Before using this medication, tell your doctor if you have a history of hernia, gallstones, Crohn’s disease, Hirschsprung’s disease, impacted bowel movement, diverticulitis, polyps, or any other cause for obstruction in your gastrointestinal (digestive) system.
If you have any of these conditions, you may not be able to use lubiprostone or you may need a dosage adjustment or special tests during treatment.
FDA pregnancy category C: This medication may be harmful to an unborn baby. Do not use lubiprostone without telling your doctor if you are pregnant. You may be asked to have a pregnancy test before you start taking lubiprostone. Tell your doctor if you become pregnant during treatment.
It is not known if lubiprostone passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Take lubiprostone exactly as it was prescribed for you. Do not take it in larger doses or for longer than recommended by your doctor.
Take lubiprostone with food.
Do not take lubiprostone if you have severe diarrhea. Call your doctor for instructions.
Store lubiprostone at room temperature away from moisture and heat.
Take the missed dose as soon as you remember. If it is almost time for your next dose,
skip the missed dose and take the medicine at the next regularly scheduled time.
Stop using lubiprostone and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have severe vomiting or diarrhea .
Less serious side effects are more likely to occur. Continue using lubiprostone and talk with your doctor if you have any of these less serious side effects:
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nausea, vomiting, mild diarrhea, stomach pain or bloating;
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runny or stuffy nose, sneezing, cough;
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headache, dizziness;
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swelling in your hands, ankles, or feet;
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back pain; or
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sore throat.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
Use this medication exactly as it was prescribed for you. Do not use it in larger doses or for longer than recommended by your doctor.
Do not take lubiprostone if you have severe diarrhea. Call your doctor for instructions.
If you miss a dose, use the medication as soon as you remember. If it is almost time for
the next dose, skip the missed dose and wait until your next regularly scheduled dose.
There may be other drugs that can affect lubiprostone. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Stop using this medication and get emergency medical help if you think you have used too much medicine, or if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Less serious side effects are more likely, and you may have none at all. Talk to your doctor about any side effect that seems unusual or is especially bothersome.
There are no restrictions on food, beverages, or activity while using lubiprostone unless your doctor tells you otherwise.
There may be other drugs that can affect lubiprostone. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Seek emergency medical attention if you think you have used too much of this medicine.
Symptoms of a lubiprostone overdose may include vomiting, diarrhea, stomach pain, dizziness, hot flashes, trouble breathing, pale skin, or fainting.