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Mental Health  (Expert Forum)
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zyprexa withdrawal
Answered by
Roger Gould, M.D. - Mental Health, Wellness
Questions posted in the Mental Health forum are being answered by Dr. Roger L. Gould, author of the Mastering Stress and Depression program and affiliated with the UCLA. Department of Psychiatry. Topics covered include anger, attention deficit disorder (ADD), bipolar disorder, dementia, electroconvulsive therapy (ECT), learning disabilities, memory, obsessive compulsive disorder (OCD), panic, personality disorders, phobias, post-traumatic stress disorder (PTSD), schizophrenia, stress, transitions, and work problems.

zyprexa withdrawal

by SandraG, Mar 09, 2005 12:00AM
I am currently suffering from zyprexa withdrawal. I have terrible insomnia. Does anyone have any advice? I am interested to hear from others who got off zyprexa successfully, to find out how they did it and how long it took to recover.



thanks!

by Roger Gould, M.D., Mar 14, 2005 12:00AM
I hope others who have had the direct experience will respond, but the general guidelines are it seems to take two to three weeks of gradually coming back to yourself. What you have to be careful of is observing yourself too closely for when you do you tend to interpret the normal fluctuations as symptoms when in fact they are not symptoms, but rapidly changing states of mind that gradually become more integrated and less discrete.
Member Comments (44)

by SandraG, Mar 14, 2005 12:00AM
I went cold turkey off zyprexa twice (I know, not smart)--here is what I have been experiencing:



-a feeling of slight pressure on my brain, as if there is sandpaper there



-my sleep cycle has been disrupted



-emotional blunting--can't feel any emotions except anxiety

by sea123, Mar 22, 2005 12:00AM
I am reaserching information regarding Olanzaphine. My 18 year old friend recently got sectioned and got put on this stuff. I am concerned for her welbeing. I have read some fairly unfavorable side effects. She told me she didnt want to take it but the doctor, or staff thretened her with injections if she didnt take it oraly. Im not sure of her exact condition and am not in the best position to help but whats the best advice anyone can give, I read that this drug is for psycotic episodes, biporic depression, manic, hyper, situations and symptoms. She says she feels lost, away with the faries and really spaced out in general. This isnt the girl I know, and she says shes loosing herself.....Theres plenty of clarity behind the drug, is it helping her?

by SandraG, Apr 09, 2005 12:00AM
Zyprexa is a terrible drug, IMO. I was forced to take it, too. It can cause some scary side effects, most notably, tardive dyskenisia, where your muscles spasm uncontrollably. It can be permanent.

by Mel Ann, Apr 15, 2005 12:00AM
Hello, I'm a 29 year old feamale. Last year my doctor prescribed me Zyprexa for depression and anxiety and I felt great, better than ever before, but after taking this medication for almost six months I had to stop it due to the fact that it made me gain 28 pounds, my doctor stopped it cold turkey. For the last seven months I believe I have suffered from severe withdrawal symtoms to include: Daily nausea, (vommiting everyday), headaches and increased heart rate.  My doctor has discovered that I now have an underactive thyroid and I'm now taking thyroid medication.  My doctor has put me through extensive test to find the cause of my daily nausea/upset stomach. After going through 7 test now and no answers to the cause I'm wondering if I'm suffering from serious Zyprexa withdrawls. After researching Zyprexa side effects and withdrawl systoms I'm not finding any as severe as mine.  If anyone has experienced anything like this before please let me know. I'm in desperate need for some answers.

by SandraG, Apr 23, 2005 12:00AM
hi, your symptoms do sound like zyprexa withdrawal, for sure. I have had similar symptoms

by SandraG, Apr 23, 2005 12:00AM
BTW, doctors are generally clueless about psychotropic drug withdrawals so you might want to educate the doctor so he won't pull people off cold turkey ever again-that's the worst way to go!

by zig zag, May 23, 2005 12:00AM
my son is taking prozac 1 a day with 2.5mg zyprexa daily can these two medications be taken together? he also drinks alcohol.but since he started the zyprexa his chronic nerve pain he has suffered for 7 years has disappeared!

by recovery, May 30, 2005 12:00AM
Three and half yrs ago,I had a psycotic episode. I've been taking zyprexa since then, slowing getting off the medication. The higher the dosage i was on the sicker i felt more depressed couldn't concentrate, bad axienty gained about 40pnds and didn't have my period for almost a year. I felt totally sick with this medication. The highest dosage i was on was 10mg and gosh im glad to say im only taking 1.2mg every second day but i had to do it very slow. Just make sure when reducing this medication that u see a doctor and do it very slow don't cut it cold turkey.

