SILODOSIN - ORAL
Common Brand Name(s): Rapaflo
Phonetic Pronunciation: (SIL-oh-DOE-sin)
Information last revised May 2010
What does SILODOSIN - ORAL look like?
Rapaflo 4 mg Cap
Rapaflo 8 mg Cap
Uses:
This medication is used to treat the symptoms of a prostate gland condition called BPH (benign prostatic hyperplasia, also known as an enlarged prostate). Silodosin is an alpha-blocker that works by relaxing the muscles in the bladder neck and prostate. Relaxing these muscles leads to relief of symptoms of BPH such as the feeling of needing to urinate frequently or urgently, weak stream, difficulty in beginning the flow of urine, and the need to urinate during the middle of the night. Silodosin does not shrink the prostate. This medication should not be used to treat high blood pressure.
Missed Dose
If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
How To Use
Take this medication by mouth, usually once a day with a meal, or as directed by your doctor. Ask your doctor if you should take the first dose at bedtime to minimize the chances of getting dizzy or fainting. After the first dose, take your regularly scheduled dose with the same meal each day, or take exactly as directed by your doctor. The dosage is based on your medical condition and response to treatment. Use this medication regularly in order to get the most benefit from it. To help you remember, take it at the same time each day. Inform your doctor if your symptoms do not improve or if they worsen.
Drug Interactions
Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first. This drug should not be used with the following medications because very serious interactions may occur: drugs that strongly affect the removal of silodosin from your body (including clarithromycin, ritonavir, azole antifungals such as itraconazole/ketoconazole). If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting silodosin. Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: other alpha-blocker drugs (such as doxazosin, prazosin), drugs for high blood pressure, drugs for male erectile problems (such as sildenafil, tadalafil, vardenafil), other drugs that affect the removal of silodosin from your body (such as cyclosporine, diltiazem, erythromycin, fluconazole, verapamil, St John's wort). Check the labels on all your medicines (such as antihistamines including diphenhydramine) because they may contain ingredients that cause dizziness or urinary problems. Ask your pharmacist about the safe use of those products. This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.
Notes
Do not share this medication with others. Keep all medical appointments. Laboratory and/or medical tests (such as blood pressure, prostate exams including prostate-specific antigen or PSA) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.
Overdose
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canadian residents can call a provincial poison control center.
Precautions
Before taking silodosin, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, low blood pressure/fainting. To avoid dizziness or fainting, get up slowly from a lying or seated position, especially when you first start taking this drug or if your doctor changes your dosing. Also, when you first start taking this drug, avoid situations where you may be injured if you faint. This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages. Before having cataract surgery, tell your doctor that you are taking this medication of if you have ever taken it. Before having any surgery, tell your doctor or dentist that you are taking this medication. Caution is advised when using this drug in the elderly because they may be more sensitive to the effects of this drug, especially dizziness. This medication is not recommended for use in women or children.
Storage
Store at room temperature at 77 degrees F (25 degrees C) away from light and moisture. Brief storage between 59-86 degrees F (15-30 degrees C) is permitted. Do not store in the bathroom. Keep all medicines away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.
Side Effects
Dizziness or problems ejaculating may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor immediately if any of these rare but serious side effects occur: fainting, vision changes. In the unlikely event you have a painful or prolonged erection lasting 4 or more hours, stop using this drug and seek immediate medical attention, or permanent problems could occur. A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.
The information contained in the First DataBank databases is intended to supplement the knowledge of physicians, pharmacists, and other healthcare professionals regarding drug therapy problems and patient counselling information. This information is advisory only and is not intended to replace sound clinical judgment in the delivery of healthcare services. First DataBank disclaims all warranties, whether expressed or implied, including any warranty as to the quality, accuracy, and suitability of this information for any purpose.
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