cefpodoxime

Generic Name: cefpodoxime
Other Brand Names: Vantin

What is cefpodoxime?

Cefpodoxime is an antibiotic in a class of drugs called cephalosporins. Cefpodoxime fights bacteria in the body.

Cefpodoxime is used to treat many different types of bacterial infections such as bronchitis, pneumonia, tonsillitis, ear infections, sinus infections, skin infections, gonorrhea, and urinary tract infections.

Cefpodoxime may also be used for purposes other than those listed in this medication guide.

Uses Side Effects Precautions Interactions Overdose
What should I discuss with my healthcare provider before taking cefpodoxime?

Do not take cefpodoxime if you have ever had an allergic reaction to another cephalosporin or to a penicillin without first talking to your doctor.

Before taking cefpodoxime, tell your doctor if you have

  • kidney disease, or

  • a gastrointestinal (digestive) disease such as colitis.

You may not be able to take cefpodoxime, or you may require a dosage adjustment or special monitoring during treatment if you have either of the conditions listed above.

The Vantin suspension contains sucrose. Individuals with diabetes may need to be aware of the sucrose contained in this suspension.

Cefpodoxime is in the FDA pregnancy category B. This means that it is not expected to be harmful to an unborn baby. Do not, however, take this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment.

Cefpodoxime passes into breast milk and may affect a nursing baby. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.

How should I take cefpodoxime?

Take this medication exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water.

Take the Vantin tablets with food to increase absorption by the body.

The Vantin suspension can be taken with or without food.

Do not take cefpodoxime at the same time as antacids (e.g., Tums, Maalox, Rolaids, others) or other stomach acid reducers (e.g., Tagamet, Axid, Pepcid, Zantac, Prilosec, Prevacid, Aciphex, Nexium, Protonix). This may decrease the absorption of cefpodoxime.

To ensure that you get a correct dose, measure the liquid form of cefpodoxime with a dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one. Shake the suspension well before measuring a dose.

Take cefpodoxime at evenly spaced intervals to keep a constant level of drug in the body. It is important to take cefpodoxime regularly to get the most benefit.

Take all of the cefpodoxime that has been prescribed for you even if you begin to feel better. Your symptoms may start to improve before the infection is completely treated.

Store the tablets at room temperature away from moisture and heat.

Store the suspension in the refrigerator between 36 and 46 degrees Fahrenheit (2 and 8 degrees Celsius). Throw away any unused medication after 14 days.

What happens if I miss a dose of cefpodoxime?

Take the missed dose as soon as you remember, then try to evenly space the rest of the doses for that day until you can return to a normal schedule. Do not take a double dose of this medication unless otherwise directed by your doctor.

Where can I get more information about cefpodoxime?
Your pharmacist has information about cefpodoxime written for health professionals that you may read.
What are the possible side effects of cefpodoxime?

If you experience any of the following serious side effects, stop taking cefpodoxime and seek emergency medical attention or contact your doctor immediately:

  • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, face, or tongue; hives; or a rash);

  • rash, redness, or itching;

  • severe nausea, vomiting, or diarrhea;

  • mucous or blood in the stool; or

  • unusual bleeding or bruising.

Other, less serious side effects may be more likely to occur. Continue to take cefpodoxime and talk to your doctor if you experience

  • mild nausea or diarrhea, or

  • a yeast infection of the mouth or vagina.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What is the most important information I should know about cefpodoxime?

Take all of the cefpodoxime that has been prescribed for you even if you begin to feel better. Your symptoms may start to improve before the infection is completely treated.

Take the Vantin tablets with food to increase absorption by the body.

The Vantin suspension can be taken with or without food.

What should I avoid while taking cefpodoxime?

Do not take cefpodoxime at the same time as antacids (e.g., Tums, Maalox, Rolaids, others) or other stomach acid reducers (e.g., Tagamet, Axid, Pepcid, Zantac, Prilosec, Prevacid, Aciphex, Nexium, Protonix). This may decrease the absorption of cefpodoxime.

What other drugs will affect cefpodoxime?

Do not take cefpodoxime at the same time as antacids (e.g., Tums, Maalox, Rolaids, others) or other stomach acid reducers (e.g., Tagamet, Axid, Pepcid, Zantac, Prilosec, Prevacid, Aciphex, Nexium, Protonix). This may decrease the absorption of cefpodoxime.

Before taking cefpodoxime, tell your doctor if you are taking any of the following medicines

  • probenecid (Benemid);

  • a loop diuretic (water pill) such as furosemide, bumetanide (Bumex), torsemide (Demadex), or ethacrynic acid (Edecrin);

  • warfarin (Coumadin); or

  • another antibiotic.

You may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.

Drugs other than those listed here may also interact with cefpodoxime. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

What happens if I have an overdose of cefpodoxime?

Seek emergency medical attention.

Symptoms of a cefpodoxime overdose include nausea, vomiting, diarrhea, and abdominal cramps.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Content provided by Multum - Last Updated 2/11/2008