix any remaining granules, and swallow the juice. Do not prepare mix any remaining granules, and swallow the juice. Do not prepare the mixture ahead of time for later use. the mixture ahead of time for later use. If you are giving the granules through a tube into the stomach If you are giving the granules through a tube into the stomach (nasogastric or gastric tube), ask your health care professional (nasogastric or gastric tube), ask your health care professional for detailed instructions on how to properly mix and give it. for detailed instructions on how to properly mix and give it. If needed, antacids may be taken along with this medication. If needed, antacids may be taken along with this medication. If you are also taking sucralfate, take pantoprazole at least 30 If you are also taking sucralfate, take pantoprazole at least 30 minutes before sucralfate. minutes before sucralfate. Use this medication regularly to get the most benefit from it. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. Continue To help you remember, take it at the same time each day. Continue to take this medication for the prescribed length of treatment to take this medication for the prescribed length of treatment even if you are feeling better. even if you are feeling better. Tell your doctor if your condition persists or worsens. Tell your doctor if your condition persists or worsens.
Drug Interactions
See also How to Use section. See also How to Use section. Drug interactions may change how your medications work or Drug interactions may change how your medications work or increase your risk for serious side effects. This document does increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval. medicines without your doctor's approval. Some products that may interact with this drug include: Some products that may interact with this drug include: clopidogrel, nelfinavir. clopidogrel, nelfinavir. Some products need stomach acid so that the body can absorb Some products need stomach acid so that the body can absorb them properly. Pantoprazole decreases stomach acid, so it may them properly. Pantoprazole decreases stomach acid, so it may change how well these products work. Some affected products change how well these products work. Some affected products include amphetamines, ampicillin, atazanavir, iron supplements, include amphetamines, ampicillin, atazanavir, iron supplements, azole antifungals such as ketoconazole, among others. azole antifungals such as ketoconazole, among others. This medication may interfere with certain laboratory tests This medication may interfere with certain laboratory tests (including urine test for tetrahydrocannabinol-THC), possibly (including urine test for tetrahydrocannabinol-THC), possibly causing false test results. Make sure laboratory personnel and causing false test results. Make sure laboratory personnel and all your doctors know you use this drug. all your doctors know you use this drug.
Notes
Do not share this medication with others. Do not share this medication with others. Laboratory and/or medical tests may be performed periodically Laboratory and/or medical tests may be performed periodically to monitor your progress or check for side effects. to monitor your progress or check for side effects.
Overdose
If overdose is suspected, contact a poison control If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call the center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canada residents US National Poison Hotline at 1-800-222-1222. Canada residents can call a provincial poison control center. can call a provincial poison control center.
Precautions
Before taking pantoprazole, tell your doctor or Before taking pantoprazole, tell your doctor or pharmacist if you are allergic to it; or to similar drugs (such pharmacist if you are allergic to it; or to similar drugs (such as lansoprazole, omeprazole); or if you have any other allergies. as lansoprazole, omeprazole); or if you have any other allergies. This product may contain inactive ingredients, which can cause This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for allergic reactions or other problems. Talk to your pharmacist for more details. more details. Before using this medication, tell your doctor or pharmacist Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease. your medical history, especially of: liver disease. Some symptoms may actually be signs of a more serious Some symptoms may actually be signs of a more serious condition. Tell your doctor immediately if you have: heartburn condition. Tell your doctor immediately if you have: heartburn with lightheadedness/sweating/dizziness, chest pain or shoulder with lightheadedness/sweating/dizziness, chest pain or shoulder pain (especially with trouble breathing, sweating, pain (especially with trouble breathing, sweating, lightheadedness, pain spreading to arms/jaw/neck/shoulders), lightheadedness, pain spreading to arms/jaw/neck/shoulders), unexplained weight loss. unexplained weight loss. Proton pump inhibitors (such as pantoprazole) may increase Proton pump inhibitors (such as pantoprazole) may increase your risk for bone fractures, especially with longer use, higher your risk for bone fractures, especially with longer use, higher doses, and in older adults. Talk with your doctor or pharmacist doses, and in older adults. Talk with your doctor or pharmacist about ways to prevent bone loss/fracture, such as by taking about ways to prevent bone loss/fracture, such as by taking calcium (such as calcium citrate) and vitamin D supplements. calcium (such as calcium citrate) and vitamin D supplements. Before having surgery, tell your doctor or dentist about all Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, the products you use (including prescription drugs, nonprescription drugs, and herbal products). nonprescription drugs, and herbal products). During pregnancy, this medication should be used only when During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. clearly needed. Discuss the risks and benefits with your doctor. This medication passes into breast milk. Consult your doctor This medication passes into breast milk. Consult your doctor before breast-feeding. before breast-feeding.
Storage
Store at room temperature away from light and moisture. Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from Do not store in the bathroom. Keep all medications away from children and pets. children and pets. Do not flush medications down the toilet or pour them into a Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist when it is expired or no longer needed. Consult your pharmacist or local waste disposal company. or local waste disposal company.
Side Effects
Headache or diarrhea may occur. If any of these Headache or diarrhea may occur. If any of these effects persist or worsen, tell your doctor or pharmacist effects persist or worsen, tell your doctor or pharmacist promptly. promptly. Remember that your doctor has prescribed this medication Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication than the risk of side effects. Many people using this medication do not have serious side effects. do not have serious side effects. A very serious allergic reaction to this drug is rare. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble (especially of the face/tongue/throat), severe dizziness, trouble breathing. breathing. This is not a complete list of possible side effects. If you This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or notice other effects not listed above, contact your doctor or pharmacist. pharmacist. In the US - In the US - Call your doctor for medical advice about side effects. You Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. may report side effects to FDA at 1-800-FDA-1088. In Canada - Call your doctor for medical advice about side In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at effects. You may report side effects to Health Canada at 1-866-234-2345. 1-866-234-2345.
Other Uses
This section contains uses of this drug that are not This section contains uses of this drug that are not listed in the approved US professional labeling for the drug but listed in the approved US professional labeling for the drug but that may be prescribed by your health care professional. Use this that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it drug for a condition that is listed in this section only if it has been so prescribed by your health care professional. has been so prescribed by your health care professional. This medication may also be used to treat and prevent stomach This medication may also be used to treat and prevent stomach and intestinal ulcers. and intestinal ulcers.