Member Comments are provided by individuals and reflect their personal opinions only. Under NO circumstances should you act on any advice or opinion posted in this forum. ALWAYS check with your personal physician before taking any action regarding your health! MedHelp International and our partners, sponsors and affiliates have no obligation to monitor any comments posted on this site, or the content and/or accuracy of such exchanges. MedHelp International does not endorse the views of any user.
Heart Disease (Expert Forum)
Mitral Valve and Lisinopril
Answered by
Cleveland - OH
This forum is for questions and support regarding heart issues such as: Angina, Angioplasty, Arrhythmia, Bypass Surgery, Cardiomyopathy, Coronary Artery Disease, Defibrillator, Heart Attack, Heart Disease, High Blood Pressure, Mitral Valve, Pacemaker, PAD, Stenosis, Stress Tests
Mitral Valve and Lisinopril
by PRRK4s, Oct 27, 2006 12:00AM
Hello, thank you for taking the time to answer this question. I have been diagnosed with Mitral Valve Leakage. I do not know the specific RF numbers associated with this. I read via the net that in time either mitral valve repair or replacement may be needed. The Cardiologist I am seeing has placed me on 5mg of Lisinoril. I am wondering if this is a theorpy for deplaying surgery or is it a long term plan to treat the leakage. I am also on 25mg Metoprolol twice daily. I will be having a heart cath in 2 weeks to investigate the valve further and to rule out any other damage. Please advise of the results of other Lisinopril treatment history. Thanks....G
Doctor's Answer
by Cleveland Clinic, Oct 27, 2006 12:00AM
, Oct 27, 2006 12:00AM
PRRK4s,
Thanks for the post.
There isnt a lot of data to show effects of ACE inhibitors on mitral regurgitation. The idea behind using ACE inhibitors in this condition lies in reducing the resistance to forward flow out of the left ventricle thereby decreasing the amount of backward flow through the mitral valve into the left atrium. There is some data showing improvement in remodeling and reduction of left atrial size using this therapy. Overall, if you have hypertension then it is reasonable to use this therapy -- but mainly for the hypertension. However, without hypertension and in the setting of a normal ejection fraction and no symptoms then there would be no reason for the therapy. If you have severe regurgitation and and symptoms or decreased LV fucntion then surgical therpay would be indicated.
good luck
Thanks for the post.
There isnt a lot of data to show effects of ACE inhibitors on mitral regurgitation. The idea behind using ACE inhibitors in this condition lies in reducing the resistance to forward flow out of the left ventricle thereby decreasing the amount of backward flow through the mitral valve into the left atrium. There is some data showing improvement in remodeling and reduction of left atrial size using this therapy. Overall, if you have hypertension then it is reasonable to use this therapy -- but mainly for the hypertension. However, without hypertension and in the setting of a normal ejection fraction and no symptoms then there would be no reason for the therapy. If you have severe regurgitation and and symptoms or decreased LV fucntion then surgical therpay would be indicated.
good luck
Expert Activity
Related Expert Forums
Related Communities