Question Title: Barrett's Esophagus and Accutane

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Dear Arty:

Accutane (isotretinoin) remains the most effective anti-acne therapy available. Since it was approved for the treatment of severe acne in the early 1980s, more that 7 million patients have received this medication..
The most common side effects of Accutane are dryness of the mouth, nose and eyes. It also commonly produces some redness of the facial skin with increased sensitivity to ultraviolet light. About 15% of the patients taking Accutane complain of some muscle or joint pain, usually relieved with over-the-counter analgesics like Tylenol.
Because in some rare cases patients taking Accutane developed abnormal liver blood tests and high cholesterol, most physicians routinely check these blood tests before starting treatment.
Accutane has also been safely used in many chronic diseases such as inflammatory bowel disease (ulcerative colitis and Crohn's disease), epilepsy, diabetes, multiple sclerosis, renal insufficiency and heart or kidney transplant patients.
Using a computerized medical literature database we could not find any references to Accutane treatment in Barrett's Disease or interactions between Accutane and Prilosec. One source of information on adverse events occurring during treatment with Accutane is the Roche Safety Database. They did not have any reported interactions between Prilosec and Accutane or in patients with Barrett's esophagus.
Despite the lack of specific information about the use of Accutane in patients with Barrett's esophagus taking Prilosec, it is probably safe to remain under the supervision of your Dermatologist.
This information is provided for educational purposes only. Always consult your physician for specific medical questions.
HFHSM.D.-ab
*keywords: Barrett's esophagus, Prilosec, adolescent, Accutane
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