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Family Medicine  (Expert Forum)
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Abnormalities in CBC/Iron Tests
Answered by
Kevin Pho, MD - Internal Medicine
Kevin Pho, MD Boston - MA
Questions in the Family Medicine forum are answered by Dr. J.M. Keyes. Topics covered include general health issues, adolescence, babies, child health, eating disorders, fitness, immunizations and vaccines, infectious diseases, medical tests and procedures, and senior health.

Abnormalities in CBC/Iron Tests

by mar81067, Jan 12, 2007 12:00AM
Can you explain what the possible reasons would be for the abnormalities shown in these test results of a 39 year old female?  Can you recommend any further tests required to determine the reason for the abnormalities?



I donate blood every 2 months and I take 81 mg of aspirin once a day.



Test Result Range

WBC 6.4 K/uL 4-10 K/uL

LYM 1.8 28    %L 1.1 - 4.2 28-42 %L

MID 0.5 7.1   %M 0.0 - 1.2 0-12  %M

GRAN 4.2 R3 64.9  %G        1.8 - 6.3 46-63 %G



RBC 5.15 M/uL 4.2 - 5.4 M/uL

HGB 12.8 g/dL 12 - 16 g/dL

HCT 39.3 % 37 - 47%

MCV           * 76.4 fL 81 - 101 fL

MCH       * 24.9 pg 27 - 34 pg

MCHC 32.6 g/dL 31.5 - 36 g/dL

RDW       * 19.5 % 12 - 14%



PLT 299 K/uL 140 - 440 K/uL



Iron, Total 104 35 - 175 MCG/DL

Iron Binding Cap      * 449 250 - 400 MCG/DL

% Saturation 23 15 - 50%

Ferritin       * 9 10-154 NG/ML



Hemoglobin A1 97.9 >96%

Hemoglobin F <1 <2%

Hemoglobin A2 2.1 1.8-3.5%

by Kevin Pho, MD, Jan 13, 2007 12:00AM
The low MCV, ferritin, along with elevated TIBC (binding capacity) are consistent with iron deficiency anemia.  



Heavy periods can lead to this.  If the problem is not GYN-related, I would consider a GI workup (i.e. a colonoscopy) to evaluate the symptoms.  



You can discuss these options with your gynecologist, or consider a referral to a gastroenterologist.



I would also consider iron supplementation.



Followup with your personal physician is essential.



This answer is not intended as and does not substitute for medical advice - the information presented is for patient education only. Please see your personal physician for further evaluation of your individual case.



Kevin, M.D.

kevinmd_
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