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Welcome to the Heart Forum! This forum is for questions and support regarding heart issues such as: Angina, Angioplasty, Arrhythmia, Bypass Surgery, Cardiomyopathy, Cornary Artery Disease, Defibrillator, Heart Attack, Heart Disease, High Blood Pressure, Mitral Valve, Pacemaker, PAD, Stenosis, Stress Tests
Questions posted in the Heart Forum are being answered by doctors from The Cleveland Clinic Heart Center.
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| lori 7/6/2001 | . | I am a 28 year old female who has Osteogenesis Imperfecta. I have Aortic Regirg -- Mild to Moderate. I am consisdering starting a drug called PAMIDRONATE in efforts to increase my bond densisty. I was wondering if this drug would impact my heart condition in a negative way.This drug has been around for a while and is used with cancer patients but is showing promise with OI.. Thank you for your assistance. |
| CCF-M.D.-CRC 7/6/2001 | lori | Dear lori, Pamidronate (pa-mi-DROE-nate) is used to treat hypercalcemia (too much calcium in the blood) that may occur with some types of cancer. It is also used to treat Paget's disease of bone and to treat bone metastases (spread of cancer). There are no reported effects on aortic regurg. Here are some potential side-effects. Check with your doctor as soon as possible if any of the following side effects occur: More common Abdominal cramps; chills; confusion; fever; muscle spasms; sore throat; Note: Abdominal cramps, confusion, and muscle spasms are less common when pamidronate is given in doses of 60 mg or less. Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome: More common —at higher doses Nausea; pain and swelling at place of injection. Less common Muscle stiffness. Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor. |
| crash 7/27/2001 C2 | Lori | I hope you check back. I saw your posting and was interested at how much we have in common. I also have OI (mild) and two years ago had AVR due to severe regurgitation. I'd like to share experiences. E-mail me if you would like to. Jskrauss68@aol.com Janelle | [Thread closed to new comments] |
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