Before your treatment, tell your doctor if you are allergic to mice, hamsters, or drug products made with "murine” proteins.
FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
It is not known whether alglucosidase alfa passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Alglucosidase alfa is given as an injection through a needle placed into a vein. You will receive this injection with an infusion pump in a clinic or hospital setting. The medicine must be given slowly through an IV infusion, and can take up to 4 hours to complete.
This medication is usually given every 2 weeks.
Your name may need to be listed on a patient registry for people with Pompe disease when you start using this medication.
Contact your doctor if you miss a dose of this medication.
Some people receiving an injection of alglucosidase alfa have had a reaction to the infusion (when the medicine is injected into the vein). Tell your caregiver right away if you feel dizzy, nauseated, light-headed, sweaty, itchy, or have a fast heartbeat, cold hands, blue lips, tightness in your chest or throat, wheezing, or trouble breathing during the injection.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:
-
fast or uneven heartbeats;
-
chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;
-
ongoing cough with heaviness in your chest;
-
tremors or shaking;
-
feeling light-headed, fainting; or
-
muscle weakness.
Other less serious side effects are more likely to occur, such as:
-
headache;
-
fever;
-
diarrhea, nausea, vomiting, stomach pain;
-
pain or fullness in your ear;
-
runny or stuffy nose, sore throat, cough; or
-
feeling irritable or agitated.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
Before receiving this medication, tell your doctor if you are allergic to mice, hamsters, or drug products made with "murine” proteins.
Alglucosidase alfa is given as an injection through a needle placed into a vein. You will receive this injection with an infusion pump in a clinic or hospital setting. The medicine must be given slowly through an IV infusion, and can take up to 4 hours to complete.
This medication is usually given every 2 weeks.
Some people receiving an injection of alglucosidase alfa have had a reaction to the infusion (when the medicine is injected into the vein). Tell your caregiver right away if you feel dizzy, nauseated, light-headed, sweaty, itchy, or have a fast heartbeat, cold hands, blue lips, tightness in your chest or throat, wheezing, or trouble breathing during the injection.
There are no restrictions on food, beverages, or activity while receiving alglucosidase alfa unless your doctor has told you otherwise.
There may be other drugs that can affect alglucosidase alfa. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Seek emergency medical attention if you think you have received too much of this medicine. An overdose of alglucosidase alfa is not expected to produce life-threatening symptoms.