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Mental Health  (Expert Forum)
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Luvox and seizures
Answered by
Roger Gould, M.D. - Mental Health, Wellness
Questions posted in the Mental Health forum are being answered by Dr. Roger L. Gould, author of the Mastering Stress and Depression program and affiliated with the UCLA. Department of Psychiatry. Topics covered include anger, attention deficit disorder (ADD), bipolar disorder, dementia, electroconvulsive therapy (ECT), learning disabilities, memory, obsessive compulsive disorder (OCD), panic, personality disorders, phobias, post-traumatic stress disorder (PTSD), schizophrenia, stress, transitions, and work problems.

Luvox and seizures

by KatieDee, Oct 22, 2001 12:00AM
My 8 yr. old son has epilepsy and Tourettes.  He was recently given Luvox 25 mg b.i.d.  He took this for two weeks for OCD, but I noticed that he had a lot of bruises appear - legs, arms, stomach.  The psychiatrist said to stop the Luvox as it may be related to the bruising.  He was on no other med, no AED as his neuro had stopped his AED in August to see if seizures returned since he hadn't had any since about April.  The first day he had no Luvox he had a complex partial seizure.  The following day he had 10 seizures and ended up in the ER to be given IV Dilantin.  My question is this, could Luvox have lowered his seizure threshold and could it have caused the easy bruising?  If so, would that mean he would be unable to take other SSRI's for his OCD?  I should mention that his bloodwork taken two days after stopping the Luvox showed his creatinine, bilirubin and alkaline phos were out of range on the low end.  It also showed his WBC and neut % to be out of range on the high end.  No mention was made of this by the ER doc, but I wonder if this is Luvox-related or maybe he just had some kind of minor infection.



Thank You

by Roger Gould, M.D., Oct 22, 2001 12:00AM
This is a complex case because of the seizure issues and your neurologist is the best one to guide you here. When you read the fine print on Luvox and other ssri's, you see that this kind of reaction is possible, but very difficult to prove. It doesn't meant that it will happen again, so cautious re-trial of a ssri could be done under medical supervision.
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