Questions posted in the Heart Forum have been answered by doctors from The Cleveland Clinic Foundation.

Subject: Re: HDL/LDL also related to thrombosis (and another question)?
Forum: The Heart Forum

Topic Area: Thrombosis

Posted by mariette on August 07, 1999 at 18:05:41

Dear Doctors,

I wrote earlier about thrombosis. I actually have 2 questions.

1.
Today there was something in the papers about a new discovery with respect to cholesterol. They now think that the "good cholesterol" plays a very important role in vesselproblem.

Is it possible that a low cholesterol, and especially low HDL levels could play a role in thrombosis and strokes? If so, what could I do to improve levels?

2.
Given that fact that I have a clotting disorder, suffered 8 DVTs and PEs as well as 3 minor strokes, as well as coronary artery spasms, it is possible that this all leads to an increased risk for an MI?

Thanks, Mariette


Posted by CCF CARDIO MD JMF on August 08, 1999 at 14:41:38

Dear Marriette,

thank you for your questions.

a low HDL or good cholesterol is a potent risk factor for CAD. Two recent studies have suggest that raising HDL will decrease your risk of heart attacks and death. This is best done with niacin, gemfibrozil, exercise or a modest amount of red wine or grape juice.

As far as the link between DVT's and PE's and stroke with MI's. they are related by the risks that cause them, but are not related secondary to thromboisis. PE's and DVT's are in the venous system. HOwever, if you smoke and have other cholesterol abnormalilites, these are risks for CAD.

I hope this has been useful. I wish you the best of luck. Feel free to write back.

Information provided here is for general purposes only. Specific questions should be addressed to your own doctor. If you would like to make an appointment at the Cleveland Clinic Heart Center, please call 1-800-CCF-CARE or inquire online by using the Heart Center website at www.ccf.org/heartcenter. The Heart Center website contains a directory of the cardiology staff that can be used to select the physician best suited to address your cardiac problem.

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