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Questions posted in the
Heart Forum have been answered by doctors from The Cleveland Clinic Foundation.
Question Title: Collateral CirculationForum: The Heart Forum
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I had a heart attack 4 months ago. I have 2 vessel disease with no reversible damage and about 25% of my heart is not working. I am told however that collateral circulation may take place via growth of new veins and improve my heart's performance. I have been unable to find any detail on this phenomenon and so don't know if there is a good chance of this occurring or not. Can you please advise or direct me to sources of information on this subject. I did find a web site for "Enhanced Extended Counterpulsations" which promoted a kind of pressure pads on the legs which forced blood through the heart at increased rates and promoted healing. Is this snake-oil medicine or is it legitimate? ____ Dear Colin, Collateral circulation is something our bodies promote themselves in any tissue that is ischemic (starving for oxygen); ischemia results from decreased circulation to a bed of tissue (leg, heart, etc.) often because there is blockage in the artery supplying oxygen and nutrients to that tissue bed. Now the way that our bodies 'deals' with or promotes 'collateral' flow is not completely understood but it is known that some growth factors are somehow stimulated and literally cause the cells to grow new routes for the blood or new blood vessels. We have known for years that the body can do this because on angiograms of the heart and legs of people with ischemia we can see these as faint lines or very small blood vessels which fill last in the whole picture. We even know that they exist before we see them on angiogram and this has to do with the limitations of our eyes and the equipment. Currently the only patients who receive these growth factors as a treatment are in experimental studies that require the person be quite ill and certainly in a lot of pain. It is probably more important for you to concentrate on keeping that one other artery from getting irreversibly blocked as you say the other two are. Regardless you need comprehensive cardiac care that includes aggressive risk factor management(eliminate smoking, reduce weight and cholesterol, exercise every day, etc.) and medications to help your heart to remodel in the most advantageous way that it can following your heart muscle damage (for instance you should be considered highly for beta blocker and ace-inhibitor therapy.) Honestly we in the medical profession are not at all sure how to enhance the patients' ability to build collateral blood flow however you can read all about what we do know in any medical library by looking up cardiovascular disease or just vascular disease secondary to atherosclerosis. As I said before the growth factor therapy trials are starting but are still in the experimental stages and reserved for those patients for which there is no alternative. The counterpulsation therapy you speak of has not been scientifically tested, nor proven to be of significant benefit to the patient let alone proven that the number of collaterals increases with these treatments;it is in these cases that the patient be reminded that this is really a buyer beware type of situation. On a final note I will say that you should first do the therapies that have been scientifically proven and then consider these off-beat unproven therapies at your own risk (wallet and health included.) Good Luck. Information provided in the Heart Forum is intended for general informational purposes only, actual diagnosis and treatment can only be made by your physician(s).
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