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Fertility / Infertility (Expert Forum)
Miscarriage rates over 35
Questions in the Fertility/Infertility forum are answered by doctors affiliated with USF Health. Topics covered include fertility or infertility issues, egg quality, fertility drugs and side effects, fertility tests, genetic testing, in-vitro fertilization (IVF), ovulation, relationship issues, risk factors, sperm count/quality, and surgery.
Miscarriage rates over 35
by waiting4ever, Jun 02, 2007 12:00AM
I am 37 and have just had my second m/c in a year with IVF. These were both FET cycles, and ended between 8 and 10 weeks. Does that make a difference? We have been using donor eggs as well. Donor was 30 when eggs were retreived.
We still have 3 embryos left and have decided to give it one last try. What are our chances for success? Is there something we can do to help prevent another m/c? Since I have Endometriosis, I have been thinking that this may have been a factor as well.
We still have 3 embryos left and have decided to give it one last try. What are our chances for success? Is there something we can do to help prevent another m/c? Since I have Endometriosis, I have been thinking that this may have been a factor as well.
Doctor's Answer
by Forum-M.D.-JM, Jun 02, 2007 12:00AM
My first question would be why donor eggs at 37, I can only assume premature ovarian failure. And I assume the fresh donor egg cycle was negative and then came the 2 FET pregnancies with the donor eggs that miscarried. First the success in 2 FET pregnacies, maybe not the outcome, but this is a positive. FET pregnancies are against the odds in the 30 to 40 % range of achieving a pregnancy at all and it happened twice.
Second the number one reason for miscarriage is genetics, with a 30 year old donor the miscariage rate is equal to the general population 30%. It is the age of the egg NOT the uterus for the high genetic component to miscarriages.
Two pregnancy loss with 30 year old eggs between 8 and 10 weeks, I would start looking at a diagnosis of recurrent habitual abortions. There are a variety of reason for RHA, recurrent miscarriages and it maybe that some of these should be looked at. But keeping in mind that FET does have a lower take home baby rate than fresh cycles.
Hope it helps,
JM
Second the number one reason for miscarriage is genetics, with a 30 year old donor the miscariage rate is equal to the general population 30%. It is the age of the egg NOT the uterus for the high genetic component to miscarriages.
Two pregnancy loss with 30 year old eggs between 8 and 10 weeks, I would start looking at a diagnosis of recurrent habitual abortions. There are a variety of reason for RHA, recurrent miscarriages and it maybe that some of these should be looked at. But keeping in mind that FET does have a lower take home baby rate than fresh cycles.
Hope it helps,
JM
Member Comments (2)
by thecptswife, Jun 16, 2007 12:00AM
To: IVF over 40
My second husband and I would like to have a child. But, I had my tubes tied after my son was born 8 1/2 years ago. The only doctor in town that does IVF says he will not do it if a woman is over 40. I'm almost 42, but young looking and young at heart. I don't smoke, don't have high blood pressure, etc. I was wondering if there is anyone who might have had IVF after 40 and what they experienced. Or, if anyone has any advice, please help. Thank you.
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