Questions posted in the Heart Forum have been answered by doctors from The Cleveland Clinic Foundation.

Question Title: Blood Thinners

Forum: The Heart Forum
Topic: Heart Disease

Posted by Lee on June 21, 1999 at 12:41:50

My friend has Marfan's Syndrome. She is 40 years old and has had two heart surgeries to repair aneurysms. She is currently taking Coumadin to thin her blood. Her doctors have told her that she is becoming immune to the Coumadin. She was taking 15 MG of the Coumadin and they have increaced her dosage to 20 MG. They said if this does not work, they will have to hospitalize her and give her Heparin. Are there any other blood thinners that work as well as Coumadin? Does she have any other alternatives than to be hospitalized?


Posted by CCF CARDIO MD JMF on June 21, 1999 at 17:00:10

Dear Lee,

Typically in these cases it is wise to have your friend admitted to the hospital to wean her off coumadin if necessary monitoring her INR (a measure of clotting activity). She can be managed with heparin or low molecular weight heparins if required.

I hope you find this information useful. Information provided in the heart forum is for general purposes only. Only your physician
can provide specific diagnoses and therapies. Please feel free to write back with additional questions.

If you would like to make an appointment at the Cleveland Clinic Heart Center, please call 1-800-CCF-CARE or inquire online
by using the Heart Center website at www.ccf.org/heartcenter. The Heart Center website contains a directory of the cardiology
staff that can be used to select the physician best suited to address your cardiac problem.




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