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Heart Disease  (Expert Forum)
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Ferritine effects on valves?
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Ferritine effects on valves?

by Mariette Geest, Oct 22, 1999 12:00AM
Dear Doctors,



Is it true that high Ferritine levels have a negative impact on the heart valves? In what way? And if so indeed, after how many years? What is causing a high level of Ferritine?



Thanks, Mariette

by CCF CARDIO MD - DLB, Oct 22, 1999 12:00AM
Certain genetic disorders such as hemochromatosis can cause markedly elevated levels of ferritin and iron. This can lead to irreversible damage of the heart if left untreated. It would be unlikely to affect the valves without causing a cardiomyopathy as well.
Member Comments (3)

by mariette, Oct 22, 1999 12:00AM
Thanks for the reply. However: it is not quite clear to me.



I am 32 years old now and have significant raised levels of ferritine for years (I would have to check the iron levels).



1.

Is it possible that it affects the heart now (whilst I am in my 30s) or would it have been detected earlier?

2.

How should it be detected?

3.

should a mild valve problem now be checked again later? after a year? longer?





Thanks, Mariette

by CCF CARDIO MD - DLB, Oct 24, 1999 12:00AM
An isolated mild valve problem would just require annual check-ups with your doctor, unless new symptoms develop.



A markedly elevated iron level can damage the heart and lead to heart failure. It would not typically lead to isolated mild valve problems.
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