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MTHFR (Methylenetetrahydrofolate reductase) Group

This Group was created for anyone wishing to learn, chat or share information relating to MTHFR. Many woman have suffered Miscarriage(s) and have no idea why. For some of us, a genetic mutation called MTHFR is the reason. MTHFR (or 5,10-methylenetetrahydrofolate reductase NADPH) is a genetic mutation that has 24 known variants that affects the ability to absorb Folic Acid and can cause more severe problems in health and also in pregnancy. There is much debate and dispute within the medical community regarding MTHFR and it's relationship to pregnancy loss or Recurrent Pregnancy Loss (RPL). In all the confusion, there are many ideas and treatments along with schools of thought on how to treat or deal with MTHFR.

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1227139_tn?1367231533
Welcome to everyone - new and existing members! If you are new here, please introduce yourself and tell us a bit about why you are here. This group was created for anyone who may have received a diagnosis of MTHFR, anyone dealing with ...
Dragon1973 | Last answer
1227139_tn?1367231533
What is MTHFR? MTHFR is the scientific name for Methylenetetrahydrofolate reductase. It is also the gene that provides the body with instructions on how to make an enzyme called methylenetetrahydrofolate reductase. When one has a gen...
Dragon1973 | Posted
1227139_tn?1367231533
Here is the majority of the information available in one document. I hope if you have been recently diagnosed this proves to be an effective aide to provide your health care provider(s). MTHFR Gene Mutation What is it? The gen...
Dragon1973 | Last answer
Avatar_universal
Women who experience multiple miscarriages are more likely to have MTHFR gene mutation, though researchers have not established a direct, causal relationship between the two. It is believed that such mutations can sometimes cause blood c...
macejaran | Posted
Avatar_universal
Hi all, I’ve just got my 23andme interpretation from Genetic Genie as was wondering if anyone had any thoughts on treatments and potential issues. I’m pretty much a newbie when it comes to MTHFR. I’ve had 10 years of symptoms which ar...
adey124 | Posted
Avatar_universal
For years I have suffered from joint aches, muscle aches, headaches, burning skin, numbness, fatigue,skin rashs and stomach problems. Ive been tested for every thing like lupus and m.s. I was recently tested for the mthfr and came back ...
bellxxxx | Posted
Avatar_universal
For years I have suffered from joint aches, muscle aches, headaches, burning skin, numbness, fatigue,skin rashs and stomach problems. Ive been tested for every thing like lupus and m.s. I was recently tested for the mthfr and came back ...
bellxxxx | Posted
1227139_tn?1367231533
Hi everyone, I thought I would start off by introducing myself and my genetic mutation variant C677T. While C677T is one of the two common MTHFR variants it is the most problematic of the variants because of its relationship to clot...
Dragon1973 | Last answer
Avatar_universal
Hello, I was just told I have a MTHFR gene mutation. Can anyone help me to understand why I would also have high iron levels? My doctor told me to stay away from red meat and vitamin C. And, I am taking Vitamin D, Vitamin B12 and I wa...
Betzine | Posted
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Just wondering I see a lot of old posts and most of them with no responses or answers. Does anyone come on here anymore? I have a few questions.
Echo30 | Posted
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Please help. I am in the Charlotte, NC area and need to find doctors who fully understand how to treat MTHFR. I'm trying to conceive and have had fertility issues that I believe are related to MTHFR, but the RE I saw dismissed the connec...
Waitingcrib | Posted
1227139_tn?1367231533
Well, as I have posted, there are 24 known MTHFR variants and two that are most common in our population. C677T and A1298C are the most common variants but there are others and ones yet to be discovered. I am curious which variants eve...
Dragon1973 | Last answer
175861_tn?1428186013
The one I have is c677t heterozygous. I've had a lot of weird symptoms--shaking, tingling, anxiety, a caffeinated feeling (but having no caffeine). Right now my hands and arms are tingling and it hurts. Is this due to the neurotransmit...
phix95 | Last answer
Avatar_universal
My family member has had a 2 year+ headache. It ranges from moderate(rarely) to more severe (frequently). We are doctoring at a Headache Clinic, but still have few functional days. We have also done alternative treatments, supplements,...
Avatar_universal
Does anyone know of a way to find doctors that can diagnose and treat MTHFR mutations? Specifically, I have relatives in Wisconsin, and people I know in Canada and Tennessee that are looking for doctors to help them with the testing and ...
AZGirl1007 | Last answer
Avatar_universal
I am positive for one copy of the C677T mutation and one copy of the A1298C mutation. My doctor put me on Lovenox on day one of a positive pregnancy test and Folbee Plus (daily). I had several early miscarriages but after starting the Lo...
Xlynnex | Posted
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Hi, I was told yesterday to start a low dose aspirin a day. The doctor said I have the mthfr and he felt it was causing some of my problems. I also have celiac sprue so that does not help as my levels are all to low. I take 5000 iu of...
grandma080910 | Posted
Avatar_universal
Can blacking out be a cause from high PMT/ inr levels
careywaters | Posted
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Three years ago i was told that i had two Mthfr mutations, Homozygous. I just found out that I'mpregnant and I'mgoing to a different dr then before. I told him about the Mthfr mutation and he did blood work and it came Back today. One of...
mami2alex | Posted
Avatar_universal
I am 24 year old. I have an almost 4 year old daughter. A year after she was born I had a m/c due to anencephaly and leter found out I tested pos. For homozygous myhfr. About six months later I got pregnant again and at 20 weeks found ou...
mami2alex | Posted
Avatar_universal
I Found out 2 years ago that I was positive with MTHFR,I didn't have insurance then but now I do.I will be going to see a hemotologist in two weeks. I am 46, and have had two miscarriages in my life, and am on coumadin for life due to ha...
Nayann6446 | Posted
Avatar_universal
I have mthfr c667t homozygous and pai-1. Just wondering if anybody is on treatment and not pregnant. I was pregnant and on many multivitiamins, aspirin and lovenox. I think I should still be on aspirin and folic acid at least. Hematologi...
nancy1122 | Posted
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