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The harmful ingredients are contained in the cigarette, chew, cigar, etc... they include: tar, carbon monoxide and other cancer causing chemicals.. Hope that helps!
also, I have been on ULTRAM for chronice Neouropathic pain, and have now switched to elavil and Neourontin.. They are working great! I don't feel like a zombie anymore, and rarely take the Ultram* anymore.
Feeling GREAT in the Midwest-- Jess
*the withdrawl from ULTRAM was the worst withdrawl I've EVER experienced... Use it with CAUTION if it is prescribed to you!