Colestid

Generic Name: colestipol
Other Brand Names: colestipol, Colestid Flavored

What is colestipol?

Colestipol is a cholesterol (a type of fat) lowering drug.

Colestipol is used to lower high levels of cholesterol in the blood. Colestipol is especially good at lowering low-density lipoprotein (LDL) ("bad” cholesterol). A rise in triglycerides (another type of fat) may occur.

Lowering high cholesterol levels is an important part of preventing heart disease and arteriosclerosis (hardening of the arteries).

Colestipol may also be used for purposes other than those listed in this medication guide.

Uses Side Effects Precautions Interactions Overdose
What should I discuss with my healthcare provider before taking colestipol?

Do not use colestipol if you have a complete blockage of your biliary or gastrointestinal (stomach) tract.

Before taking this medication, tell your doctor if you

  • have an underactive thyroid gland (hypothyroidism),

  • have diabetes,

  • have kidney disease,

  • have liver disease, or

  • suffer from constipation or hemorrhoids.

You may not be able to take colestipol, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

Before taking the Colestid Flavored brand of colestipol granules, tell your doctor if you have phenylketonuria. These granules contain phenylalanine.

It is not known whether colestipol will harm an unborn baby. Do not take colestipol without first talking to your doctor if you are pregnant.

Colestipol decreases the absorption of certain vitamins, which could become a problem during breast-feeding. Do not take colestipol without first talking to your doctor if you are breast-feeding a baby.

How should I take colestipol?

Take colestipol exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass (8 ounces) of water.

Do not crush, chew, or break the tablets. Swallow them whole.

Mix the granules with a beverage, soup, cereal, or a pulpy fruit such as applesauce or crushed pineapple. The granules will not dissolve, so be sure to stir well. Drink (or eat) the mixture immediately, then add an additional small amount of fluid to the glass and drink it to ensure that you have consumed all of the medicine.

Colestipol is usually taken one or two times a day. Follow your doctor’s instructions.

Increase the amount of fluid in your diet to prevent constipation. Drink at least six to eight full glasses (8 ounces) of fluid daily.

Store colestipol at room temperature away from moisture and heat.

What happens if I miss a dose of colestipol?

Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication.

Where can I get more information about colestipol?
Your pharmacist has information about colestipol written for health professionals that you may read.
What are the possible side effects of colestipol?

If you experience any of the following serious side effects, stop taking colestipol and seek emergency medical attention:

  • an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);

  • an increased heart rate or chest pain;

  • black, bloody, or tarry stools; or

  • unusual bleeding or bruising.

Other, less serious side effects may be more likely to occur. Continue to take colestipol and talk to your doctor if you experience

  • constipation;

  • abdominal pain, cramps, bloating, or flatulence;

  • nausea, vomiting, diarrhea, indigestion, heartburn, or decreased appetite;

  • hiccups or a sour taste in your mouth;

  • headache; or

  • dizziness or drowsiness.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What is the most important information I should know about colestipol?

Follow any diet or exercise plan outlined by your doctor. Diet and exercise are very important factors in controlling cholesterol.

Do not crush, chew, or break the tablets. Swallow them whole.

Increase the amount of fluid in your diet to prevent constipation. Drink at least six to eight full glasses (8 ounces) of fluid daily. Talk to your doctor if constipation becomes a problem.

Take all other medications at least 1 hour before or 4 hours after taking a dose of colestipol. Colestipol can decrease the effectiveness of many other drugs.

What should I avoid while taking colestipol?

Follow any diet or exercise plan outlined by your doctor. Diet and exercise are very important factors in controlling cholesterol.

Increase the amount of fluid in your diet to prevent constipation. Drink at least six to eight full glasses (8 ounces) of fluid daily. Talk to your doctor if constipation becomes a problem.

Take other medications at least 1 hour before or 4 hours after taking a dose of colestipol. Colestipol can decrease the effectiveness of many other drugs if they are taken too close to one another.

What other drugs will affect colestipol?

The absorption of many drugs may be decreased when taken with colestipol. Take all other medications at least 1 hour before or 4 hours after taking a dose of colestipol. The following list includes some, but not all, of the drugs that may have decreased effects when taken with colestipol:

  • pain, fever, and inflammation reducers such as aspirin, ibuprofen (Motrin, Advil), indomethacin (Indocin), ketoprofen (Orudis, Orudis KT, Oruvail), naproxen (Aleve, Anaprox, Naprosyn), and others;

  • antibiotics such as penicillins (Amoxil, Augmentin, Pen VK, Veetids, others), tetracyclines (Sumycin, Achromycin, Minocin, Doryx, Doxy, Vibramycin, others), and clindamycin (Cleocin);

  • heart medicines such as digoxin (Lanoxin, Lanoxicaps), propranolol (Inderal), methyldopa (Aldomet), furosemide (Lasix), hydrochlorothiazide (HCTZ, HydroDiuril), chlorothiazide (Diuril), metolazone (Mykrox, Zaroxolyn), indapamide (Lozol), and others;

  • diabetes medications such as glipizide (Glucotrol), tolbutamide (Orinase), and others;

  • anticoagulants (blood thinners) such as warfarin (Coumadin);

  • other cholesterol treatments such as gemfibrozil (Lopid), clofibrate (Atromid-S), and nicotinic acid (niacin);

  • thyroid hormones such as levothyroxine (Synthroid, Levoxyl, Levothroid);

  • medicines used to treat depression such as imipramine (Tofranil);

  • gallstone medications such as ursodiol (Actigall);

  • seizure medicines such as phenytoin (Dilantin);

  • fat-soluble vitamins such as vitamins A, D, E, and K (you may require vitamin supplements); and

  • steroid drugs such as hydrocortisone (Cortef, Hydrocortone).

Drugs other than those listed here may also interact with colestipol. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

What happens if I have an overdose of colestipol?

Seek emergency medical attention.

Symptoms of a colestipol overdose include abdominal pain, constipation, flatulence, and an intestinal blockage.

Find more results for 'Colestid'
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Content provided by Multum - Last Updated 2/11/2008