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Breast Cancer  (Expert Forum)
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After surgery Chemo / radiation / nothing require
Questions posted in the Breast Cancer Forum are answered by medical professionals from The Cleveland Clinic. Topics include Breast Biopsy, Chemotherapy, Hormone Therapy, Lumps, Lumpectomy, Lymph node dissection, Lymphedema, Mammograms, Mastectomy, Radiation Therapy, Reconstruction, Self Breast Exam, and Surgery.

After surgery Chemo / radiation / nothing require

by Shahworld, Sep 15, 2005 12:00AM
Base on following after surgery Histo report what after surgery treatment [Eg. Chemo / radiation] is require to ensure 100% clearance?



Histo pathology report

Received a specimen of needle localized right breast lumpectomy measuring 12.5 X 11 X 4.5 cm with a skin ellipse measuring 1.5 cm. On serial section & subsequent mammography, of micro calcification are identified. Grossly the corresponding area revel presence of an ill define firm white. Lesion measuring 1.6 X 1 X cm. Representative sections from this areas are submitted. Over line skin & abjection breast are grossly unremarkable.



Various cut margins are

Superior cut margin: 2.8 cm

Inferior CM: 2.2 cm

Medical cut margin: 3.8 cm

Lateral cut margin: 3.0 cm

Anterior cut margin: 1.2 cm

Posterior cut margin: 1.0 cm



Away from wide area

Also received axilla 14 node are dissected. Largest measuring 1.4 cm in diameter.  Grossly unremarkable.

Apical nodes : single node dissected: 08 cm. In diameter grossly unremarkable.



Microscopic description.

Right breast lumpectomy:



= Multiple section taken from areas corresponding to mammography micro calcification show extensive cormedo pre cribiform DCIS of high nuclear grade with a small focus of infiltrating duct carcinoma, grade – III.



= Modified R.B. score = 3 + 3+ 2 = 8.



= EIC is seen



= All cut margins are free of tumor.



= Axillaries node: 14 Reactive nodes



= Apical Node: Single negative node



= ER – negative



Base on above after surgery Histo report what after surgery treatment[Eg. Chemo / radiation] is require to ensure 100% clearance?

by CCF-RN,MSN-rf, Sep 15, 2005 12:00AM
Dear shahworld:  There is NO therapy that can provide 100% guarantee that there will not be a recurrence.  There are no 100%guarantees in medicine in general - only statistically calculated risks and benefits that must be considered with each individual case with the person's physician.  In general, if a person has had a lumpectomy for invasive breast cancer, radiation therapy will likely be recommended.  The decision to do chemotherapy will depend upon the size of the invasive component of the cancer, the status of the lymph nodes, and the health of the patient, among other variables.  These decisions are best determined by a medical oncologist who has reviewed the information and met with the patient - to do a history and physical examination.  In this case, there should be a discussion with the patient's medical oncologist.  If there is concern, a second opinion is always an option.

Member Comments (1)

by amanda963, Apr 22, 2008 01:50PM
A related discussion, After Treatment tests was started.
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