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Mental Health  (Expert Forum)
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Celexa and Memory Loss
Answered by
Roger Gould, M.D. - Mental Health, Wellness
Questions posted in the Mental Health forum are being answered by Dr. Roger L. Gould, author of the Mastering Stress and Depression program and affiliated with the UCLA. Department of Psychiatry. Topics covered include anger, attention deficit disorder (ADD), bipolar disorder, dementia, electroconvulsive therapy (ECT), learning disabilities, memory, obsessive compulsive disorder (OCD), panic, personality disorders, phobias, post-traumatic stress disorder (PTSD), schizophrenia, stress, transitions, and work problems.

Celexa and Memory Loss

by T Mack, Jan 31, 2003 12:00AM
For a long time I have suffered from mild social anxiety, but not depression.  It tends to come and go mostly based on factors such as whether or not I’ve been getting enough sleep, but in any case about 2 ˝ years ago I started taking Paxil, which worked moderately well but I stopped due to the sexual side affects and slight memory loss.  I then started taking Celexa.  The Celexa worked much better and helped to improve my life but I started to have distinct memory loss as a result of the medication.  I started cutting back and would usually take only one or two 20 Mg. doses a week, but I still was feeling the negative affects.  I was hesitant to get off of it completely because overall I was still happier on it, but I am now worried that I might cause myself permanent memory loss (brain damage??) if I continue on the drug.  A few weeks ago I went back into my doctor and he prescribed Zoloft which I have been taking but have not noticed any positive affects yet, and my memory has not seemed to improve.



Do you think there is a chance that I have caused or may eventually cause permanent damage to my brain?  I read another account on the web from a former Celexa user with a similar story who stated she still has not regained her full mental sharpness since stopping the drug.  Do you know whether Lexapro could help neutralize the side affects of the memory loss?  Is there some sort of herb or medication that could counter the memory loss I am experiencing?  Would it be possible that I would have this reaction to all SSRI's?  Can you recommend a doctor that might specialize in this type of thing in the San Francisco area?  I'd really love to find something with the benefits of Celexa but without the memory loss.  Thank you.

by Roger Gould, M.D., Jan 31, 2003 12:00AM
Lexpro is suppose to be the medication you are looking for. I would look into that, but first you should consult a psychopharmacologist in your area.  I would suggest that you call the university medical center, department of psychiatry, and ask for a referral to one of their faculty or graduates.  

That is the best way.
Member Comments (1)

by writepooh7, Feb 21, 2003 12:00AM
Hi have been taking celexa scnece my brother passed on three yrs ago and had a baby  A couple weeks before he died.. I have had alot of forgetful ness in the last 6 mo?

by anthrogirl, Feb 26, 2003 12:00AM
I have experianced some memory loss while being on celexa.  But my biggest side affect is how sleepy it makes me.  I feel tired almost all of the day.  I decided to try and go off celexa on my own (I am on 20 mg.) but after about 4 days of being off Celexa, I started getting VERY dizzy, and had a constant disconnected feeling.  I started taking my dose again, and those sypmtoms went away.  I have another 3 months to go before I see my doctor again, so I've decided to stay on celexa until he tells me the proper way to ween down.  I was unaware of how much the body goes through withdraw with Celexa.

by Baadsie, Apr 28, 2003 12:00AM
Lexapro is supposed to be a refined version of Celexa, unfortunately you will find that it will have all the same side-effects as celexa or any of the other SSRI's. What you need to do is to have a simple enzyme test for the enzyme P450. If you have low or no P450 enzymes then you body with no metablize the medication and will have a toxic buildup which will lead to experiencing severe side-effects. I would suggest looking at the physical cause of your anxiety. If you have diabetes or alcoholism in your family then it's a good bet that you are a reactive or fasting hypoglycemic. When you blood sugar gets low during the night you may wake up to an adrenaline rush that can be perceived as anxiety or flight. Some people experience it as fight or anger. The following may help. My family has been drug free and anxiety and depression free for almost 2 yrs now since stay off the sugar as best we can. If you are a sugar craver. A glucose test is not necessary. A simple test can be just eating an orange after not eating for awhile a see if 20 min. after eating the orange you feel hunger pangs. If so then you probably a reactive hypoglycemic. Good Luck and God Bless.

