cortisone

Generic Name: cortisone
Other Brand Names: Cortone Acetate

What is cortisone?

Cortisone is in a class of drugs called steroids. Cortisone reduces swelling and decreases the body’s immune response.

Cortisone is used to treat many different conditions. It is used to treat endocrine (hormonal) disorders when the body does not produce enough of its own steroids. It is also used to treat many immune and allergic disorders, such as arthritis, lupus, severe psoriasis, severe asthma, ulcerative colitis, and Crohn’s disease.

Cortisone may also be used for purposes other than those listed in this medication guide.

Uses Side Effects Precautions Interactions Overdose
What should I discuss with my healthcare provider before taking cortisone?

Do not take cortisone if you have a serious bacterial, viral, or fungal infection. Cortisone weakens your body’s immune response and thus its ability to fight infection.

Before taking this medication, tell your doctor if you have

  • kidney disease,

  • liver disease,

  • high blood pressure or heart disease,

  • ulcerative colitis, diverticulitis, or stomach ulcers,

  • hypothyroidism,

  • a psychiatric condition,

  • osteoporosis,

  • myasthenia gravis,

  • diabetes mellitus, or

  • any other medical conditions.

You may not be able to take cortisone, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

Cortisone is in the FDA pregnancy category C. This means that it is not known whether cortisone will harm an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant.

Cortisone passes into breast milk. Do not take cortisone without first talking to your doctor if you are breast-feeding a baby.

How should I take cortisone?

Take cortisone exactly as directed by your doctor. Do not take more or less than is prescribed for you. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water.

Take cortisone with food or milk to lessen stomach upset.

If you are taking one dose daily, take that dose before 9 a.m. if possible, to follow your body’s natural cycle. If you take more than one dose daily, space the doses evenly throughout the day as directed by your doctor.

Do not stop taking cortisone suddenly if you have been taking it for a few weeks. You may need a gradual reduction in dosage before you stop taking this medication.

Carry some type of medical identification that will let others know you are taking cortisone in the case of an emergency.

Store cortisone at room temperature away from moisture and heat.

What happens if I miss a dose of cortisone?

If you take one dose daily, take the missed dose as soon as you remember. However, if you don’t remember until the next day, skip the dose you missed and take only the regular daily dose.

If you take more than one dose daily, you can either take the missed dose as soon as you remember, or you can take two doses (the one you missed plus the regularly scheduled dose) when it is time for your next dose.

If you take one dose every other day, take the missed dose as soon as you remember, then go back to your regular every-other-day schedule.

Where can I get more information about cortisone?
Your pharmacist has information about cortisone written for health professionals that you may read.
What are the possible side effects of cortisone?

If you experience any of the following serious side effects, stop taking cortisone and seek emergency medical attention or contact your doctor immediately:

  • an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);

  • increased blood pressure (severe headache or blurred vision); or

  • sudden weight gain (more than 5 pounds in a day or two).

Other, less serious side effects may be more likely to occur. Continue to take cortisone and talk to your doctor if you experience

  • insomnia;

  • nausea, vomiting, or stomach upset;

  • fatigue or dizziness;

  • muscle weakness or joint pain;

  • problems with diabetes control; or

  • increased hunger or thirst.

Other side effects that occur only rarely, usually with high doses of cortisone, include

  • acne,

  • increased hair growth,

  • thinning of the skin,

  • cataracts,

  • glaucoma,

  • osteoporosis,

  • roundness of the face, and

  • changes in behavior.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What is the most important information I should know about cortisone?

Do not stop taking cortisone suddenly if you have been taking it for a few weeks. You may need a gradual reduction in dosage before you stop taking this medication.

Take cortisone with food or milk to lessen stomach upset.

Carry some type of medical identification that will let others know you are taking cortisone in the case of an emergency.

What should I avoid while taking cortisone?

Use alcohol cautiously. Acting together, alcohol and cortisone can be damaging to the stomach.

Avoid sources of infection. Wash your hands frequently and keep them away from the mouth and eyes. Your immune system may be weakened while taking cortisone.

Do not receive any immunizations during treatment with cortisone without first talking to your doctor.

What other drugs will affect cortisone?

Do not take any other over-the-counter or prescription medications, including herbal products, during treatment with cortisone without first talking to your doctor. Many other medicines can interact with cortisone resulting in side effects or altered effectiveness of the medications.

What happens if I have an overdose of cortisone?

Seek emergency medical attention. A single large dose of this medication is unlikely to cause symptoms or death. An overdose is more likely to be caused by a chronic overdose—large doses taken over a period of time.

Symptoms of an overdose include obesity (especially around the stomach); a round face; increased hair growth (especially around the face); acne; bruising; increased blood pressure; swollen hands, feet, or ankles (fluid retention); and sore or weak muscles.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Content provided by Multum - Last Updated 2/11/2008