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Mental Health  (Expert Forum)
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Anyone know anything about effectiveness of Lamictal?
Questions posted in the Mental Health forum are being answered by Dr. Roger L. Gould, author of the Mastering Stress and Depression program and affiliated with the UCLA. Department of Psychiatry. Topics covered include anger, attention deficit disorder (ADD), bipolar disorder, dementia, electroconvulsive therapy (ECT), learning disabilities, memory, obsessive compulsive disorder (OCD), panic, personality disorders, phobias, post-traumatic stress disorder (PTSD), schizophrenia, stress, transitions, and work problems.

Anyone know anything about effectiveness of Lamictal?

by Chase Miller, Oct 14, 1999 12:00AM
I am already on 75 mg. of Effexor and my psychotherapist has recommended lamictal, even though I am unipolar.  Would be interested in hearing others' comments.

by HFHS M.D.-SW, Oct 18, 1999 12:00AM
Dear Will,



Effexor is an effective treatment for major depression in the majority of sufferers. The effective dose of the XR preparation may be up to 300 mg a day.

Lamictal is an anti convulsant and has not been approved for use to treatment of Major Depression, although there is ongoing research examining its use in bipolar disorder.

Some case reports had been published recently for its efficacy to treat bipolar disorder symptoms - mania and depression. There has not been evidence to support its use in Major Depressive Disorder.

I recommend your psychiatrist increase your dose of Effexor, unless your are having disturbing side effects, prior to changing or adding medications.

There are more logical options with good research to back them, than the use of Lamictal in major depression.



Sincerely,



HFHS M.D.-SW



*Keywords: Lamictal, Bipolar, Effexor, Depression
Member Comments (2)

by chris, Oct 17, 1999 12:00AM
Hi Will



Until a few days ago I was on Effexor 375mgs but my psychiatrist had me stop it and wants me to try Lamictal.  I will be starting this drug within a couple of days.  I will also remain on Wellbutrin 300mgs and Remeron 60 mgs.  I posted a question recently about Lamictal and the reply was that Lamictal was not approved by the FDA for unipolar depression just bi-polar.  I would be interested in hearing what you think about Lamictal.  All I know is that there is a potential rash that can appear while taking Lamictal and that it must be started at a very low dose and gradually increased until there is improvement in depression. Feel free to write to me.  Chris  (***@****)
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