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Conquering Anxiety, Depression and Fatigue Without Drugs - the Role of Hypoglycemia

by Professor Joel H. Levitt

The Anxiety & Hypoglycemia Relief Institute

e-mail:***@****

voice-mail:212-479-7805

web-page: http://www.travelersonline.com/anxiety/



(For questions regarding anxiety & hypoglycemia and New York City

classes, contact Prof. Joel H. Levitt ***@****)



Stress is often blamed as the root cause for anxiety, depression and fatigue, but, although stress can make any problem worse, the source of such problems is often physical in nature. And hypoglycemia is one of the major physical causes.



This article covers the following:



What is Hypoglycemia? - the cause of hypoglycemia and its effects.



Typical Hypoglycemia Symptoms - the wide range of mental, emotional and physical symptoms.



Testing for Hypoglycemia - standard medical testing and why it is often unreliable.



The Solution to Hypoglycemia - a list of dietary and nutrient recommendations, with special notes and cautions.



Recommended Reading - books and other references that will give you a more complete understanding.



What is Hypoglycemia?



First of all, let's be clear on one major point - hypoglycemia is not a "disease" in that you either have it or don't, it is a condition, and, in most cases, it is fully reversible.



Some types of hypoglycemia are caused by a tumor or other physical damage to a gland. However, that is rare, and not the focus of this article. The more common type of hypoglycemia - called "functional," "reactive," or "fasting" - is your body's reaction to what you put in it.



Hypoglycemia is the body's inability to properly regulate blood sugar levels, causing the level of sugar in the blood to be too low or to fall too rapidly.



Blood sugar, in the form of glucose, is the basic fuel for all brain operation and physical activity, including muscular. If the available fuel is too inadequate, any marginal physical or mental system may start to shut down. In addition, the glandular imbalances that result, as the glands struggle to regulate the sugar level, cause their own symptoms - especially high adrenaline, which is usually perceived as anxiety or panic, but, in some cases, can lead to violence. (Am I saying this has something to do with domestic violence and street crime? YES! And there is expert congressional testimony to back this up.)



Here is a typical pattern:



1. You eat or drink excess sugar (the average American consumes well over 100 lbs/yr.).



2. The body releases insulin to put sugar into storage, but the insulin response is excessive (due to ADAPTATION and/or chromium deficiency).



3. About 2 hours later so much sugar has been put into storage that there is not enough left in the blood, and you get a low-blood-sugar emergency.



Symptoms such as weakness and mental fog begin.



4. The body responds to the emergency by dumping adrenaline into the system.



More symptoms follow from the high adrenaline, such as racing heart, anxiety, etc., etc., etc..



5. The roller coaster rises and falls in critical hormones, causing an unbalance in all the hormones and often resulting in ongoing symptoms.



Many Americans have hypoglycemia to a greater or less degree. The symptoms comprise a remarkably long list and range from mild discomfort to being completely incapacitated.





Typical Hypoglycemia Symptoms



Following is a list of symptoms I've drawn from multiple sources, plus my own observations. The list is long because symptoms result not only directly from low blood glucose but also from the glandular imbalances that result, especially high adrenaline. Only one or two symptoms may be present, but most often, you will find several.



Note that although I've listed mental and physical symptoms separately, they often overlap.



Mental Symptoms



Anxiety - ranging from constant worry to panic attacks.



Phobias - claustrophobia, agoraphobia, acrophobia, and so on. This is anxiety tied to a particular issue.



Nervousness



Restlessness



Irritability



Depression - especially with females



Violent outbursts - especially with males



Obsessive Compulsive Behavior



Forgetfulness - this may just be choline/inositol deficiency.



Inability to concentrate



Unsocial, Asocial, Anti-Social behavior



Crying spells



Nightmares & night terrors - terror can continue after you wake up. It is especially indicative of hypoglycemia if you wake in a cold sweat, if the terror continues, if there is pressure on the chest, or if you are unable to breathe.



Physical Symptoms



Headaches - especially if a meal is missed.



Tachycardia - racing pulse