Member Comments are provided by individuals and reflect their personal opinions only. Under NO circumstances should you act on any advice or opinion posted in this forum. ALWAYS check with your personal physician before taking any action regarding your health! MedHelp International and our partners, sponsors and affiliates have no obligation to monitor any comments posted on this site, or the content and/or accuracy of such exchanges. MedHelp International does not endorse the views of any user.
Heart Disease (Expert Forum)
Exercise and LAD blockage
Answered by
Cleveland - OH
This forum is for questions and support regarding heart issues such as: Angina, Angioplasty, Arrhythmia, Bypass Surgery, Cardiomyopathy, Coronary Artery Disease, Defibrillator, Heart Attack, Heart Disease, High Blood Pressure, Mitral Valve, Pacemaker, PAD, Stenosis, Stress Tests
Exercise and LAD blockage
by runnertom, Jan 29, 2006 12:00AM
Doctor,
Please forgive me for spouting heresy, but this has been a concern of mine for some time. Three years ago at age 54 I was found to have an LAD blockage that was successfully bypassed. This was almost unbelievable to anyone knowing me as I had been a competitive runner/cyclist/triathalete for 30 years. I had none of the normal cardiac risk factors such as smoking, weight, cholesterol (LDL 130, HDL 60, TG 60), BP, etc. Later testing showed I was high in homocysteine. I come from a family with longevity on both sides.
Over the last three years, I have become aware of several other very heavy exercisers who found themselves in a situation similar to mine-blockage of the LAD at the first bifurcation. It has been speculated that the high amount of turbulence present at that point during heavy exertion could cause an inflamatory response that coupled with other borderline risk factors could cause a gradual lesion formation. Do you think this is completely ridiculous?
The answer to this has great significance to me, as I am back working out as hard as ever, but have this little voice telling me I might be headed right back to the knife. Other than a daily Pravachol tablet that gets my LDL down to 75 and some B vitamins, nothing has really changed in my life that would prevent me from blocking up again. My cardiologist is similarly mystified how anyone doing the exercise I do with an HDL of 60 could have a heart problem.
Please forgive me for spouting heresy, but this has been a concern of mine for some time. Three years ago at age 54 I was found to have an LAD blockage that was successfully bypassed. This was almost unbelievable to anyone knowing me as I had been a competitive runner/cyclist/triathalete for 30 years. I had none of the normal cardiac risk factors such as smoking, weight, cholesterol (LDL 130, HDL 60, TG 60), BP, etc. Later testing showed I was high in homocysteine. I come from a family with longevity on both sides.
Over the last three years, I have become aware of several other very heavy exercisers who found themselves in a situation similar to mine-blockage of the LAD at the first bifurcation. It has been speculated that the high amount of turbulence present at that point during heavy exertion could cause an inflamatory response that coupled with other borderline risk factors could cause a gradual lesion formation. Do you think this is completely ridiculous?
The answer to this has great significance to me, as I am back working out as hard as ever, but have this little voice telling me I might be headed right back to the knife. Other than a daily Pravachol tablet that gets my LDL down to 75 and some B vitamins, nothing has really changed in my life that would prevent me from blocking up again. My cardiologist is similarly mystified how anyone doing the exercise I do with an HDL of 60 could have a heart problem.
Doctor's Answer
by Cleveland Clinic, Jan 29, 2006 12:00AM
, Jan 29, 2006 12:00AM
runner,
One of the most common sites of blockages in the coronary arteries is at sites of bifurcation. This is in all commers including exercisers and non exercisors. You are on the right track in thinking as a lot of people believe shear stress from these sites cause stress leading to accumulation of lipid.
Unfortunately, we only know of a relatively few powerful risk factors that lead to coronary blockages. I see patients often without many of the traditional risk factors and significant coronary atherosclerosis.
Physical actvity and healthy diets have been show to cause coronary plaque to stand still, and in some cases regress. While it would be nice to have something to pin your blockages on, I dont believe it was your physical activity.
Good luck
One of the most common sites of blockages in the coronary arteries is at sites of bifurcation. This is in all commers including exercisers and non exercisors. You are on the right track in thinking as a lot of people believe shear stress from these sites cause stress leading to accumulation of lipid.
Unfortunately, we only know of a relatively few powerful risk factors that lead to coronary blockages. I see patients often without many of the traditional risk factors and significant coronary atherosclerosis.
