We are not pharmacists or physicians on this website, but I do have a suggestion for you. Please call your local pharmacist and ask if hypoglycemia can be a side effect of either of these meds or of taking both at the same time.

I did find this on the web about Wellbutrin:
'Wellbutrin is indicated for the treatment of depression. A doctor considering this as a first-line defense for an initial episode of depression should be aware that the drug may cause generalized seizures in a dose-dependent in some patients. The incidence of seizures may exceed that of other antidepressants by as much as four-fold. The relative risk is only an approximate estimate because no comparative studies have been conducted.'

So whether your seizure (which is what it appears you had if you were bouncing in the bed) was caused by low blood sugar or by the Wellbutrin, it may be hard to know for sure.

I would certainly call my doctor after talking to pharmacists and discuss the dangers of taking Ambien as a type 1 diabetic. It is absolutely CRUCIAL that you are able to wake up if your blood glucose gets too low. I personally would never take a sleep aid as a type 1 diabetic (this is of course my own personal opinion) -- night-time hypoglycemia can be very dangerous, even deadly. Better to find some other way to ensure a good night's sleep than to perhaps put you under so deeply that your body can't wake you up if you get hypoglycemic at night. It seems very possible that this medication may have made it impossible for you to wake up when your glucose dropped as you slept. You are very fortunate that your husband woke up to help you.

Do call your doctor and discuss the meds with him. I personally know how terrifying night lows can be, and I avoid them at all costs these days. I do wish you the best.

I just started Wellbutrin today and I have crashed twice already. I have had my normal meals with well-tested boluses, so I do think the Wellbutrin is reducing my insulin requirements.