by recovery, May 30, 2005 12:00AM
Three and half yrs ago,I had a psycotic episode. I've been taking zyprexa since then, slowing getting off the medication. The higher the dosage i was on the sicker i felt more depressed couldn't concentrate, bad axienty gained about 40pnds and didn't have my period for almost a year. I felt totally sick with this medication. The highest dosage i was on was 10mg and gosh im glad to say im only taking 1.2mg every second day but i had to do it very slow. Just make sure when reducing this medication that u see a doctor and do it very slow don't cut it cold turkey.

by ihatezyprexa, Jun 12, 2005 12:00AM
i have been on zyprexa since summer 1998.  i had to take it in order to get to sleep as i have to take nardil and it gives me insomnia.  well it works great except i now weigh 265 pounds and i used to weigh 180, omg.  so i need to get off this med before i get diabetic.  well the only problem is i get horrible withdrawal symptoms like my brain is being sucked dry.  any suggestions?

by schizoboy, Jul 07, 2005 12:00AM
is my 2nd day since i ran out zyprexa , i kinda took it prn i had a severe episode , and now i cant afford the reffil im on 20 mg is about 680 bucks so i need to wait for insurance to cover it 3 more days , but mannnn in 2 days no sleep , feeling like after u do cocaine , bad dirty , well like hell , ok i go try to rest sleep i dont think so ,

alex

by zyprexaletsmelive, Jul 10, 2005 12:00AM


    I have been on Zyprexa for five years, since I was almost 16. I gained a lot of weight, but it was very good because I was anorexic before and I finally had to accept a normal female body (taking zyprexa made me SO hungry that I finally realized I can't live without food anymore. I had reached that stage in Anorexia where the literal meaning of the word applied: I didn't feel any hunger anymore. I became kind of inhuman. When I became hungry again, my stomach actually felt like recovering! and I had the mental/emotional ability to do so, and to handle the feeling of "betraying myself" and identifying it as false. In my case it WAS the eating that gained me the pounds, not just ingesting the pill...I think that many people blame the pill without realizing that those times when we feel like eating the cupboards clean (and we do just that) is the reason for the weight gain...but then, it's such a powerful drug, it might actually mess with the thyroid? I don't know). That side-effect, with the combination of what it's supposed to do (lessen psychosis/delusions/anxiety), allowed me to calm down, come back to myself (for the first time!) and function. It DID take a while to get used to (a number of months for full-effect). Now, the very bad thing that I've done all throughout my years on Zyprexa was to decide to not take it anymore, on a whim. My mentality was: "okay, okay, now that I've acquired this wisdom about myself through the drug...I think that's enough, that's all I need to fly in this life...so...goodbye, Zyprexa!" And I was off, cold turkey. I would say I've done that about...6 times. But I always go back, because of the withdrawal+the realization that it has something in it that I NEED to function. Everytime I get off of it, I become a different person who is not someone I want to be. I recently got off for close to 2 months...until I got so sick I felt I was dying, I couldn't even function at work, it was embarrassing, I finally was shivering so bad and feeling hot-flashes+chills and dizziness and everything juuust-fffelllt-weeeiirrrd....I couldn't understand simple things, I was exhausted but I couldn't sleep, my heart was racing, my back hurt, I felt my chest was caving in and I couldn't breathe...and all my anxiety returned and I just went under so fast (felt like I did before I ever went on the med...but worse). Finally, I went into the bathroom and needed to vomit (I don't vomit easily, so it was the pinacle of unwellness for me) and then I decided I couldn't take it anymore so I nibbled off half a Zyprexa (2.5 for me) and within 5 minutes I stopped feeling so cold, and I was able to calm down, and my thoughts made sense again. It was interesting because my brothers and mom saw me shaking and gasping on the couch and not being okay with the slightest noise (I was convinced that everyone was trying to annoy me...I seriously turned into a mega-***** and was very interpersonally paranoid)then I went into my room...and fifteen minutes later I came out and completely normal again. Needless to say, they noticed the difference and were glad to have me back again. I felt shaky...but I'd just put myself through a lot of unnecessary pain for the past two months. I wanted to find out if I still needed it, and if I was well enough on my own natural chemical balance...and I found out that I was not. It's nothing shameful to need a little (perscribed) pill for our well-being. Zyprexa may not be the right med for everyone...but I think that anyone who takes any anti-psychotic medication and knows he/she needs (down in your heart