Physical actvity and healthy diets have been show to cause coronary plaque to stand still, and in some cases regress. While it would be nice to have something to pin your blockages on, I dont believe it was your physical activity.
Good luck
A routine annual test (required because I am a professional pilot) showed a problem last fall. So much for the cardiologist's speculation: my RCA was 80% blocked, requiring a stent. Oddly enough, the LAD blockage was reduced to 30%, and my now-redundant bypass is no longer functional as the body has absorbed the mammary artery. (I joked that the tri victory was a half-hearted effort.)
So: I now feel that CAD is CAD. Once you have it, risk factors are irrelevant: they are predictive, not diagnostic (neither one of us has risk factors, anyway), and there is no point looking for the one bullet that caused the disease. The real issue is how to live with it. We're good patients: we take our meds, eat right, exercise (I was once called a "perfect patient.") But physicians give conflicting advice about how much exercise is "safe": "Not more than an hour." "Don't go anaerobic." "You should be faster." They mostly admit that they are blowing smoke.
It seems that medicine has not addressed the problem of athletes with CAD. As the population ages there will be more and more of us. I would be happy to participate in some kind of longitudinal study that would help uncover reasonable guidelines; I'll bet you would, too. I'd also be interested to read other similar stories; it might help convince the cardiologists that there is a genuine problem to be addressed.
CAD is often a lifestyle disease, and that is the mindset from which our physicians approach our treatment. It is not relevant to us. But risk factors are factors: you multiply the baseline risk by the risk factor to determine individual risk. There is still a baseline risk; that's the source of non-lifestyle CAD.
My personal choice is to keep training but listen to my body. So far, so good.
Good luck.
I guess I keep beating this horse is that my disease seems so perverse in light of my activities and lifestyle. It truly worries me that my continued level of exercise might be killing me, and not by way of an infarct.
I have found in some of my reading that stress or anxiety (more specifically "time anxiety, where you can't tolerate delays or heavy traffic, or need to alway hurry) is a very unappreciated risk factor. I could be a poster boy for this. The lipid specialist convinced me to take a low dose of Paxil for this reason. I do seem to sleep better. It could be that my need to get in my workout every day after work played into this. I am constantly defending my schedule to make sure I get off work in time to run or ride. I guess that can kind of run your life if you let it. I remember former President Clinton saying the first thing he would be thinking when he woke in the morning is when he would get to run. I can identify with the sentiment.
Al, my blockage never resulted in any angina or pain. Transient shortness of breath in the first 1/4 mile of running was my only real symptom. I would never have had a clue from cycling, in spite of pushing myself deep into the "red zone" on virtually every ride. Riding with a group of 50 somethings who feel they could go back and bike race successfully leads to that type of behavior.
My wish at this point is to get some feedback as to how I am doing. I refuse to have another cath to accomplish this, even if the insurance would pay. I'm thinking the new 64 slice gated CT scan would be just the thing. If I thought my disease was progressing to any degree, I guess I would give up meat completely, start taking the Prof's "Draino", and retire.
-- Oscar Wilde
I re-read your reply and have to take issue with one statement:"there is no point in looking for the one bullet that is the cause of the disease". I guess that "looking for the bullet" or bullets has been the focus of my life for the last three years. I feel that if I don't find that or the collection of smaller bullets I am doomed to an early demise. My feeling that the "baseline" risk is nothing other than the average risk of CAD in those who don't have extraordinary risk factors such as smoking, high BP, etc. I don't think the human body has evolved such that CAD at age 50 is a reasonable expectation, even in some small percentage of people. I think the preponderance of evidence suggests that CAD is a result of an accumulation of "pro-CAD" environmental or lifestyle factors that must be minimized to stop the progression of the disease. I just hope I have not overlooked something.
, but kept HR below 160.
Got sick, virus like (fever, lightheaded, nausea for a few weeks) and went back to Cardiologist who lowered my Toprol to 25 mg 1 x per day.
Lightheadedness went away but nausea and heartburn remains. Now after 2 miles I get chest tightness and feel like throwing up and get really acidy. Walking home really bugs me but I don't want to deal with my heart again.
Going to see a GI doc now since my cardiolgist doesn't think it's heart realted since I did a stress test 6 months ago and lasted over 20 minutes.
I need my runs!