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Ryan, sounds like you know your stuff! One beta blocker you left out though that I've taken for years with no side effects (in lower doses) is Sectral (acebutolol). 200 mg twiceTwice-a-day a day. I'm now at 400 morning & 200 mg night. But it has done the best for me as far as no side effects. I also take KlonopinKlonopin Klonopin wafer when needed for PVCs- -when that adrenalinCatecholamines - blood just gets too excited!
Have you ever tried or heard good results from Lexapro to prevent adrenalin rushes? Although I'm not depressed my internal dr. thought it might raise my serotonin level & give my total body a less sensitive nervous system. - - to lower the PVCs. What do you think
Are you on any anti-anxiety medicine?
Long-term use of beta-blockers carries a few risks, but ultimately, they are quite safe.
Risks:
-Development of type II diabetes
-Development of autoimmune and vascular disorders (Raynaud's), and positive ANA finding
-Development of Asthma (for non-selective beta-blockers)
-Loss of sympathetic stimulation and heart failure (extremely rare)
-1st degree heart block or mild bradycardia (pulse slightly lower than 60 bpm at rest)
-Loss of exercise tolerance (due to lowered pulse)
-Weight gain
-Dependency
For anxiety and control over the autonomic nervous system, the non-selective beta-blockers work better than the cardio-selective types, as they target all beta receptors.
Inderal (Propranolol), Corgard (Nadolol), Coreg, and Blocadren (Timolol) are examples of non-selective beta-blockers. These have a wider side effect profile.
Tenormin (Atenolol) and Toprol (Metoprolol) are examples of cardio-selective beta-blockers. These have less side effects, as they chiefly target the myocardium.
If you suffer from many cardiac manifestations of anxiety (palpitations, premature beats, extrasystoles, bounding pulse, tachycardia, elevated BP), a combination of a non-selective beta-blocker (such as Inderal) and a Benzodiazepine (such as Klonopin) will help tremendously. Typical starting doses are 20 mg BID for the Inderal, and 1/2 mg BID for the Klonopin. The two drugs not only prevent recurring attacks, but work in concert to decrease autonomic hyperactivity when an attack does occur.
-Ryan
Read some books on Panic also. Claire Weekes is a great author. You really must be active in your own recovery. You can do it!!
Your problem is most likely: HYPERCOAGULABLE STATE, which predisposes you to embolic type phenomena (recurring headaches) and an elevated risk of venous thrombosis. Anxiety usually presents secondary to this disorder. Tachy blood would also result in the cardiac manifestations that you mention, and would occur in paroxysms (attacks).
The elevated Hemoglobin and Hematocrit confirms the diagnosis. I would also suggest the following work-up (to be performed by a Hematologist), as this work-up will narrow down exactly which disorder you have:
-Factor X
-Protein C
-Protein S
-Antithrombin III
-Anticardiolipin IGM, IGG
-APC Resistance
-Prothrombin Gene Variant
-MTHFR Gene Variant A1298C
-Hemochromotosis Gene Variant C2827
-Hexagonal Lipid Neutralization
-Homocysteine Level
-Platelet Aggregation Studies
-Prothrombin Time, INR
-Ferritin Level
-Antinuclear Antibody