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Mental Health (Expert Forum)
What is the most sedating, newer Antidepressant?
Questions posted in the Mental Health forum are being answered by Dr. Roger L. Gould, author of the Mastering Stress and Depression program and affiliated with the UCLA. Department of Psychiatry. Topics covered include anger, attention deficit disorder (ADD), bipolar disorder, dementia, electroconvulsive therapy (ECT), learning disabilities, memory, obsessive compulsive disorder (OCD), panic, personality disorders, phobias, post-traumatic stress disorder (PTSD), schizophrenia, stress, transitions, and work problems.
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What is the most sedating, newer Antidepressant?
by Chase Miller, Nov 24, 1999 12:00AM
I have problems with panic attacks and have tried Buspar and Effexor. I asked my doctor which of the newer antidepressants was the most sedating. She said that they all make claims to be; however, she didn't know. She stated that among the older ones (tricyclics), Imipramine, was the best for sedation. I don't want to increase my heart rate and am looking for one of the newer ones. Any suggestions? Have heard that Serzone is a good one, true? Thanks.
Doctor's Answer
by HFHS.MD-AJ, Nov 28, 1999 12:00AM
Doug,
Remeron and Serzone would appear to be the most sedating new antidepressants available. However, neither medication has been clearly shown to be effective in treating panic disorder, although there are a few reports supporting this. There are more consistent studies supporting treatment of panic disorder with the SSRIs (Paxil, Zoloft, Celexa, Prozac), Effexor, or benzodiazepines (Xanax, Klonopin, Ativan). Paxil probably has the most sedative effects among the SSRIs. Buspar may have a role in the augmentation of other medications, but has not been proven to be effective for treatment of panic disorder by itself. There are studies which suggest that panic disorder is best treated with a combination of medications and cognitive-behavioral therapy.
I urge you to seek consultation with a psychiatrist who is familiar with these medications, if you are not under the care of one yet.
Remeron and Serzone would appear to be the most sedating new antidepressants available. However, neither medication has been clearly shown to be effective in treating panic disorder, although there are a few reports supporting this. There are more consistent studies supporting treatment of panic disorder with the SSRIs (Paxil, Zoloft, Celexa, Prozac), Effexor, or benzodiazepines (Xanax, Klonopin, Ativan). Paxil probably has the most sedative effects among the SSRIs. Buspar may have a role in the augmentation of other medications, but has not been proven to be effective for treatment of panic disorder by itself. There are studies which suggest that panic disorder is best treated with a combination of medications and cognitive-behavioral therapy.
I urge you to seek consultation with a psychiatrist who is familiar with these medications, if you are not under the care of one yet.
Member Comments (1)
by DIngo, Dec 09, 1999 12:00AM
serzone stinks, hass too many side effects
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