What is theophylline?
Theophylline is a bronchodilator. It works by relaxing muscles in the lungs and chest, and makes
the lungs less sensitive to allergens and other causes of bronchospasm.
Theophylline is used to treat the symptoms of asthma, bronchitis and emphysema.
Theophylline may also be used for other purposes not listed in this medication guide.
What should I discuss with my healthcare provider before taking theophylline?
Do not use this medication if you are allergic to theophylline.
Before taking theophylline, tell your doctor if you are allergic to any drugs, or if you have:
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a stomach ulcer;
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epilepsy or other seizure disorder;
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a heart rhythm problem;
-
congestive heart failure;
-
fluid in your lungs;
-
underactive thyroid;
-
a high fever;
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liver disease (such as cirrhosis or hepatitis);
-
kidney disease; or
-
if you have recently quit smoking cigarettes or marijuana.
If you have any of these conditions, you may need a dose adjustment or
special tests to safely take theophylline.
FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your
doctor if you are pregnant or plan to become pregnant during treatment.
Theophylline can pass into breast milk and may harm a nursing baby. Do not use this
medication without telling your doctor if you are breast-feeding a baby.
Older adults may be more likely to have side effects from theophylline.
How should I take theophylline?
Take this medication exactly as it was prescribed for you. Do not take the medication in larger
amounts, or take it for longer than recommended by your doctor. Follow the directions on your
prescription label.
Your doctor may occasionally change your dose to make sure you get the best results from this
medication.
Take this medicine with a full glass of water.
You may take theophylline with or without food, but take it the same way every time.
Do not crush, chew, break, or open an
extended-release
tablet or
capsule unless your doctor tells you to. Swallow the pill whole. It is specially made to release medicine
slowly in the body. Breaking or opening the pill would cause too much of the drug to be released at
one time.
Your doctor may tell you to break a regular theophylline tablet before you take it. Some tablets
have special scored marks on them to make breaking the tablet easier. Follow your doctor's
instructions.
Measure the liquid form of theophylline with a special dose-measuring spoon or cup, not a
regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.
If there are any changes in the brand, strength, or type of theophylline you use, your dosage
needs may change. Always check your medicine when it is refilled to make sure you have received the
correct brand and type as prescribed by your doctor. Ask the pharmacist if you have any questions
about the medicine you receive at the pharmacy.
Do not start or stop smoking without first talking to your doctor. Smoking changes the way
your body uses theophylline, and you may need to use a different dose.
Store theophylline at room temperature, away from moisture, heat, and light.
What happens if I miss a dose of theophylline?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the
missed dose and take the medicine at your next regularly scheduled time.
Do not
take
extra medicine to make up the missed dose.
Where can I get more information about theophylline?
Your pharmacist has information about theophylline written for health professionals that you may read.
What are the possible side effects of theophylline?
Get emergency medical help if you have any of these
signs of an allergic
reaction:
hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using theophylline and call your doctor at once if you have any of these serious side
effects:
-
seizure (convulsions);
-
worsening of your condition, or symptoms of new illness;
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severe or ongoing nausea and vomiting, headache, fast or
uneven heart rate, and trouble sleeping (insomnia);
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coughing up blood or vomit that looks like coffee grounds;
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ongoing fever;
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feeling restless, irritable, nervous, or jittery.
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tremors; or
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urinating more than usual.
Less serious side effects may include:
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mild nausea, loss of appetite, weight loss;
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restlessness, tremor, or insomnia; or
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headache, lightheadedness, or dizziness.
This is not a complete list of side effects and others may occur. Call your
doctor for medical advice about side effects. You may report side effects to FDA at
1-800-FDA-1088. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about theophylline?
If there are any changes in the brand, strength, or type of theophylline you use, your dosage
needs may change. Always check your medicine when it is refilled to make sure you have received the
correct brand and type as prescribed by your doctor. Ask the pharmacist if you have any questions
about the medicine you receive at the pharmacy.
Do not start or stop smoking without first talking to your doctor. Smoking changes the way
your body uses theophylline, and you may need to use a different dose.
Avoid drinks or foods that contain caffeine, such as coffee, tea, cola, and chocolate.
Caffeine may increase some of the side effects of theophylline.
There are many other medicines that can interact with theophylline.
Tell your doctor about all the prescription and over-the-counter medications you use. This includes
vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new
medication without telling your doctor. Keep a list with you of all the medicines you use and show this
list to any doctor or other healthcare provider who treats you.
What should I avoid while taking theophylline?
Theophylline can cause side effects that may impair your thinking or reactions. Be careful if
you drive or do anything that requires you to be awake and alert.
Avoid drinks or foods that contain caffeine, such as coffee, tea, cola, and chocolate.
Caffeine may increase some of the side effects of theophylline.
What other drugs will affect theophylline?
Before taking theophylline, tell your doctor if you are using any of the following drugs:
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carbamazepine (Carbatrol, Tegretol);
-
cimetidine (Tagamet);
-
enoxacin (Penetrex);
-
ephedrine or similar medications found in cold medicine or
diet pills;
-
erythromycin (E.E.S., E-Mycin, Ery-Tab);
-
fluvoxamine (Luvox);
-
propranolol (Inderal, InnoPran);
-
rifampin (Rifadin, Rifater, Rifamate, Rimactane);
-
St. John's wort; or
-
thiabendazole (Mintezol).
This list is not complete and there are many other medicines
that can interact with theophylline.
Tell your doctor about all the prescription and
over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs
prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a
list with you of all the medicines you use and show this list to any doctor or other healthcare provider
who treats you.
What happens if I have an overdose of theophylline?