TORSEMIDE - INJECTION
Common Brand Name(s): Demadex
Phonetic Pronunciation: (TOR-seh-mide)
Information last revised May 2010
What does TORSEMIDE - INJECTION look like?
torsemide 50 mg/5 mL (10 mg/mL) IV
torsemide 20 mg/2 mL (10 mg/mL) IV
Uses:
This medication is known as a diuretic (the same kind of drug as a "water pill"). It helps your body get rid of extra water by increasing the amount of urine you make. Getting rid of extra water decreases the strain on your heart and blood vessels, thereby lowering high blood pressure and reducing your risk of strokes, heart attacks, and kidney problems. This effect can also improve symptoms such as trouble breathing and swelling (edema). This injectable form of torsemide is used when the drug cannot be taken by mouth or when extra water must be removed quickly, especially in patients with severe medical conditions.
Missed Dose
If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
How To Use
This medication is given by injection into a vein by a health care professional, usually once daily or as directed by your doctor. Torsemide may be slowly injected over 2 minutes or given by continuous infusion (an IV). Follow your doctor's directions carefully. Dosage is based on your medical condition and response to treatment. Before using this product, check it visually for particles or discoloration. If either is present, do not use the liquid. If you take this drug too close to bedtime, you may need to wake up to urinate. Therefore, it is best to take this medication at least 4 hours before your bedtime. Consult your doctor or pharmacist if you have questions about your dosing schedule. Use this medication regularly to get the most benefit from it. Remember to use it at the same time each day as directed. It is important to continue using this medication even if you feel well. Most people with high blood pressure do not feel sick. Do not stop using this medication without consulting your doctor. If you are giving yourself injections at home, learn how to prepare and inject this medication properly. Ask your doctor, pharmacist, or nurse any questions you may have about how to give yourself torsemide. Learn how to store and discard needles, medical supplies, and any unused medication safely. Consult your pharmacist. Never reuse needles or syringes. Tell your doctor if your condition persists or worsens.
Drug Interactions
Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first. This drug should not be used with the following medication because a very serious interaction may occur: cisapride. If you are currently using this medication listed above, tell your doctor or pharmacist before starting torsemide. Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: other drugs that can affect hearing/balance (e.g., ethacrynic acid, aminoglycoside antibiotics such as gentamicin, tobramycin), amphotericin B, cisplatin, corticosteroids (e.g., prednisone), digoxin, ginseng, lithium, nonsteroidal anti-inflammatory drugs (NSAIDs such as ibuprofen, indomethacin), probenecid, large doses of aspirin and aspirin-like drugs (salicylates). Check the labels on all your medicines (e.g., cough-and-cold products, diet aids, NSAIDs for pain/fever reduction) because they may contain ingredients that could increase your blood pressure or cause swelling (edema). Ask your pharmacist about using these products safely. This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.
Medical Alert
Your condition can cause complications in a medical emergency. For information about enrolling in MedicAlert, call 1-800-854-1166 (USA) or 1-800-668-1507 (Canada).
Notes
Do not share this medication with others. Lifestyle changes such as stress reduction programs, exercise, and dietary changes may increase the effectiveness of this medicine. Talk to your doctor or pharmacist about lifestyle changes that might benefit you. Laboratory and/or medical tests (e.g., blood mineral levels such as potassium, kidney and liver function tests, cholesterol level) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details. Have your blood pressure checked regularly while using this medication. Discuss with your doctor how to monitor your own blood pressure.
Overdose
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: dry mouth, dizziness, excessive urination followed by a decrease in amount of urine, muscle cramps, weakness, fast/irregular heartbeat.
Precautions
Before using torsemide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: severe kidney disease (inability to make urine-anuria). Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, untreated mineral imbalance (e.g., sodium, potassium), gout, lupus. If you have diabetes, torsemide may infrequently make it harder to control your blood sugar. Monitor your blood sugar levels regularly and share the results with your doctor. This drug may reduce the potassium levels in your blood. Ask your doctor about adding potassium to your diet. Your doctor may prescribe a potassium supplement. This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective clothing when outdoors. Before having surgery, tell your doctor or dentist that you are using this medication. This drug may make you dizzy or drowsy or cause blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Limit alcoholic beverages. To reduce dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. Caution is advised when using this drug in the elderly because they may be more sensitive to its effects, especially dizziness. During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. It is unknown whether this drug passes into breast milk. Consult your doctor before breast-feeding.
Storage
Store at room temperature between 59-86 degrees F (15-30 degrees C) away from moisture and light. Do not freeze. Do not store in the bathroom. Keep all medicines away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.
Side Effects
This medication is expected to increase urination. Dizziness, lightheadedness, headache, blurred vision, loss of appetite, stomach upset, diarrhea, constipation, or pain/redness at the injection site may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. This medication may lead the loss of too much body water and minerals (including potassium), causing dehydration. Tell your doctor immediately if you have any of these unlikely but serious symptoms of dehydration or mineral loss: muscle cramps/weakness, confusion, severe dizziness, drowsiness, unusual dry mouth/thirst, nausea/vomiting, fast/irregular heartbeat, unusual decrease in the amount of urine, fainting, seizures. Tell your doctor immediately if any of these unlikely but serious side effects occur: numbness/tingling of the arms/legs, ringing in the ears, hearing loss, decreased sexual ability. Tell your doctor immediately if any of these rare but very serious side effects occur: signs of infection (e.g., fever, persistent sore throat), easy bleeding/bruising, stomach/abdominal pain, persistent nausea/vomiting, yellowing eyes/skin. A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.
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